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Genetic testing technology wrongly detects the presence of very rare genetic variants

A technology that is widely used by commercial genetic testing companies is "extremely unreliable" in detecting very rare variants, meaning results suggesting individuals carry rare disease-causing genetic variants are usually wrong, according to new research published in the BMJ.

15 Feb 2021

Study: Cytoglobin drug could delay the progression of liver fibrosis in mice

Researchers have discovered that the use of Cytoglobin (CYGB) as an intravenous drug could delay liver fibrosis progression in mice.

15 Feb 2021

What makes some people COVID superspreaders?

The study, published in the journal Proceedings of the National Academy of Sciences, showed that older, obese people who have an acute COVID-19 infection release more aerosols, increasing viral transmission potential.

15 Feb 2021

Nanoparticle COVID-19 vaccine stimulates robust and long lasting immunity in primates

In the study, published on the preprint server bioRxiv, the team evaluated the ability of AS03, CpG 1018 formulated in Alum, the TLR-7 agonist adsorbed to Alum (AS37), the squalene-in-water emulsion (O/W), and Alum to boost protective immunity against SARS-CoV-2.

15 Feb 2021

Drinking, smoking, and drug use may increase risk of premature heart disease in young people

Recreational drinking, smoking, and drug use is linked to premature heart disease in young people, particularly younger women, finds research published online in the journal Heart.

15 Feb 2021

One-size-fits-all approach to evaluating blood pressure could be detrimental to women’s health

A new study from the Smidt Heart Institute at Cedars-Sinai shows that women have a lower "normal" blood pressure range compared to men. The findings were published today in the peer-reviewed journal Circulation.

15 Feb 2021

Research shows rapid global spread of Southern California COVID-19 strain

A new strain of the coronavirus in Southern California, first reported last month by Cedars-Sinai, is rapidly spreading across the country and around the world as travelers apparently carry the virus with them to a growing list of global destinations, according to new research published today in the peer-reviewed Journal of the American Medical Association.

15 Feb 2021

Study: Targeted therapy prolongs survival in patients with advanced bladder cancer

In a new study led by researchers at Yale Cancer Center, the drug enfortumab vedotin (EV) significantly prolonged survival as compared with standard chemotherapy in patients with locally advanced or metastatic urothelial carcinoma or bladder cancer, who had previously received platinum-based treatment and a PD-1–PD-L1 inhibitor.

15 Feb 2021

UTEP professor's discovery could lead to a way to inhibit overeating

Science is a step closer to a new response to obesity, thanks in part to a study conducted by a team that included Sergio Iñiguez, Ph.D., associate professor of psychology at The University of Texas at El Paso.

15 Feb 2021

Scientists study how a single gene alteration may have separated modern humans from extinct hominins

As a professor of pediatrics and cellular and molecular medicine at University of California San Diego School of Medicine, Alysson R. Muotri, PhD, has long studied how the brain develops and what goes wrong in neurological disorders.

15 Feb 2021

Study broadens the definition of self-injury mortality to encompass most drug overdose deaths

Classifying a death as suicide may be easiest for medical examiners and coroners in the western United States, which reports the highest suicide rates officially. Suicide by firearm is the leading method there, and usually clear in terms of evidence.

15 Feb 2021

Study suggests a new way to personalize anti-CTLA-4 therapy for cancers

A Ludwig Cancer Research study has identified a novel mechanism by which a type of cancer immunotherapy known as CTLA-4 blockade can disable suppressive immune cells to aid the destruction of certain tumors.

15 Feb 2021

Research shows how chemicals in the tumor microenvironment enable cancer to evade attack

A paper published today in Nature shows how chemicals in the areas surrounding tumors--known as the tumor microenvironment--subvert the immune system and enable cancer to evade attack. These findings suggest that an existing drug could boost cancer immunotherapy.

15 Feb 2021

Controlling cardiovascular disease risk factors early in life may protect against later dementia

Employing cardiovascular disease prevention strategies in mid-life may delay or stop the brain alterations that can lead to dementia later in life, according to a study in the Journal of the American College of Cardiology.

15 Feb 2021

Cancer research efforts hampered by lack of stable funding and insufficient protected time

Translating laboratory discoveries to clinical care for patients with cancer is a difficult process. Much of the effort is carried by researchers who are also trained as physicians, especially a subgroup known as clinician investigators.

15 Feb 2021

$Research uncovers mechanism responsible for formation of toxic fracking byproducts$

Research uncovers mechanism responsible for formation of toxic fracking byproducts

Hydraulic fracturing, also known as "fracking," relies on water, sand and other chemicals to clear the way for engineers to remove oil or gas from shale - porous rocks below the ground.

15 Feb 2021

First wearable device for simultaneous monitoring of cardiovascular signals and biochemical levels

Engineers at the University of California San Diego have developed a soft, stretchy skin patch that can be worn on the neck to continuously track blood pressure and heart rate while measuring the wearer's levels of glucose as well as lactate, alcohol or caffeine.

15 Feb 2021

Pitt scientists develop fast, efficient technique for discovering tiny antibody fragments

By capitalizing on a convergence of chemical, biological and artificial intelligence advances, University of Pittsburgh School of Medicine scientists have developed an unusually fast and efficient method for discovering tiny antibody fragments with big potential for development into therapeutics against deadly diseases.

15 Feb 2021

Study finds link between brain metabolism, cardiovascular risk, and atherosclerosis

The links between cardiovascular disease and cognitive impairment begin years before the appearance of the first clinical symptoms of either condition.

15 Feb 2021

New type of surgery can help amputees better control their residual muscles

MIT researchers have invented a new type of amputation surgery that can help amputees to better control their residual muscles and sense where their "phantom limb" is in space.

15 Feb 2021

Research News and Research

Genetic testing technology wrongly detects the presence of very rare genetic variants

Study: Cytoglobin drug could delay the progression of liver fibrosis in mice

What makes some people COVID superspreaders?

Nanoparticle COVID-19 vaccine stimulates robust and long lasting immunity in primates

Drinking, smoking, and drug use may increase risk of premature heart disease in young people

One-size-fits-all approach to evaluating blood pressure could be detrimental to women’s health

Research shows rapid global spread of Southern California COVID-19 strain

Study: Targeted therapy prolongs survival in patients with advanced bladder cancer

UTEP professor's discovery could lead to a way to inhibit overeating

Scientists study how a single gene alteration may have separated modern humans from extinct hominins

Study broadens the definition of self-injury mortality to encompass most drug overdose deaths

Study suggests a new way to personalize anti-CTLA-4 therapy for cancers

Research shows how chemicals in the tumor microenvironment enable cancer to evade attack

Controlling cardiovascular disease risk factors early in life may protect against later dementia

Cancer research efforts hampered by lack of stable funding and insufficient protected time

Research uncovers mechanism responsible for formation of toxic fracking byproducts

First wearable device for simultaneous monitoring of cardiovascular signals and biochemical levels

Pitt scientists develop fast, efficient technique for discovering tiny antibody fragments

Study finds link between brain metabolism, cardiovascular risk, and atherosclerosis

New type of surgery can help amputees better control their residual muscles

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