Pathophysiology News and Research

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Profound neuroinflammation associated with long COVID

Around 36 to 53% of coronavirus disease 2019 (COVID-19) patients develop persistent chronic symptoms, often referred to as long COVID or PASC.

7 Jun 2022

Stem cell model could provide insights into biological mechanisms that underlie neuropsychiatric disorders

Researchers from the Icahn School of Medicine at Mount Sinai have applied a novel stem cell model to map disease risk variants in human neurons, which could help provide insights into the biological mechanisms that underlie neuropsychiatric disorders such as autism and schizophrenia.

1 Jun 2022

Scientists determine trajectory and pathophysiology of post-COVID-19 syndrome

A new study utilizes multisystem imaging, along with biomarker analysis, to better understand the pathogenesis of COVID-19.

30 May 2022

Using diffusion-weighted MRI to visualize brain inflammation in vivo for the first time

Research of the laboratories led by Dr. Silvia de Santis and Dr. Santiago Canals, both from the Institute of Neurosciences UMH-CSIC (Alicante, Spain), has made it possible to visualize for the first time and in great detail brain inflammation using diffusion-weighted Magnetic Resonance Imaging.

27 May 2022

The root causes of long-COVID still a mystery

In a recent article posted to the journal Annals of Internal Medicine, researchers presented baseline outcomes from a longitudinal assessment of post-acute sequelae of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection (PASC), also known as long-COVID.

25 May 2022

Researchers propose new imaging method to study neural networks in living brains

The brain is made up of a complex series of networks-signals are constantly bouncing between those networks to allow us to experience the world and move through it effectively.

25 May 2022

Largest study to date on long COVID identifies a broad list of diagnoses

Researchers characterize post-acute sequelae of SARS-CoV-2 infection.

25 May 2022

Ohio University to launch a summer program focused on diabetes research for undergraduate students

A summer program for undergraduate students who plan to pursue a graduate or medical degree related to diabetes research will be launched at Ohio University in 2023 thanks to support from a prestigious National Institutes of Health Research Education Program (R25) grant.

24 May 2022

Even safe levels of alcohol consumption may harm the heart

Levels of alcohol consumption currently considered safe by some countries are linked with development of heart failure, according to research presented at Heart Failure 2022, a scientific congress of the European Society of Cardiology.

22 May 2022

Comparison of COVID-induced ARDS and sepsis-induced ARDS

In a recent study posted to the medRxiv* preprint server, researchers compared the pathophysiology of coronavirus disease 2019 (COVID-19) and bacterial sepsis-induced acute respiratory distress syndrome (ARDS).

20 May 2022

COVID-19's impact on sex and fertility

The potential effects of SARS-CoV-2 on sexual activity and fertility.

20 May 2022

Preclinical study may pave the way toward prevention and recovery of neonatal brain injuries

The findings of a new pre-clinical study published in The Journal of Neuroscience are helping pave the way toward better understanding, prevention and recovery of neonatal brain injuries.

19 May 2022

Blood adenosine levels positively correlate to the white matter lesions in very low birth weight premature infants

Prematurity affects about 10% of pregnancies worldwide each year. In about 20% of very low birth weight (VLBW) premature infants, punctate white matter lesions (PWML) can be diagnosed at MRI at term equivalent age.

13 May 2022

The Future of Gynecological Conditions; Improving Attention, Understanding, and Treatment

In this interview, News-Medical talks to Dr. Laurence Orbuch about the lack of understanding behind gynecological conditions like endometriosis and how this needs to change.

13 May 2022

Approximately 13% of hospitalized COVID patients have serious neurologic symptoms

In a recent study in the journal Critical Care Explorations, the Viral Infection and Respiratory Illness Universal Study (VIRUS): COVID-19 Registry was used to record significant neurologic signs of SARS-CoV-2 infection, as well as prehospital risk factors and outcomes.

9 May 2022

Exploring vitamin D and acute COVID-19 infection

Researchers assessed the presence of vitamin D deficiency in COVID-19-recovered patients

6 May 2022

miRNAs associated with varying clinical presentations of SARS-CoV-2

A recent article published in the journal iSCIENCE demonstrated different micro ribonucleic acids (miRNAs) linked with various presentations of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections.

5 May 2022

Free SARS-CoV-2 spike protein fragments may trigger platelet activation and clot formation in COVID-19

In a recent study under review in the Nature Portfolio journal and currently available on the Research Square* preprint server, researchers investigated the presence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein (SP) in the thrombi (or blood clots).

5 May 2022

Oral Nirmatrelvir's effects on long COVID symptoms

In a recent study posted to the Research Square* preprint server, researchers at the University of California, San Francisco, examined the cases of three individuals who received nirmatrelvir/ritonavir antiviral therapy at different stages following severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.

4 May 2022

Genetic risk score has potential to improve prevention of severe knee and hip osteoarthritis

A research team has developed a risk score based on individuals' genetic data to predict their likelihood of needing hip or knee replacement surgery for osteoarthritis.

4 May 2022

Pathophysiology News and Research

Profound neuroinflammation associated with long COVID

Stem cell model could provide insights into biological mechanisms that underlie neuropsychiatric disorders

Scientists determine trajectory and pathophysiology of post-COVID-19 syndrome

Using diffusion-weighted MRI to visualize brain inflammation in vivo for the first time

The root causes of long-COVID still a mystery

Researchers propose new imaging method to study neural networks in living brains

Largest study to date on long COVID identifies a broad list of diagnoses

Ohio University to launch a summer program focused on diabetes research for undergraduate students

Even safe levels of alcohol consumption may harm the heart

Comparison of COVID-induced ARDS and sepsis-induced ARDS

COVID-19's impact on sex and fertility

Preclinical study may pave the way toward prevention and recovery of neonatal brain injuries

Blood adenosine levels positively correlate to the white matter lesions in very low birth weight premature infants

The Future of Gynecological Conditions; Improving Attention, Understanding, and Treatment

Approximately 13% of hospitalized COVID patients have serious neurologic symptoms

Exploring vitamin D and acute COVID-19 infection

miRNAs associated with varying clinical presentations of SARS-CoV-2

Free SARS-CoV-2 spike protein fragments may trigger platelet activation and clot formation in COVID-19

Oral Nirmatrelvir's effects on long COVID symptoms

Genetic risk score has potential to improve prevention of severe knee and hip osteoarthritis

Industry Focus eBook - Forensics & toxicology (2nd edition) eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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