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Low oxygen levels harm specific cells in the developing brain

Low oxygen levels are a well-known cause of brain injury in premature babies. But the mechanism by which low oxygen hurts the developing human brain has been unclear.

6 May 2019

MIT researchers develop novel method for analyzing massive cell datasets

Data-sampling method makes "sketches" of unwieldy biological datasets while still capturing the full diversity of cell types.

3 May 2019

Innovative 'gut-on-a-chip' technology will help better understand Crohn's disease

To model human health and disease, organ-on-a-chip technology mimics the human body's organ structure, functionality and physiology in a controlled environment.

3 May 2019

Study asks patients’ input for improving hospital care

American hospitals engage in continuous quality and safety improvement, but information remains scarce on what patients, families and caregivers themselves most want to change about their hospital experiences.

3 May 2019

Genetic test for low birth weight on the horizon

Researchers have successfully identified 190 genetic factors associated with a low birth weight. They hope that this may one day be used to develop a universal genetic test.

3 May 2019

Discovery of small-molecule inhibitors could enable precise control over CRISPR-Cas9 genome editing

The discovery of the first small-molecule inhibitors of the Streptococcus pyogenes Cas9 (SpCas9) protein could enable more precise control over CRISPR-Cas9-based genome editing, researchers report May 2 in the journal Cell.

3 May 2019

Novel chemical probe enables live imaging of brain immune cells

Researchers in South Korea and Singapore have, for the first time, developed a chemical probe that enables live-imaging of a type of immune cells in the brain, known as microglia, in a live animal brain.

3 May 2019

Potential stem cell therapies moving from lab bench to clinical application

Stem cell research is leading to potential new therapies to treat disease, with several applications in clinical trials or expected to enter trials in the coming months.

3 May 2019

Rutgers study: Depression increases hospital use and mortality in children

Children with depression admitted to the hospital for other illnesses like pneumonia, appendicitis or seizure disorders, stay longer, pay more and are at greater risk of death, a Rutgers New Jersey Medical School study finds.

2 May 2019

Mount Sinai study provides fresh insights into cellular pathways that cause cancer

Mount Sinai researchers have broken new ground in the understanding of the MDM2 gene--which is often overexpressed in cancer--finding that when it acts with a specific protein, it can lead to cancer cell death.

2 May 2019

A new strategy for managing diabetic macular edema in people with good vision

A change to the approach for treating diabetic macular edema may be on the way, thanks to a study published today in the Journal of the American Medical Association.

2 May 2019

Children under 3 years old are most vulnerable to the effects of adversity, study finds

A Massachusetts General Hospital study has found evidence that children under 3 years old are most the vulnerable to the effects of adversity - experiences including poverty, family and financial instability, and abuse - on their epigenetic profiles, chemical tags that alter gene expression and may have consequences for future mental health.

1 May 2019

Study casts new light into how mothers' and babies' genes influence birth weight

The largest study of its kind has led to new insights into the complex relationships surrounding how mothers' and babies' genes influence birth weight.

1 May 2019

Diabetes drug could help with smoking cessation

Phillip Robinson has gone from 10 cigarettes a day to one or two every other day after enrolling in a smoking cessation clinical trial launched by researchers at The University of Texas Health Science Center at Houston

30 Apr 2019

Researchers find potential link between autism and antidepressant use during pregnancy

An international team led by Duke-NUS Medical School has found a potential link between autistic-like behavior in adult mice and exposure to a common antidepressant in the womb.

30 Apr 2019

Angiotensin receptor blockers could improve response to cancer immunotherapy

A research team led by investigators at Massachusetts General Hospital and the Massachusetts Institute of Technology has found that combining a specialized version of an antihypertension drug with immune checkpoint blockers could increase the effectiveness of cancer immunotherapies.

30 Apr 2019

Researchers use structural biology techniques to understand how lipids bind proteins

Normal cells have a complex system of checks and balances that regulate cell division.

30 Apr 2019

First GWAS for Type 2 diabetes in youth reveals seven genetic variants associated with the disease

Pediatric diabetes and genetic researchers with the First Genome-Wide Association Study (GWAS) for Type 2 diabetes in youth said they discovered seven genetic variants associated with the disease in young people.

30 Apr 2019

Multigene test helps doctors to make effective treatment decisions for breast cancer patients

A breast cancer test has been found that helps doctors make treatment decisions for some breast cancer patients, following research carried out at Queen Mary University of London and funded by Cancer Research UK.

30 Apr 2019

Women pay more for over-the-counter facial moisturizing products, MGH study finds

Over-the-counter facial moisturizers are a widely-used and commonly recommended skin care product, but a new study from dermatologists at Massachusetts General Hospital finds that, when it comes to price, men's and women's products are not considered equal.

29 Apr 2019

Medical School News and Research

Low oxygen levels harm specific cells in the developing brain

MIT researchers develop novel method for analyzing massive cell datasets

Innovative 'gut-on-a-chip' technology will help better understand Crohn's disease

Study asks patients’ input for improving hospital care

Genetic test for low birth weight on the horizon

Discovery of small-molecule inhibitors could enable precise control over CRISPR-Cas9 genome editing

Novel chemical probe enables live imaging of brain immune cells

Potential stem cell therapies moving from lab bench to clinical application

Rutgers study: Depression increases hospital use and mortality in children

Mount Sinai study provides fresh insights into cellular pathways that cause cancer

A new strategy for managing diabetic macular edema in people with good vision

Children under 3 years old are most vulnerable to the effects of adversity, study finds

Study casts new light into how mothers' and babies' genes influence birth weight

Diabetes drug could help with smoking cessation

Researchers find potential link between autism and antidepressant use during pregnancy

Angiotensin receptor blockers could improve response to cancer immunotherapy

Researchers use structural biology techniques to understand how lipids bind proteins

First GWAS for Type 2 diabetes in youth reveals seven genetic variants associated with the disease

Multigene test helps doctors to make effective treatment decisions for breast cancer patients

Women pay more for over-the-counter facial moisturizing products, MGH study finds

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

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