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Older heart muscle cells accumulate new genetic mutations -; while losing the ability to repair them

Why does the risk of heart disease go up as we age? Known risk factors such as hypertension or high cholesterol don't explain all cases.

12 Aug 2022

Remdesivir activates urotensin II receptor and induces cardiomyocyte dysfunction

In newly released research, scientists assessed the cardiac effects of remdesivir.

12 Aug 2022

Study highlights the urgent need for combinatorial drug therapies for SARS-CoV-2

Researchers investigated the susceptibility of naturally-occurring severe acute respiratory syndrome coronavirus 2 main protease variants to protease inhibitor drugs, including nirmatrelvir and ensitrelvir.

11 Aug 2022

Nearly three-quarters of all stem cell lines are affected by DNA damage, say researchers

DNA damage caused by factors such as ultraviolet radiation affect nearly three-quarters of all stem cell lines derived from human skin cells, say Cambridge researchers, who argue that whole genome sequencing is essential for confirming if cell lines are usable.

11 Aug 2022

Pathogens in ancient DNA could explain how two civilizations collapsed

The current study has strongly indicated the presence of Y. pestis and S. enterica on the island of Crete that contributed to societal changes during 2,000 BCE.

9 Aug 2022

Researchers unravel a novel molecular target of eicosapentaenoic acid

Eicosapentaenoic acid (EPA) is an essential nutrient belonging to the omega-3 group of polyunsaturated fatty acids (PUFAs). As the human body cannot synthesize PUFAs, dietary supplements containing EPA are required for normal physiological functions. Found abundantly in natural sources like fish, hemp oil, and linseed oil, EPA is known to exhibit anti-inflammatory, neuroprotective, and cardiovascular protective activities.

9 Aug 2022

New dual-plasmid editing system for DNA-based information rewriting in vivo

DNA-based information is a new interdisciplinary field linking information technology and biotechnology.

5 Aug 2022

Analysis of monkeypox virus genomes suggests that it spread early and cryptically

A new study reports the identification of a cluster of monkeypox virus A.2 lineage genomes.

3 Aug 2022

Children with intellectual disability of genetic origin are extremely likely to develop other neuropsychiatric conditions

A major study of children with intellectual disabilities has highlighted the additional challenges that they often face, including a much-increased likelihood of being diagnosed as autistic, as well as Attention Deficit Hyperactivity Disorder (ADHD) and other mental health difficulties.

3 Aug 2022

New and efficient method Monkeypox virus sequencing

In a recent study posted to the medRxiv* preprint server, Spanish researchers described a new enrichment method for metagenomic sequencing of the monkeypox virus (MPXV).

2 Aug 2022

Predicting viral antibody escape using pre-pandemic data

A new study reports early prediction of SARS-CoV-2 immune evasion using EVEscape.

28 Jul 2022

New research points to multiple zoonotic origins of SARS-CoV-2

In a new study, researchers demonstrated that SARS-CoV-2 zoonotic spillover to humans involved two separate cross-species transmission events and lineages A and B viruses.

28 Jul 2022

Does vaccine- or infection-induced immunity protect less well against infection by specific SARS-CoV-2 variants?

Researchers found that vaccinated people were at an increased risk of infection with SARS-CoV-2 Beta, Gamma, or Delta variants.

28 Jul 2022

Genetic variations in one serotonin receptor could be the reason behind psychedelic treatment disparity

When all else fails, some patients trying to overcome alcoholism, severe depression or anxiety, and even cluster headaches, turn to psychedelic drugs, which clinical research has shown can help treat individuals with these conditions, sometimes with dramatically positive results.

27 Jul 2022

Genetic variations in serotonin receptor causes different response to psychedelic drugs

Cluster headaches, anxiety and depression can be debilitating for people living with these conditions. Psychedelic drugs have shown benefits as treatments for these conditions in clinical studies, but not for everyone.

27 Jul 2022

Researchers assess UK biobank genome sequences

In a new study, researchers analyzed 150,119 genome sequences from the United Kingdom Biobank (UKB).

26 Jul 2022

How prepared are we for a widespread monkeypox outbreak?

In a new study, researchers summarized the epidemiology, etiology, clinical presentation, diagnosis and prevention and treatment strategies for monkeypox (MPX) caused by the monkeypox virus (MPXV).

25 Jul 2022

Is monkeypox a global public-health emergency?

A summary of available knowledge on the monkeypox virus including pathogenicity, risk to the human population, and strategies that can help limit its spread.

20 Jul 2022

Adopting a healthy cardiovascular lifestyle may lower stroke risk

Genes and lifestyle factors together play a role in stroke risk. However, even for people at high risk for stroke, adopting a healthy cardiovascular lifestyle may significantly lower the risk of stroke in their lifetime, according to new research published today in the Journal of the American Heart Association, an open access, peer-reviewed journal of the American Heart Association.

20 Jul 2022

Identifying a core human microbiome

Researchers provide a critical review of the concept of the core human microbiome.

19 Jul 2022

Nucleotide News and Research

Older heart muscle cells accumulate new genetic mutations -; while losing the ability to repair them

Remdesivir activates urotensin II receptor and induces cardiomyocyte dysfunction

Study highlights the urgent need for combinatorial drug therapies for SARS-CoV-2

Nearly three-quarters of all stem cell lines are affected by DNA damage, say researchers

Pathogens in ancient DNA could explain how two civilizations collapsed

Researchers unravel a novel molecular target of eicosapentaenoic acid

New dual-plasmid editing system for DNA-based information rewriting in vivo

Analysis of monkeypox virus genomes suggests that it spread early and cryptically

Children with intellectual disability of genetic origin are extremely likely to develop other neuropsychiatric conditions

New and efficient method Monkeypox virus sequencing

Predicting viral antibody escape using pre-pandemic data

New research points to multiple zoonotic origins of SARS-CoV-2

Does vaccine- or infection-induced immunity protect less well against infection by specific SARS-CoV-2 variants?

Genetic variations in one serotonin receptor could be the reason behind psychedelic treatment disparity

Genetic variations in serotonin receptor causes different response to psychedelic drugs

Researchers assess UK biobank genome sequences

How prepared are we for a widespread monkeypox outbreak?

Is monkeypox a global public-health emergency?

Adopting a healthy cardiovascular lifestyle may lower stroke risk

Identifying a core human microbiome

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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