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Early schizophrenia symptoms include unusually high CA1 subfield activity

In the first functional magnetic resonance imaging (fMRI) study of its kind, neurologists and psychiatrists at Columbia University have identified an area of the brain involved in the earliest stages of schizophrenia and related psychotic disorders.

7 Sep 2009

Iterative in situ click chemistry creates antibody-like protein-capture agents

Chemists at the California Institute of Technology (Caltech) and The Scripps Research Institute (SRI) have developed an innovative technique to create cheap but highly stable chemicals that have the potential to take the place of the antibodies used in many standard medical diagnostic tests. James R. Heath, Ph.D., principal investigator of the Nanosystems Biology Cancer Center at Caltech, one of eight Centers of Cancer Nanotechnology Excellence, and K. Barry Sharpless, Ph.D., SRI, and their colleagues describe the new technique in the journal Angewandte Chemie International Edition.

7 Sep 2009

Specific targeting of brain tumors with an optical/magnetic resonance imaging nanoprobe across the blood-brain barrier

Earlier this year, researchers at the University of Washington reported that they had developed a toxin-nanoparticle combination that inhibits brain cancer invasion when added to tumor cells growing in culture.

7 Sep 2009

Molecularly targeted nanocarriers deliver the cytolytic peptide melittin specifically to tumor cells in mice, reducing tumor growth

When bees sting, they pump into their victims a peptide toxin called melittin that destroys cell membranes. Now, by encapsulating this extremely potent molecule within a nanoparticle, researchers at the Washington University School of Medicine in St. Louis have created a potential new type of anticancer therapy with the potential to target a wide range of tumors. This work was reported in the Journal of Clinical Investigation.

7 Sep 2009

Regurin XL capsule for the treatment of OAB launched in UK

Regurin(R) XL (trospium chloride), a once-daily, prolonged-release capsule to treat patients with overactive bladder (OAB) has been launched in the UK. Regurin(R) XL provides rapid, significant and consistent improvements in the symptoms of OAB1 and has a reduced potential for central nervous system (CNS) side effects(2-7).

7 Sep 2009

IRS1 gene could lead to better treatment of type 2 diabetes

A breakthrough by an international team of researchers in Canada, France, the UK and Denmark has uncovered a new gene that could lead to better treatment of type 2 diabetes, as well as a better understanding of how this widespread disease develops.

7 Sep 2009

Two more genetic risk factors for Alzheimer's disease discovered

An international team of scientists has identified two more genetic risk factors for Alzheimer's disease. The findings are reported in the online edition of the journal Nature Genetics.

7 Sep 2009

Better health system needed to identify and manage childhood obesity

A new study has revealed GPs and pediatricians believe their capacity to effectively identify and manage childhood obesity is limited, due to barriers such as time constraints. 65 per cent of the doctors also perceived a shortfall in public sector dietitians to assist them in managing overweight and obese children, according to the study in Nutrition & Dietetics, published by Wiley-Blackwell.

7 Sep 2009

Harmless shard from childhood virus shell may halt biological process

A harmless shard from the shell of a common childhood virus may halt a biological process that kills a significant percentage of battlefield casualties, heart attack victims and oxygen-deprived newborns, according to research presented Sunday, September 6, 2009, at the 12th European meeting on complement in human disease in Budapest, Hungary.

7 Sep 2009

Scientists identify new genetic variations that are associated with type 2 diabetes

Scientists have identified a genetic variation in people with type 2 diabetes that affects how the body's muscle cells respond to the hormone insulin, in a new study published today in Nature Genetics.

7 Sep 2009

Angiotensin II receptors not detectable in pregnant or preeclamptic women

A new study by researchers at Wake Forest University School of Medicine reveals a key component in the development of preeclampsia in pregnant women, a condition that can result in miscarriage and maternal death.

5 Sep 2009

Olympic gold medalist Shannon Miller to campaign for Stemcyte

StemCyte, Inc., one of the world's preeminent cord blood banks, today announced that Shannon Miller, a 7-time Olympic Medalist and 9-time World Medalist, has signed an endorsement partnership agreement and will appear in a series of advertising and public awareness campaigns for the company.

5 Sep 2009

Flu vaccinations now available at all 22 Target Clinic locations

Target(R) announces that flu vaccinations are now available at all 22 Target Clinic locations in Minnesota. The Centers for Disease Control and Prevention recommends nearly everyone protect themselves against this potentially serious illness.

5 Sep 2009

Aflac Ford Fusion to sport 13-year-old cancer patient's paint scheme

On September 6(th), at Atlanta Motor Speedway, the No. 99 Aflac Ford Fusion will sport a colorful new look inspired by a 13-year-old patient at the Aflac Cancer Center. Aflac invited children at the Aflac Cancer Center and Blood Disorders Service to "Color Carl's Car" for the Labor Day weekend race.

5 Sep 2009

microRNAs analysis could detect pancreatic cancer

A blood test for small molecules abnormally expressed in pancreatic cancer may be a promising route to early detection of the disease, researchers at The University of Texas M. D. Anderson Cancer Center report in the September edition of the journal Cancer Prevention Research.

5 Sep 2009

New approach for understanding how drug resistance occurs in leukemia

UCSF researchers have developed a new approach to identify specific genes that influence how cancer cells respond to drugs and how they become resistant. This strategy, which involves producing diverse genetic mutations that result in leukemia and associating specific mutations with treatment outcomes, will enable researchers to better understand how drug resistance occurs in leukemia and other cancers, and has important long-term implications for the development of more effective therapies.

5 Sep 2009

New role discovered for sphingosine-1-phosphate

Virginia Commonwealth University School of Medicine researchers have discovered a new role for the bioactive lipid messenger, sphingosine-1-phosphate, or S1P, that is abundant in our blood - a finding that could lead to a new generation of drugs to fight cancer and inflammatory disease.

5 Sep 2009

Insomnia increases blood pressure

Can't sleep at night? A new study published in the journal Sleep has found that people who suffer from insomnia have heightened nighttime blood pressure, which can lead to cardiac problems. The investigation, which measured the 24-hour blood pressure of insomniacs compared to sound sleepers, was conducted by researchers from the Universit- de Montr-al, its affiliated H-pital du Sacr--C-ur de Montr-al Sleep Disorders Centre and the Universit- Laval.

5 Sep 2009

Alcohol is harmful for unborn babies

Learning disabilities, mental health issues and behavior problems are just some of the issues that afflict babies exposed to alcohol in the womb, yet some doctors still tell their patients it is safe to have a drink now and then while pregnant.

5 Sep 2009

Discovery of two antibodies could move AIDS vaccine development forward

Scientists from Scripps Research Institute on Thursday announced they have discovered and isolated two antibodies "with the ability to neutralize [or block the action of] many strains of the AIDS virus, a discovery that might help create a long-sought vaccine against the deadly disease," Bloomberg reports.

5 Sep 2009