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Advancing GPCR drug discovery with fragment screening using GCI technology

Evotec's insights into GPCRs and waveRAPID technology reveal new opportunities in drug discovery, focusing on orphan receptors and innovative screening methods.

From Creoptix (A Malvern Panalytical brand) 23 May 2025

Machine learning tool identifies metabolic clues in colorectal cancer

Scientists aiming to advance cancer diagnostics have developed a machine learning tool that is able to identify metabolism-related molecular profile differences between patients with colorectal cancer and healthy people.

22 May 2025

Closed Loop Medicine appoints Kate Woolland as CEO

Closed Loop Medicine Ltd. (“CLM”), a leader in pharmaceutical precision dosing, today announced the appointment of Kate Woolland as Chief Executive Officer.

22 May 2025

Mount Sinai researchers explore new depression treatment targeting brain’s potassium channels

A mechanism involving potassium channels in the brain that control brain cell activity could provide a new and fundamentally different way of treating depression symptoms in adults with major depressive disorder, according to two complementary papers published recently by researchers at the Icahn School of Medicine at Mount Sinai.

21 May 2025

Perceptive eclinical launches Clinphone Pro: An innovative RTSM platform built by RTSM experts for RTSM experts

Perceptive eClinical unveils ClinPhone Pro, a next-generation RTSM platform. Built on over 30 years of experience, ClinPhone Pro integrates seamlessly within the clinical technology ecosystem, offering advanced drug supply simulation and rolling forecast capabilities.

From Perceptive 21 May 2025

Air pollution exposure in pregnancy may increase asthma risk for the next generation

A mother's exposure to air pollution during pregnancy can increase asthma risk in her adult offspring, according to a new mouse study published at the ATS 2025 International Conference.

20 May 2025

CN Bio expands access to OOC solutions for APAC customers with distributor agreement in South Korea

CN Bio, a leading provider of Organ-on-a-chip (OOC) systems and solutions that accelerate drug discovery and development workflows, today announced a strategic partnership with SCINCO, a specialist scientific instrument company based in South Korea.

20 May 2025

NELL2 identified as a key regulator of bone formation and fat suppression

A recent study identifies Neural EGFL-like 2 (NELL2), a secreted protein, as a key regulator of bone homeostasis, offering potential therapeutic applications for osteoporosis.

19 May 2025

Genomic study of non-Hispanic Black veterans with prostate cancer yields key insights for precision medicine

In the largest clinical genomic profiling study of non-Hispanic Black men with metastatic prostate cancer to date, researchers from Moffitt Cancer Center, University of Pennsylvania, University of California Los Angeles and the Veterans Affairs (VA) National Precision Oncology Program found key differences in tumor biology between non-Hispanic Black and non-Hispanic white veterans, but similar survival outcomes when both groups had equal access to care.

16 May 2025

Floral diversity supports honeybee survival through winter

Especially in temperate climates, winter poses a major challenge for honeybee colonies. To ensure their survival, the animals must maintain the right temperature in the hive and raise the next generation of workers.

16 May 2025

Optimer licensing agreements and repeat custom

Aptamer Group plc, the leading developer of next-generation synthetic binders delivering innovation to the life science industry, has announced two new development contracts for Optimer binders and the agreement of licensing heads of terms with a global provider of specialty enzymes for developed enzyme-modulating Optimers.

From Aptamer Group 16 May 2025

Aptamer announces new data at ASGCT

Aptamer Group plc, the leading developer of next-generation synthetic binders delivering innovation to the life science industry, presented new data on its Optimer therapeutic delivery vehicle for liver fibrosis at the American Society of Gene and Cell Therapy (ASGCT) Annual Meeting in New Orleans, LA (13-17 May 2025).

From Aptamer Group 16 May 2025

HIV vaccine study marks breakthrough in targeting broad immune responses

A decades-long scientific challenge in HIV vaccine development has been finding a way to train the immune system to produce antibodies that can target many variants of the virus.

15 May 2025

Next generation module improves flow process automation

Vapourtec has recently unveiled their Reaction Controller and Datalogger Module which improves the automation of flow chemistry experiments by enabling automated control and logging when using third-party pumps, recirculators, flow meters, sensors and balances.

14 May 2025

New insights into HIV-1 capsid disruption open doors for novel therapies

Announcing a new publication for Acta Materia Medica journal. The HIV-1 capsid protein (CA) plays a crucial role in viral replication by orchestrating nuclear entry through interactions with host nuclear pore complexes (NPCs).

13 May 2025

Researchers unlock new paths toward treating stress-related psychiatric disorders

In a comprehensive Genomic Psychiatry review article published today, researchers from the University of Rochester Medical Center have synthesized decades of research on stress hormone systems in primate brains, potentially unlocking new paths toward treating stress-related psychiatric disorders.

13 May 2025

HER3 reemerges as a key driver of cancer progression and therapy resistance

A new publication shines a spotlight on HER3, a long-overlooked member of the ErbB receptor family, revealing its critical role in cancer progression and resistance to therapy.

12 May 2025

Tirzepatide outperforms semaglutide in weight loss clinical trial

Tirzepatide (trade name Zepbound) promoted greater weight loss in individuals with obesity than did semaglutide (trade name Wegovy) in a clinical trial that compared the safety and efficacy of the injectable drugs.

12 May 2025

Breakthrough discovery offers hope for treating neurodegenerative diseases

Researchers have discovered how to block cells dying, in a finding that could lead to new treatments for neurodegenerative conditions like Parkinson's and Alzheimer's.

12 May 2025

PhoreMost makes key appointments to Board to advance development of next-generation degrader therapeutics

PhoreMost Ltd., a next-generation targeted protein degradation (TPD) company progressing a pipeline of degrader therapeutics within oncology and inflammation, today announced Barbara Duncan has joined its Board as Chair, and Stephen Dilly as Non-Executive Director.

From PhoreMost 12 May 2025

Next Generation News and Research

Advancing GPCR drug discovery with fragment screening using GCI technology

Machine learning tool identifies metabolic clues in colorectal cancer

Closed Loop Medicine appoints Kate Woolland as CEO

Mount Sinai researchers explore new depression treatment targeting brain’s potassium channels

Perceptive eclinical launches Clinphone Pro: An innovative RTSM platform built by RTSM experts for RTSM experts

Air pollution exposure in pregnancy may increase asthma risk for the next generation

CN Bio expands access to OOC solutions for APAC customers with distributor agreement in South Korea

NELL2 identified as a key regulator of bone formation and fat suppression

Genomic study of non-Hispanic Black veterans with prostate cancer yields key insights for precision medicine

Floral diversity supports honeybee survival through winter

Optimer licensing agreements and repeat custom

Aptamer announces new data at ASGCT

HIV vaccine study marks breakthrough in targeting broad immune responses

Next generation module improves flow process automation

New insights into HIV-1 capsid disruption open doors for novel therapies

Researchers unlock new paths toward treating stress-related psychiatric disorders

HER3 reemerges as a key driver of cancer progression and therapy resistance

Tirzepatide outperforms semaglutide in weight loss clinical trial

Breakthrough discovery offers hope for treating neurodegenerative diseases

PhoreMost makes key appointments to Board to advance development of next-generation degrader therapeutics

Advancing Intracellular Delivery with LumiPore®

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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