Biomarker News and Research

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A biomarker is a biological molecule found in blood, other body fluids, or tissues that is a sign of a normal or abnormal process, or of a condition or disease. A biomarker may be used to see how well the body responds to a treatment for a disease or condition. Also called molecular marker and signature molecule.

Scientists identify two brain networks in Parkinson's

The disease that causes tremors, rigidity and slowed movements in a million Americans also targets another brain network that regulates cognitive thought and the ability to carry out everyday tasks.

10 Jul 2007

Researchers discover how microRNAs control protein synthesis

While most RNAs work to create, package, and transfer proteins as determined by the cell's immediate needs, miniature pieces of RNA, called microRNAs (miRNAs) regulate gene expression.

10 Jul 2007

Debate on folic acid fortification

Since the institution of nationwide folic acid fortification of enriched grains in the mid 1990s, the number of infants born in the United States and Canada with neural tube defects has declined by 20 percent to 50 percent.

10 Jul 2007

Postmenopausal Asian women who eat a Western diet at greater risk of developing breast cancer

Postmenopausal Asian women who eat a "meat-sweet" or Western diet are at greater risk of developing breast cancer than those who eat a "vegetable-soy" diet, according to a new study. The findings mark the first time an association between a Western diet and breast cancer has been identified in Asian women.

10 Jul 2007

Simple bladder cancer test

University of Florida researchers have identified a set of proteins that appear to signal the presence of bladder cancer, a discovery they hope will lead to a simple, fast and noninvasive test that can detect the disease early.

9 Jul 2007

New criteria for probable Alzheimer's disease

An international group of Alzheimer's disease (AD) experts have proposed new criteria for the reasearch diagnosis of the condition, as they argue the existing criteria are out of date due to unprecedented growth of scientific knowledge in the field. The proposal is put forward in a Position Paper published early Online and in the August edition of The Lancet Neurology.

9 Jul 2007

Exercise reduces inflammation

Although a number of studies have suggested that regular exercise reduces inflammation a condition that is predictive of cardiovascular and other diseases, such as diabetes it is still not clear whether there is a definitive link.

9 Jul 2007

Myeloperoxidase offers clues to heart attack in seemingly healthy people

We've all wondered how a seemingly healthy person can actually be at high risk for heart disease or a heart attack.

4 Jul 2007

Targeted nalmefene with simple medical management in the treatment of heavy drinkers

Problem drinkers who took a craving-curbing drug whenever they felt the desire to imbibe reported fewer heavy drinking days each month than drinkers who took a look-alike placebo pill, but both groups reported marked reductions in heavy drinking days.

4 Jul 2007

Dark chocolate lowers blood pressure

Eating about 30 calories a day of dark chocolate was associated with a lowering of blood pressure, without weight gain or other adverse effects, according to a study in the July 4 issue of JAMA: The Journal of the American Medical Association.

4 Jul 2007

Myeloperoxidase protein provides clues to heart attacks in healthy people

We've all wondered how a seemingly healthy person can actually be at high risk for heart disease or a heart attack.

4 Jul 2007

Absence of a gene called CD38 is a protective barrier to obesity

A search for the molecular clues of longevity has taken Mayo Clinic researchers down another path that could explain why some people who consume excessive calories don't gain weight.

27 Jun 2007

Scientists discover proteins in blood that accurately identify colon cancer and precancerous polyps

Initial studies of the proteins, CCSA-3 and CCSA-4, suggest they could be used to develop a blood test to identify at-risk individuals.

19 Jun 2007

Unexplained late-life weight loss may be early predictor of Alzheimer's disease

New findings show unexplained weight loss that precedes dementia by more than 10 years is associated with the severity of Alzheimer changes in the brain.

16 Jun 2007

U-M Health and Retirement Study scientists practice what their research shows most Americans want

When Bob Willis thought about retiring, he knew just how he wanted to do it. Slowly. Or maybe never.

16 Jun 2007

Early life sun exposure linked to melanomas with BRAF gene mutations

Skin cancers often contain different gene mutations, but just how these mutations contribute to the cause of melanomas has been a mystery.

16 Jun 2007

Early results from Alzheimer's neuroimaging studies could speed research

Disease researchers may be able to reduce the time and expense associated with clinical trials, according to early results from the Alzheimer's Disease Neuroimaging Initiative (ADNI), a public-private research partnership organized by the National Institutes of Health.

14 Jun 2007

What makes people susceptible to rheumatoid arthritis?

Peter K. Gregersen, MD, stares at x-rays of hands, searching out the telltale signs of inflamed joints and wrists from his research subjects with rheumatoid arthritis. With these clinical features at his side, he turns to the basic building blocks of life , the human genome , to figure out what makes these people susceptible to the disabling inflammatory condition.

14 Jun 2007

Novel pathways and markers for diagnosis and treatment of bipolar disorder

Looking into the brain is yielding vital clues to understanding, diagnosing and treating bipolar disorder, according to findings being presented at the Seventh International Conference on Bipolar Disorder.

8 Jun 2007

breakthrough in the treatment of idiopathic pulmonary haemosiderosis

Researchers at Queen Mary University London and the University of Leicester and have announced a potential breakthrough in the treatment of a rare but devastating medical condition that can affect children and young people.

5 Jun 2007