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Compound called apolipoprotein B in blood better at predicting coronary heart disease in Chinese people

Scientists report in the November 2007 issue of the Journal of Lipid Research that the concentration of a compound called apolipoprotein B in the blood is better at predicting whether Chinese have coronary heart disease – in which fatty deposits clog arteries that supply blood and oxygen to the heart – than other substances such as blood cholesterol levels.

12 Oct 2007

Anticlotting drug found to be safe in sickle cell patients

An intravenous "blood thinner" widely used in patients with acute coronary syndromes and during coronary artery stent placement appears to be safe in patients with sickle cell disease and may have beneficial anti-inflammatory effects, a small study at the University of North Carolina at Chapel Hill School of Medicine has found.

12 Oct 2007

Mario Capecchi shares Nobel Prize in medicine for knockout mice technology

Mario R. Capecchi, Ph.D., distinguished professor of human genetics and biology at the University of Utah's Eccles Institute of Human Genetics and a Howard Hughes Medical Institute investigator, has won the 2007 Nobel Prize in Physiology or Medicine.

9 Oct 2007

Sir Martin Evans wins Nobel prize for stem cell research

Medical Research Council funded scientist Sir Martin Evans, has been awarded the Nobel Prize in Physiology or Medicine for 2007 alongside Mario R. Capecchi and Oliver Smithies for their discoveries of "principles for introducing specific gene modifications in mice by the use of embryonic stem cells".

9 Oct 2007

Completion of first clinical trial of Apatone for cancer treatment

In a significant advancement in the ongoing battle against cancer, a group of researchers from Summa Health System, IC-MedTech and other institutions have completed the first ever FDA-approved human clinical trial of Apatone®.

8 Oct 2007

Researchers report most complete list so far of the proteins present in the cerebral cortex

Researchers report in the October 2007 issue of Molecular & Cellular Proteomics the most complete list so far of the proteins present in the cerebral cortex – the outermost layer of the brain that plays a central role in memory, language, cognition, and consciousness.

8 Oct 2007

Proteins found that could be used to improve diagnosis of hepatocellular carcinoma

Researchers report in the October 2007 issue of Molecular & Cellular Proteomics that they have identified proteins that could be used to improve the diagnosis of hepatocellular carcinoma, the most common type of liver cancer.

8 Oct 2007

Improving diagnosis of cancer by detecting protein-sugar structures

Researchers report in the October 2007 issue of Molecular & Cellular Proteomics that they have developed a new way of detecting the abnormal presence of complexes of sugars and proteins in the blood of cancer patients, thus providing a new tool for cancer diagnosis.

8 Oct 2007

Discovery offers hope of halting motor neurone disease progression

Scientists have discovered a causal link between the gene for a small protein involved in the formation of blood vessels and the development of some forms of motor neurone disease.

4 Oct 2007

Missouri-Columbia researchers look at mechanisms of cisplatin drug sensitivity

Resistance to chemotherapy treatments can be the worst news a cancer patient ever receives. A pair of researchers at the University of Missouri-Columbia is working steadfastly to learn why some tumors eventually build a tolerance to the common chemotherapy drug cisplatin, in hopes of identifying the particular genes that can be manipulated to make treatment as effective as possible.

3 Oct 2007

Worm study sheds light on how the human body ages

Microscopic worms used for scientific research are living longer despite cellular defects, a discovery that is shedding light on how the human body ages and how doctors could one day limit or reverse genetic mutations that cause inherited diseases, according to a new University of Colorado at Boulder study.

2 Oct 2007

Potential new therapy for uveitis

An inflammatory eye condition that is one of the world's leading causes of blindness could be treated much more effectively and easily thanks to a new discovery here.

29 Sep 2007

New view of what causes greatest genetic variability among individuals

A study by Yale researchers offers a new view of what causes the greatest genetic variability among individuals - suggesting that it is due less to single point mutations than to the presence of structural changes that cause extended segments of the human genome to be missing, rearranged, or present in extra copies.

27 Sep 2007

Variation in drug responses can be analyzed by studying simpler organisms like plants

While prescription medications work successfully to cure an ailment in some people, in others the same dose of the same drug can cause an adverse reaction or no response at all.

27 Sep 2007

Scientists capture first optical images of carbon nanotubes inside a living organism

Using fruit flies, the researchers confirmed that a technique developed at Rice -- near-infrared fluorescent imaging -- was capable of detecting DNA-sized nanotubes inside living fruit flies.

25 Sep 2007

Breakthrough in cardiovascular research

Cholesterol contributes to atherosclerosis - a condition that greatly increases the risk of heart attack and stroke - by suppressing the activity of a key protein that protects the heart and blood vessels, researchers at the Saint Louis University School of Medicine have found.

18 Sep 2007