Genes News and Research

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New underlying cause of Wiskott-Aldrich syndrome discovered

Researchers at the Salk Institute and King Abdullah University of Science and Technology (KAUST) in Saudi Arabia have discovered a new underlying cause of Wiskott-Aldrich syndrome, a rare genetic disease that leads to bleeding and immune deficiencies in babies.

13 Jul 2022

Mount Sinai receives $4.2 million to establish a Proteogenomic Data Analysis Center

The Office of Cancer Clinical Proteomics Research at the National Cancer Institute has awarded $4.2 million over five years to Mount Sinai researchers establishing a Proteogenomic Data Analysis Center to advance cancer research and treatments.

13 Jul 2022

Study identifies a protein that plays key role in protecting the gastrointestinal tract from inflammation

A protein called Zbtb46, expressed by specialized immune cells, has a major role in protecting the gastrointestinal tract from excessive inflammation, according to a study from researchers at Weill Cornell Medicine.

13 Jul 2022

Study reveals tiny gene fragments as crucial new players in retinal development and vision

Researchers at the Centre for Genomic Regulation in Barcelona reveal that Srrm3 is a master regulator gene crucial for the development of photoreceptors, cells in the back of the retina which capture and process light, sending signals to the brain that enable vision.

13 Jul 2022

What are the biological features, prevention and control strategies against monkeypox?

Researchers elucidated the epidemiology and clinical presentation, biological features, pathogenicity and prevention and control strategies for monkeypox virus (MPXV) infections.

13 Jul 2022

Study suggests ZCB11 as a promising antibody drug against all SARS-CoV-2 variants of concern

Researchers at the AIDS Institute, The University of Hong Kong, Department of Microbiology, School of Clinical Medicine, the LKS Faculty of Medicine of The University of Hong Kong and the State Key Laboratory of Emerging Infectious Diseases, HKU, together with structural biologists at The Hong Kong University of Science and Technology, have demonstrated that ZCB11, a broadly neutralizing antibody derived from a local mRNA-vaccinee against the spreading Omicron variants of SARS-CoV-2, displays potent antiviral activities against all variants of concern (VOCs), including the dominantly spreading Omicron BA.1, BA1.1 and BA.2.

13 Jul 2022

Constant activation of p53 in hepatocytes of CLD patients could promote the development of liver cancer

p53 is one of the most important proteins in cancer biology. Often referred to as a "guardian of the genome," p53 becomes activated in response to various cellular stressors like DNA damage.

12 Jul 2022

Study calls for more conservation efforts to preserve adaptive DNA diversity of dolphin populations

The first widespread census of the genetic diversity of common dolphin (Delphinus delphis) populations living along 3000km of Australia's southern coastline has raised key pointers for future conservation efforts.

12 Jul 2022

Network-based machine learning method helps predict cancer patients' response to immunotherapy

Immunotherapy is a new cancer treatment that activates the body's immune system to fight against cancer cells without using chemotherapy or radiotherapy.

12 Jul 2022

How may the genetic differences observed in the current monkeypox virus outbreak impact immune responses induced by VACV vaccines?

Researchers assessed the impact of the vaccinia virus vaccine on the immune response against the monkeypox virus.

12 Jul 2022

What is the long-term protection against COVID-19?

A new study describes the immunologic parameters associated with protection from COVID-19.

12 Jul 2022

Researchers create a comprehensive map of how complex networks of genes function together

Using new technologies to study thousands of genes simultaneously within immune cells, researchers at Gladstone Institutes, UC San Francisco (UCSF), and Stanford School of Medicine have created the most detailed map yet of how complex networks of genes function together.

11 Jul 2022

Researchers receive $3.25 million NIH grant to better understand the oral manifestations of HIV

Researchers at the Case Western Reserve University School of Dental Medicine will use a $3.25 million grant from the National Institutes of Health (NIH) to better understand how HIV impacts the human body, from mouth lesions to oral cancer.

11 Jul 2022

Newly-discovered historical information reveals that Mendel was decades ahead of his time

Gregor Mendel, the Moravian monk, was indeed "decades ahead of his time and truly deserves the title of 'founder of genetics.'" So concludes an international team of scientists as the 200th birthday of Mendel approaches on 20 July.

11 Jul 2022

Activation of the STING pathway could help make glioblastoma multiforme more susceptible to immunotherapy

Immunotherapy has revolutionized treatment for many forms of cancer, but glioblastoma multiforme (GBM), the most common and deadly form of brain cancer, has remained untouched.

11 Jul 2022

Novel molecular pathway may explain how stress affects neuropsychiatric lupus

A novel molecular pathway involving cell signaling proteins in the brain may explain how stress affects neuropsychiatric lupus with diffuse neuropsychological manifestations.

11 Jul 2022

Researchers identify substantial lack of racial and ethnic data in studies of rare genetic disorder

In a review of published research papers, investigators from the Johns Hopkins Medicine Hereditary Hemorrhagic Telangiectasia Center have identified a substantial lack of racial and ethnic data that may be negatively impacting the treatment and diagnosis of this rare disorder in diverse patients.

11 Jul 2022

Study sheds light on cell type-specific biomarkers of melanoma

A new UC Davis-led study sheds light on cell type-specific biomarkers, or signs, of melanoma. The research was recently published in the Journal of Investigative Dermatology.

10 Jul 2022

Salk professor wins $2 million to gain better understanding of cassava genetics

Research Professor Todd Michael will receive nearly $2 million from the Bill & Melinda Gates Foundation to sequence the genomes of multiple lineages of the cassava plant, a large starchy root vegetable also known as yuca root consumed in more than 80 countries around the world.

8 Jul 2022

Study illustrates how the use of whole exome sequencing can better predict treatment response

Immunotherapies, such as immune checkpoint inhibitors, have transformed the treatment of advanced stage cancers.

8 Jul 2022

Genes News and Research

New underlying cause of Wiskott-Aldrich syndrome discovered

Mount Sinai receives $4.2 million to establish a Proteogenomic Data Analysis Center

Study identifies a protein that plays key role in protecting the gastrointestinal tract from inflammation

Study reveals tiny gene fragments as crucial new players in retinal development and vision

What are the biological features, prevention and control strategies against monkeypox?

Study suggests ZCB11 as a promising antibody drug against all SARS-CoV-2 variants of concern

Constant activation of p53 in hepatocytes of CLD patients could promote the development of liver cancer

Study calls for more conservation efforts to preserve adaptive DNA diversity of dolphin populations

Network-based machine learning method helps predict cancer patients' response to immunotherapy

How may the genetic differences observed in the current monkeypox virus outbreak impact immune responses induced by VACV vaccines?

What is the long-term protection against COVID-19?

Researchers create a comprehensive map of how complex networks of genes function together

Researchers receive $3.25 million NIH grant to better understand the oral manifestations of HIV

Newly-discovered historical information reveals that Mendel was decades ahead of his time

Activation of the STING pathway could help make glioblastoma multiforme more susceptible to immunotherapy

Novel molecular pathway may explain how stress affects neuropsychiatric lupus

Researchers identify substantial lack of racial and ethnic data in studies of rare genetic disorder

Study sheds light on cell type-specific biomarkers of melanoma

Salk professor wins $2 million to gain better understanding of cassava genetics

Study illustrates how the use of whole exome sequencing can better predict treatment response

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