Metabolic Disorders News and Research

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Study shows how aging fat cells lead to lifestyle diseases

No matter how much we try and fight it, aging is a part of life. High cholesterol, diabetes, and fatty liver, the collection of conditions referred to as lifestyle diseases, all become more commonplace as we get older.

18 Aug 2020

Combination of gout and diabetes carries increased risk of amputation

Diabetes mellitus and gout are ranked among the most common metabolic disorders in Western industrialised countries: According to figures published by the World Health Organization (WHO), around 60 million Europeans suffer from diabetes (2) and 18 million Europeans suffer from gout (3).

13 Aug 2020

Genomic sequencing falls short as a standalone screening tool for newborns

With the rise of genomic sequencing, health technology companies are promising parents they can detect rare metabolic disorders in newborns who, despite a healthy appearance, may need immediate treatment.

10 Aug 2020

Researchers develop scalable strategy to find novel molecular glue degraders

Despite enormous efforts to advance traditional pharmacology approaches, more than three quarters of all human proteins remain beyond the reach of therapeutic development.

4 Aug 2020

Study: ANGEL2 enzyme performs unique chemical reaction at the end of RNA molecules

Scientists led by Javier Martinez from the Max Perutz Labs, a joint venture of the Medical University of Vienna and the University of Vienna, have identified a unique chemical reaction at the end of RNA molecules for the first time in human cells.

31 Jul 2020

Study offers new possibilities for developing anti-aging drugs

KAIST researchers have been able to dial up and down creatures' lifespans by altering the activity of proteins found in roundworm cells that tell them to convert sugar into energy when their cellular energy is running low.

31 Jul 2020

Is medication exposing us to hormone-disrupting chemicals?

News-Medical speaks to Dr. Robert M. Sargis about his research into whether medication is exposing us to hormone-disrupting chemicals.

28 Jul 2020

Research will help improve diagnosis of disease in newborn babies from urine samples

New research will help health-care practitioners to more accurately diagnose disease and illness in newborn babies from urine samples, according to a study by researchers at the University of Alberta and the Universidad Autónoma de Zacatecas.

16 Jul 2020

Umbilical cord blood safely and effectively treats children with rare genetic disorders

Researchers at UPMC Children's Hospital of Pittsburgh found that infusing umbilical cord blood - a readily available source of stem cells - safely and effectively treated 44 children born with various non-cancerous genetic disorders, including sickle cell, thalassemia, Hunter syndrome, Krabbe disease, metachromatic leukodystrophy (MLD) and an array of immune deficiencies.

14 Jul 2020

Genomic sequencing to provide precision medicine for aromatase deficiency

An international team of scientists from Switzerland Spain, has studied the genetic basis of aromatase deficiency, a rare metabolic disorder that prevents the production of estrogens in humans, according to new research in JCEM.

30 Jun 2020

Novel vaccine that removes aged immune cells mitigates metabolic disorders in obese mice

Aging is a multifaceted process that affects our bodies in many ways. In a new study, researchers from Osaka University developed a novel vaccine that removes aged immune cells and then demonstrated an improvement of diabetes-associated metabolic derangements by vaccinating obese mice.

30 Jun 2020

Study identifies new gene variants tied to type-2 diabetes

After examining the genes of more than 200,000 people all over the world who have type-2 diabetes, researchers from the Perelman School of Medicine at the University of Pennsylvania and the Veterans Health Administration's Corporal Michael J. Crescenz Veterans Affairs Medical Center found hundreds of genetic variants never before linked to the disease.

23 Jun 2020

Long-term endurance training alters the activity of genes involved in metabolic health

Decades-long endurance training alters the activity of genes in human skeletal muscle that are important for metabolic health.

23 Jun 2020

Researchers develop method to assess mitochondrial respiration in frozen tissues

Scientists led by Dr. Orian Shirihai, director of the metabolism theme at the David Geffen School of Medicine at UCLA, have developed a method for restoring oxygen-consumption activity to previously frozen mitochondria samples, even years after they have been collected.

23 Jun 2020

Study reveals completely new mechanism for mitochondrial disease

Researchers at Karolinska Institutet in Sweden have discovered that excessive degradation of the power plants of our cells plays an important role in the onset of mitochondrial disease in children.

11 Jun 2020

Study: Campylobacter infection is associated with child stunting

Gastrointestinal infection with Campylobacter plays a major role in the stunting of children in urban Bangladesh, say the authors of a new study.

5 Jun 2020

New data may help understand the evolution of Austrian SARS-CoV-2 strains

216 SARS-CoV-2 genome sequences have now been completed and released in the framework of the "Mutational Dynamics of SARS-CoV-2 in Austria" project from CeMM, the Research Center for Molecular Medicine of the Austrian Academy of Sciences, in close collaboration with the Medical University of Vienna, the Medical University of Innsbruck and the Austrian Agency for Health and Food Safety (AGES).

27 May 2020

Single-cell RNA-seq addresses key question in islet cell biology and diabetes research

The pancreas is an abdominal organ that produces digestive enzymes as well as hormones that regulate blood sugar levels. This hormone-producing function is localized to the islets of Langerhans, which constitute clusters of different endocrine cell types.

12 May 2020

Breastfeeding helps reduce the risk of maternal postpartum diabetes

A team of South Korean researchers found that lactation can lower the incidence and reduce the risk of maternal postpartum diabetes.

29 Apr 2020

Excess weight may cause mental fatigue, research suggests

Obesity has been shown to place physical stress on the body, but new research suggests that excess weight may also cause mental fatigue.

27 Apr 2020

Metabolic Disorders News and Research

Study shows how aging fat cells lead to lifestyle diseases

Combination of gout and diabetes carries increased risk of amputation

Genomic sequencing falls short as a standalone screening tool for newborns

Researchers develop scalable strategy to find novel molecular glue degraders

Study: ANGEL2 enzyme performs unique chemical reaction at the end of RNA molecules

Study offers new possibilities for developing anti-aging drugs

Is medication exposing us to hormone-disrupting chemicals?

Research will help improve diagnosis of disease in newborn babies from urine samples

Umbilical cord blood safely and effectively treats children with rare genetic disorders

Genomic sequencing to provide precision medicine for aromatase deficiency

Novel vaccine that removes aged immune cells mitigates metabolic disorders in obese mice

Study identifies new gene variants tied to type-2 diabetes

Long-term endurance training alters the activity of genes involved in metabolic health

Researchers develop method to assess mitochondrial respiration in frozen tissues

Study reveals completely new mechanism for mitochondrial disease

Study: Campylobacter infection is associated with child stunting

New data may help understand the evolution of Austrian SARS-CoV-2 strains

Single-cell RNA-seq addresses key question in islet cell biology and diabetes research

Breastfeeding helps reduce the risk of maternal postpartum diabetes

Excess weight may cause mental fatigue, research suggests

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