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Genetic twist in gallstone disease may shield against heart attacks

Mendelian randomization suggests gallstone disease may lower heart attack risk; genetics play a key role in this protective effect.

5 Nov 2023

Atlas of cancer's hidden rules: Unveiling the transcriptomic and epigenetic secrets across 11 tumors

Researchers have mapped the complex epigenetic and transcriptomic landscape of cancer, revealing key regulatory elements across 11 tumor types that could unlock new insights into cancer progression and metastasis.

5 Nov 2023

New atlas of fetal kidney reveals cell trajectories and disease signatures

Scientists have examined the gene expression patterns of single cells from 5 human fetal kidneys to create the most complete atlas of the fetal kidney to date.

3 Nov 2023

Researchers pioneer a novel treatment for the most common autoimmune encephalitis

Researchers at DZNE and Charité - Universitätsmedizin Berlin have pioneered a novel treatment for the most common autoimmune encephalitis.

3 Nov 2023

Nutrition and aging: A two-way relationship

With so much hype in the media about miracle diets and nutritional supplements, one is invariably tempted to look for a single, food-based magic bullet that will increase the likelihood of living a longer, healthier life.

3 Nov 2023

Time-lapsed images show how magnesium ions coordinate double-stranded breaks in CRISPR-Cas9

The gene-editing technology known as CRISPR has led to revolutionary changes in agriculture, health research and more.

2 Nov 2023

Study reveals how formaldehyde alters gene expression through epigenetics

Epigenetics, the chemical mechanisms that controls the activity of genes, allows our cells, tissues and organs to adapt to the changing circumstances of the environment around us.

2 Nov 2023

Gene discovery sheds light on ovary development

Researchers at the Francis Crick Institute and the Université Cote d'Azur, together with other labs in France and Switzerland, have identified a gene which is an early determining factor of ovary development in mice.

2 Nov 2023

Scientists decode genetic programs controlling sex-specific organ development

The development of sex-specific characteristics is frequently seen in mammals. These characteristics stem from the activation of corresponding genetic programs that until now have been largely undescribed by the scientific community.

2 Nov 2023

New "clickable" pseudoviruses could revolutionize virus research

Pseudoviruses resemble impostors: although harmless, they are designed in such a way that they can hardly be distinguished from their dangerous relatives. This makes them an invaluable tool in virus research.

2 Nov 2023

Gene editing breakthrough could offer new hope for people with phenylketonuria

Phenylketonuria (PKU) is a rare newborn genetic disease that impacts between 1 in 10,000 to 1 in 20,000 people, depending on the individuals' genetic ancestry. PKU causes an amino acid - called phenylalanine (Phe) - to build up in the bloodstream.

2 Nov 2023

UH researcher awarded $1.2 million grant to unravel mystery of Z-RNA

University of Houston Assistant Professor of Biology and Biochemistry Quentin Vicens has been awarded a $1.2 million grant from the National Institute of General Medical Sciences to unravel the mystery of Z-RNA – an enigmatic RNA structure within our cells that plays a critical role in immune response.

2 Nov 2023

New virus diagnosis device gives lab-quality results within just three minutes

A virus diagnosis device that gives lab-quality results within just three minutes has been invented by engineers at the University of Bath, who describe it as the 'world's fastest Covid test'.

2 Nov 2023

LHPP gene identified as a potential target for treatment-resistant depression

Major depressive disorder (MDD) is a widespread mental health condition that for many is disabling. It has long been appreciated that MDD has genetic as well as environmental influences.

2 Nov 2023

Study uncovers how sex differences emerge and evolve in animals

Researchers at the Francis Crick Institute and Heidelberg University in Germany have shown that sex differences in animals vary dramatically across species, organs and developmental stages, and evolve quickly at the gene level but slowly at the cell type level.

2 Nov 2023

Science, Innovation, and Xenotransplantation: A Discussion with Dr. Wenning Qin

In this interview, we delve deep into the pioneering world of xenotransplantation and the evolving landscape of gene editing.

2 Nov 2023

PacBio announces HiFi Solves, a global consortium of clinical genomics research leaders

PacBio (NASDAQ: PACB), a leading developer of high-quality, highly accurate sequencing solutions, today announced the creation of the HiFi Solves consortium.

From PacBio 2 Nov 2023

Cancer neuroscience: A new frontier in cancer treatment

Cancer cells hijack normal biological processes, allowing them to multiply. For example, tumors spur construction of new blood vessels, building themselves "highways" to supply nutrients.

1 Nov 2023

Highly sensitive blood test shows promise for early detection of common deadly cancers

Most cancers become deadly by keeping a low profile, causing no symptoms until they're too advanced to treat. Ovarian and gastroesophageal cancers are among the most notorious for this sly disease progression, often leading to late-stage diagnoses.

1 Nov 2023

Study shows link between mobile phone use and semen quality of young men

Does electromagnetic radiation emitted by mobile phones affect semen quality? While various environmental and lifestyle factors have been proposed to explain the decline in semen quality observed over the last fifty years, the role of mobile phones has yet to be demonstrated.

1 Nov 2023