Adenocarcinoma News and Research

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Adenocarcinoma is cancer that begins in cells that line certain internal organs and that have gland-like (secretory) properties.

HPV vaccine for girls gets thumbs up from Cochrane review

According to a Cochrane review that was released recently, the HPV vaccine, that can protect girls and young women from Human Papilloma virus (HPV) can help protect them against cancer of the cervix later in life. The report appears in the latest issue of the Cochrane Database of Systematic Reviews.

13 May 2018

Centrosome amplification may contribute to initiation of cancers, research suggests

Cells begin to accumulate centrosomes - organelles that play a vital role during cell division - before they transform into cancer cells, according to a new study of patients with Barrett's esophagus condition, which is associated with esophageal cancer.

8 May 2018

Researchers develop novel theranostic procedure for treating ductal pancreatic adenocarcinoma

German researchers have developed a novel diagnostic and therapeutic (theranostic) procedure for patients with ductal pancreatic adenocarcinoma, a deadly cancer with an extremely poor prognosis (five-year survival rate of less than 5 percent) and limited treatment options. The study is featured in the May issue of The Journal of Nuclear Medicine.

2 May 2018

Lymph node status after preoperative therapy determines survival of esophageal cancer patients

According to a new study, the status of lymph nodes rather than the status of the primary tumor following preoperative neoadjuvant chemotherapy or chemoradiation therapy is the most important factor that determines whether patients with locally advanced esophageal cancer will survive.

2 May 2018

Innovative research could lead to new ways to treat, prevent cancer

Research into cancer can provide new insight into how this disease works and how it can be stopped. The Experimental Biology 2018 meeting will showcase innovative research that could lead to new ways to treat and prevent cancer.

23 Apr 2018

Finding ways to reverse obesity’s lingering, pro-cancer effects

Like exposure to too much sun and drinking alcohol, obesity is a risk factor for cancer. Researchers at the University of North Carolina Lineberger Comprehensive Cancer Center are working to be a part of the solution -- they want to find ways to reverse obesity-linked biological changes in the body that are associated with cancer growth.

16 Apr 2018

Novel biomarker helps optimize anticancer therapy

Researchers have identified a biomarker that can be used to visualize blood vessel activity and optimize the timing of anticancer therapy.

9 Apr 2018

Vascular stabilization biomarker helps optimize timing of anticancer therapies

Angiogenesis, the formation of new blood vessels, is essential for tumor growth. A new study reported in The American Journal of Pathology describes a vascular stabilization biomarker that can visualize blood vessel activity, thus optimizing the timing of anticancer therapies including anti-angiogenics.

9 Apr 2018

New guideline on use of endoscopic eradication therapy in Barrett's esophagus

The latest issue of GIE: Gastrointestinal Endoscopy, the official journal of the American Society for Gastrointestinal Endoscopy, includes a new society guideline on use of endoscopic eradication therapy Barrett's esophagus.

6 Apr 2018

Gut microbiome may promote pancreatic cancer by inducing immune suppression

Bacterial load was significantly higher in pancreatic tumor samples from patients with pancreatic ductal adenocarcinoma compared with pancreatic tissue from normal individuals, and in studies using mice, eliminating certain "bad" bacteria slowed the growth of pancreatic cancer, reversed immune suppression, and upregulated the immune checkpoint protein PD1.

22 Mar 2018

Researcher working to develop improved endoscopic probe for colonoscopies

Tim Muldoon, assistant professor of biomedical engineering, has received a $500,000 Faculty Early Career Development Program award from the National Science Foundation to continue his work on an endoscopic probe that can be used in colonoscopies.

14 Mar 2018

New study finds that thirdhand smoke increases lung cancer risk in mice

Researchers at the Department of Energy's Lawrence Berkeley National Laboratory (Berkeley Lab) identified thirdhand smoke, the toxic residues that linger on indoor surfaces and in dust long after a cigarette has been extinguished, as a health hazard nearly 10 years ago.

9 Mar 2018

Modifying Oncolytic Adenoviruses to Target Pancreatic Cancer

Pancreatic cancer is one of the less common but deadliest cancers. Modified oncolytic adenoviruses represent an alternative to chemotherapy and targeted therapies, which have a high mortality rate.

9 Mar 2018

Researchers seek to discover role of filter ventilation on addictive potential of cigarettes

Would banning ventilated filters on cigarettes protect public health? Scientists from multiple institutions, including a group of addiction neuroscience researchers from the Virginia Tech Carilion Research Institute, are gathering evidence under funding from the National Institutes of Health's National Cancer Institute to potentially inform a U.S. Food and Drug Administration (FDA) decision about whether to recommend design changes to filtered cigarettes.

7 Mar 2018

Scientists move closer to developing alternative method for breast cancer detection

Engineering researchers at the University of Arkansas have moved closer to developing an alternative method of detecting and possibly treating breast cancer.

2 Mar 2018

Researchers explore how evolutionary processes guide pathways of cells

Evolution describes how all living forms cope with challenges in their environment, as they struggle to persevere against formidable odds. Mutation and selective pressure--cornerstones of Darwin's theory--are the means by which organisms gain an advantageous foothold or pass into oblivion.

23 Feb 2018

Expert panel releases updated guidelines for lung cancer molecular testing

Lung cancer treatment often pairs targeted therapies with genetic alterations driving the disease. This makes detecting these genetic alterations an essential step in diagnosis.

30 Jan 2018

Sugar-attaching enzyme found to be abundant in colon cancer cells

Researchers have identified an enzyme that is absent in healthy colon tissue but abundant in colon cancer cells, according to a report in the Jan. 26 issue of the Journal of Biological Chemistry.

27 Jan 2018

Leading medical societies update molecular testing guideline for lung cancer

Rapid advancements in the molecular diagnostic testing of lung cancer have led to new treatments and greater hope for patients battling lung cancer, the most common cause of cancer death worldwide.

24 Jan 2018

Biomarkers may help predict prognosis of gastric cancer patients with alcohol consumption habits

Alcohol consumption has been identified as a modifiable risk factor for cancers such as gastric cancer. A new report in the The American Journal of Pathology sheds light on how specific proteins interact with alcohol, and how that interplay impacts survival and response to platinum-based adjuvant chemotherapy in patients with gastric cancer who may or may not still be drinking.

10 Jan 2018