Immunization News and Research

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How did population immunity against SARS-CoV-2 infection and subsequent severe disease change between December 2021 and November 2022?

Researchers explored the alterations in population immunity against SARS-CoV-2 Omicron variant infection and severe disease.

23 Nov 2022

The safety and immunogenicity of a fourth dose of NVX-CoV2373

Researchers assessed the immunogenicity and safety of a fourth homologous boost dose of a recombinant SARS-CoV-2 spike protein vaccine called NVX-CoV2373.

23 Nov 2022

Myocarditis after COVID vaccination is rare but higher in younger males

In a recent study published in the Canadian Medical Association Journal, researchers observed the incidence of myocarditis following messenger ribonucleic acid (mRNA)-based vaccination against coronavirus disease 2019 (COVID-19). Additionally, they compared their estimates with expected rates based on the historical rates assessed before the COVID-19 vaccination rollout in British Columbia (BC), Canada.

22 Nov 2022

Approved and developing passive and active immunizations against respiratory syncytial virus in childhood and pregnancy

Researchers explored active and passive vaccination among children against respiratory syncytial virus (RSV).

22 Nov 2022

Chitin-immobilized nanobodies for SARS-CoV-2 detection

Researchers demonstrated a novel strategy to detect SARS-CoV-2 using chitin-immobilized nanobodies.

21 Nov 2022

When is it best to use dose-sparing vaccination strategies for monkeypox to protect more people?

Researchers evaluated dose-sparing strategies for monkeypox (MPX) vaccination using mathematical modeling.

17 Nov 2022

Jynneos vaccine for Monkeypox not linked to hospitalization, serious cardiac events

In a recent study posted to the medRxiv* preprint server, researchers investigated the incidence of cardiac AESIs (adverse events of special interest) among Kaiser Permanente Northwest (KPNW) members who had received JYNNEOS vaccinations against the monkeypox (MPX) virus.

16 Nov 2022

Development of a potent, broadly protective vaccine against all SARS-CoV-2 variants

In a recent study published in the journal npj Vaccines, researchers in China designed, produced, and evaluated the neutralization efficacy of a recombinant coronavirus disease 2019 (COVID-19) vaccine containing four hot-spot substitution mutations based on a prefusion-stabilized severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein (S) trimer.

15 Nov 2022

SARS-CoV-2 transmission among asymptomatic cases is lower

In a recent study published in the BMC Medicine journal, researchers at the Norwegian Institute of Public Health explored severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission among asymptomatic cases.

15 Nov 2022

Five important things to know about polio

Public Health authorities have warned health care workers to be on the alert for polio, yet most physicians will not be familiar with presentation of this highly infectious, life-threatening disease.

15 Nov 2022

Hemagglutinin stem immunogens may hold the key for broad protection against influenza A viruses

Researchers proposed that vaccines targeting the immunosubdominant yet conserved hemagglutinin (HA) stem could trigger broadly neutralizing antibodies (bnAbs) against influenza A viruses.

15 Nov 2022

Study reveals the heavy burden of RSV among healthy infants

A new study in The Lancet Respiratory Medicine journal aimed to determine hospitalized and medically-attended RSV-associated respiratory infections in healthy infants across Europe.

14 Nov 2022

Moderna's bivalent boosters trigger strong antibody response against latest subvariants

Moderna reports the efficacy of a bivalent COVID-19 vaccine booster dose.

14 Nov 2022

A novel mRNA-based vaccine candidate against the rabies virus

Scientists have developed a novel mRNA-based vaccine candidate against the rabies virus. The vaccine induces a strong antibody response and exhibits high protective efficacy against lethal rabies infection in mice and dogs. A full report about the vaccine has been published in the Virology Journal.

14 Nov 2022

SARS-CoV-2 spike subunit conformation determines plasma-neutralizing activity triggered by COVID-19 vaccines and natural infection

In a new study, researchers evaluated the effect of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) glycoprotein conformation on S-directed neutralizing antibodies (nAbs).

14 Nov 2022

More adverse reactions following bivalent COVID-19 mRNA booster vaccine

A recent study posted to medRxiv* examined adverse reactions after administration of a bivalent BNT162b2 coronavirus disease 2019 (COVID-19) vaccine booster.

13 Nov 2022

Omicron BA.1/BA.2 breakthrough infection after 3-dose BNT162b2 vaccination provides improved protection against Omicron BA.5

In a recent study published in the Emerging Infectious Disease journal, researchers compared the neutralization associated with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron BA.5 sublineage to Omicron BA.1/BA.2 sublineages among vaccinated and convalescent patients.

13 Nov 2022

Mosaic nanoparticles displaying spike protein trimers from different coronaviruses elicits cross-reactive protection

In a recent study under review at the Nature Portfolio journal and currently posted to Research Square* preprint server, researchers developed and assessed the immunogenicity of nanoparticles expressing spike trimers from coronaviruses (CoVs).

10 Nov 2022

The comparative risk of myocarditis, pericarditis, and myopericarditis between BNT162b2 and mRNA-1273 second doses

Researchers assessed the risk of myocarditis or pericarditis after the COVID-19 mRNA vaccine second doses.

10 Nov 2022

What is the role of adenoviruses in human health?

With advances in molecular biology informing recent developments in vaccinology, gene therapy, and other fields of medicine, human adenoviruses (HAdVs) have been of primary importance in medical research. A recent review looks at the promises of HAdVs, their potential dangers, and future challenges.

9 Nov 2022

Immunization News and Research

How did population immunity against SARS-CoV-2 infection and subsequent severe disease change between December 2021 and November 2022?

The safety and immunogenicity of a fourth dose of NVX-CoV2373

Myocarditis after COVID vaccination is rare but higher in younger males

Approved and developing passive and active immunizations against respiratory syncytial virus in childhood and pregnancy

Chitin-immobilized nanobodies for SARS-CoV-2 detection

When is it best to use dose-sparing vaccination strategies for monkeypox to protect more people?

Jynneos vaccine for Monkeypox not linked to hospitalization, serious cardiac events

Development of a potent, broadly protective vaccine against all SARS-CoV-2 variants

SARS-CoV-2 transmission among asymptomatic cases is lower

Five important things to know about polio

Hemagglutinin stem immunogens may hold the key for broad protection against influenza A viruses

Study reveals the heavy burden of RSV among healthy infants

Moderna's bivalent boosters trigger strong antibody response against latest subvariants

A novel mRNA-based vaccine candidate against the rabies virus

SARS-CoV-2 spike subunit conformation determines plasma-neutralizing activity triggered by COVID-19 vaccines and natural infection

More adverse reactions following bivalent COVID-19 mRNA booster vaccine

Omicron BA.1/BA.2 breakthrough infection after 3-dose BNT162b2 vaccination provides improved protection against Omicron BA.5

Mosaic nanoparticles displaying spike protein trimers from different coronaviruses elicits cross-reactive protection

The comparative risk of myocarditis, pericarditis, and myopericarditis between BNT162b2 and mRNA-1273 second doses

What is the role of adenoviruses in human health?

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