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Deleting single gene in gut bacteria affects metabolism, reduces weight gain in mice

Scientists have found that deleting a single gene in a particular strain of gut bacteria causes changes in metabolism and reduced weight gain in mice, according to a study in the journal eLife.

18 Jul 2018

Review: Omega 3 supplements do not reduce risk of heart disease, stroke or death

New evidence published today shows there is little or no effect of omega 3 supplements on our risk of experiencing heart disease, stroke or death.

18 Jul 2018

Fish consumption associated with lower risk of early death

Consumption of fish and long-chain omega-3 fatty acids was associated with lower risks of early death in a Journal of Internal Medicine study.

18 Jul 2018

Can-Fite BioPharma receives Australian and Chinese patents for new drug to treat erectile dysfunction

Can-Fite BioPharma Ltd., a biotechnology company advancing a pipeline of proprietary small molecule drugs that address liver diseases, inflammatory diseases and sexual dysfunction, today announced that the Australian and Chinese patent offices have granted the Company a patent for the utilization of A3 adenosine receptor ligands in the treatment of sexual dysfunction, in a patent (Australian, No. 2013301125ZL, Chinese No. 2013800472970) titled, "A3 adenosine receptor ligands for use in treatment of a sexual dysfunction."

17 Jul 2018

Study highlights potential of fetal gene therapy to prevent lethal neurodegenerative disease

A fatal neurodegenerative condition known as Gaucher disease can be prevented in mice following fetal gene therapy, finds a new study led by UCL, the KK Women's and Children's Hospital and National University Health System in Singapore.

16 Jul 2018

Non-surgical management found to be feasible option for penetrating kidney trauma

Trauma is the sixth leading cause of death worldwide, and recent studies suggest that 16 percent of renal trauma occurs from a penetrating injury, such as a gunshot wound, stabbing or piercing injury from a car accident.

16 Jul 2018

Researchers describe key role of enzyme in regulating immune response against Chagas disease parasite

In an article published recently in the journal Nature Communications, researchers affiliated with the University of São Paulo in Brazil describe the central role played by an enzyme called phosphatidylinositol 3-kinase gamma in regulating the immune response against Trypanosoma cruzi, the protozoan parasite that causes Chagas disease.

16 Jul 2018

Researchers create vaccine that protects against malaria in mouse models

A Yale-led team of researchers have created a vaccine that protects against malaria infection in mouse models, paving the way for the development of a human vaccine that works by targeting the specific protein that parasites use to evade the immune system.

13 Jul 2018

Researchers find experimental compound to treat fibrotic diseases

Normal scar tissue forms to heal an internal wound and quietly retreats when the job is done. But in many common diseases - kidney, liver and lung fibrosis -- the scar tissue goes rogue and strangles vital organs. These diseases are largely untreatable and ultimately fatal.

13 Jul 2018

Study uncovers possible link between iron loading, alcohol intake and mortality

Drinking heavily results in uncontrolled iron absorption into the body, putting strain on vital organs and increasing the risk of death, according to a new study published in the journal Clinical Nutrition.

12 Jul 2018

Olfactory receptors perform a range of unknown functions outside the nose, reveals study

A review of more than 200 studies reveals that olfactory receptors--proteins that bind to odors that aid the sense of smell--perform a wide range of mostly unknown functions outside the nose.

12 Jul 2018

Study: Hepatitis C vaccine could drastically reduce transmission among injecting drug users

Among the most serious consequences of the opioid epidemic is the spread of hepatitis C among injecting drug users.

12 Jul 2018

American Cancer Society outlines vision for cancer control in the decades ahead

The American Cancer Society is outlining its vision for cancer control in the decades ahead in a series of articles that begins publishing today.

11 Jul 2018

Researchers use genome editing to reduce cholesterol levels in animal model

Using genome editing to inactivate a protein called PCSK9 effectively reduces cholesterol levels in rhesus macaques, a species of monkey, according to researchers from the Perelman School of Medicine at the University of Pennsylvania.

10 Jul 2018

Spread of pancreatic cancer to the liver or lungs depends on plasticity of tumor cells

Pancreatic cancer often spreads, forming metastases in the liver or lungs. The prognosis is better for patients with metastases in the lungs.

9 Jul 2018

Researchers develop simple blood test to predict likely spread of rare cancer

New QUT research has shed fresh light on how head and neck cancer spreads to other organs and researchers are developing a simple blood test to tell doctors which patients are at risk of spread long before conventional imaging can.

9 Jul 2018

Researchers use gene therapy to cure obesity and type 2 diabetes in mice

A research team from the UAB led by Professor Fatima Bosch has managed to cure obesity and type 2 diabetes in mice using gene therapy.

9 Jul 2018

CTI BioPharma announces Phase III results of PIXUVRI combined with rituximab in aggressive B-cell NHL patients

CTI BioPharma Corp. and Servier today announced that the pivotal Phase III study evaluating PIXUVRI® combined with rituximab in comparison to gemcitabine combined with rituximab in patients with aggressive B-cell non-Hodgkin lymphoma did not meet its primary endpoint of improvement of progression-free survival

9 Jul 2018

Researchers focus on mechanisms involved in development of non-alcoholic fatty liver disease

One of the lines of research of the UPV/EHU's Lipids & Liver group, which focusses on the mechanisms involved in the development and progression of non-alcoholic fatty liver disease, is achieving significant advances in a range of aspects; these include the identification of proteins that alter the metabolic pathways in the development and progression of liver disease, and even cancer, and the seeking of targets to enable the disease to be reversed.

9 Jul 2018

State prisons fail to offer cure to 144,000 inmates with deadly hepatitis C

State prisons across the U.S. are failing to treat at least 144,000 inmates who have hepatitis C, a curable but potentially fatal liver disease, according to a recent survey and subsequent interviews of state corrections departments.

9 Jul 2018

Liver News and Research

Deleting single gene in gut bacteria affects metabolism, reduces weight gain in mice

Review: Omega 3 supplements do not reduce risk of heart disease, stroke or death

Fish consumption associated with lower risk of early death

Can-Fite BioPharma receives Australian and Chinese patents for new drug to treat erectile dysfunction

Study highlights potential of fetal gene therapy to prevent lethal neurodegenerative disease

Non-surgical management found to be feasible option for penetrating kidney trauma

Researchers describe key role of enzyme in regulating immune response against Chagas disease parasite

Researchers create vaccine that protects against malaria in mouse models

Researchers find experimental compound to treat fibrotic diseases

Study uncovers possible link between iron loading, alcohol intake and mortality

Olfactory receptors perform a range of unknown functions outside the nose, reveals study

Study: Hepatitis C vaccine could drastically reduce transmission among injecting drug users

American Cancer Society outlines vision for cancer control in the decades ahead

Researchers use genome editing to reduce cholesterol levels in animal model

Spread of pancreatic cancer to the liver or lungs depends on plasticity of tumor cells

Researchers develop simple blood test to predict likely spread of rare cancer

Researchers use gene therapy to cure obesity and type 2 diabetes in mice

CTI BioPharma announces Phase III results of PIXUVRI combined with rituximab in aggressive B-cell NHL patients

Researchers focus on mechanisms involved in development of non-alcoholic fatty liver disease

State prisons fail to offer cure to 144,000 inmates with deadly hepatitis C

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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