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CCC study provides hope that SapC-DOPS could be used for metastatic brain cancer treatment

Over half of patients being seen in the clinic for a diagnosed brain tumor have metastatic cancer, which has no treatment and detrimental outcomes in most cases.

25 Jul 2014

Study identifies molecular mechanisms could lead to new therapies to treat obesity, diabetes

A protein that controls when genes are switched on or off plays a key role in specific areas of the brain to regulate metabolism, UT Southwestern Medical Center researchers have found.

25 Jul 2014

Protein once seen as promising anti-cancer compound helps to stabilize neural circuits

Researchers at UC San Francisco (UCSF) have discovered that endostatin, a protein that once aroused intense interest as a possible cancer treatment, plays a key role in the stable functioning of the nervous system.

25 Jul 2014

Immune system play role in memory impairment associated with chronic epilepsy

Could the body's own immune system play a role in memory impairment and cognitive dysfunction associated with conditions like chronic epilepsy, Alzheimer's dementia and concussions? Cleveland Clinic researchers believe so, based on a study published online by PLOS ONE.

25 Jul 2014

New method allows chemist to use X-rays to look deep into biological samples

It is seldom sufficient to read the declaration of contents if you need to know precisely what substances a product contains.

25 Jul 2014

Compounds developed for cancer treatment show promise as potential oral therapy for Alzheimer's

Currently, no cure exists for Alzheimer's disease, the devastating neurological disease affecting more than 5 million Americans. But scientists are now reporting new progress on a set of compounds, initially developed for cancer treatment, that shows promise as a potential oral therapy for Alzheimer's. Their study appears in ACS' Journal of Medicinal Chemistry.

24 Jul 2014

Researchers uncover how malaria parasite becomes resistant to fosmidomycin drug

Researchers have uncovered a way the malaria parasite becomes resistant to an investigational drug. The discovery, at Washington University School of Medicine in St. Louis, also is relevant for other infectious diseases including bacterial infections and tuberculosis.

24 Jul 2014

George Mason University researchers use dyes to paint new picture of diseases

By using brightly hued dyes, George Mason University researchers discovered an innovative way to reveal where proteins touch each other, possibly leading to new treatments for cancer, arthritis, heart disease and even lung disease.

24 Jul 2014

Dynamic nuclear polarization: an interview with Professor Robert Griffin, Massachusetts Institute of Technology

DNP, or dynamic nuclear polarization, is an NMR technique which transfers polarization from the electron spins onto the nuclear spins, using constant microwave irradiation to enable the transfer.

From Bruker BioSpin Group 24 Jul 2014

Scientists work to detect chronic traumatic encephalopathy in earliest stages

Autopsies have shown that some high-profile athletes who suffered repeated blows to the head during their careers have unusual protein clumps in their brains.

24 Jul 2014

CRIPTO1 role in TKI resistance elucidated

Overexpression of CRIPTO1 may explain intrinsic tyrosine kinase inhibitor resistance in around 10% of patients with non-small-cell lung cancer and endothelial growth factor receptor mutations, research indicates.

23 Jul 2014

More genetic suspects for schizophrenia brought to light

A meta-analysis from the Schizophrenia Working Group of the Psychiatric Genomics Consortium has revealed a large number of previously unreported genetic loci that may have a role in schizophrenia.

23 Jul 2014

Vanderbilt-led research team identifies protein "signatures" that drive colorectal cancer

A Vanderbilt University-led research team has identified protein "signatures" of genetic mutations that drive colorectal cancer, the nation's second leading cause of cancer deaths after lung cancer.

23 Jul 2014

New research sheds light on genetic basis for heart disease in women

When it comes to heart disease, Dr. Ross Feldman says women are often in the dark. Historically, it was thought that heart disease was a men's-only disease, however, data has shown that post-menopausal women are just as likely as men to get heart disease and are less likely to be adequately diagnosed and treated.

23 Jul 2014

Study explores how changes in dopamine transporter function linked to brain disorders

Recent published research in the Journal of Clinical Investigation demonstrates how changes in dopamine signaling and dopamine transporter function are linked to neurological and psychiatric diseases, including early-onset Parkinsonism and attention deficit hyperactivity disorder (ADHD).

23 Jul 2014

Study reveals novel epilepsy pathway linked to neurodegenerative diseases

A recent scientific discovery showed that mutations in prickle genes cause epilepsy, which in humans is a brain disorder characterized by repeated seizures over time. However, the mechanism responsible for generating prickle-associated seizures was unknown.

23 Jul 2014

Signs and symptoms of Lewy body dementia

"I watched my husband experience a decline in cognition followed by a period of what seemed like improved function only to plunge again into confusion with more frequent hallucinations," says one caregiver newly acquainted with Lewy body dementia (LBD).

22 Jul 2014

G Protein News and Research

CCC study provides hope that SapC-DOPS could be used for metastatic brain cancer treatment

Study identifies molecular mechanisms could lead to new therapies to treat obesity, diabetes

Protein once seen as promising anti-cancer compound helps to stabilize neural circuits

Immune system play role in memory impairment associated with chronic epilepsy

New method allows chemist to use X-rays to look deep into biological samples

Compounds developed for cancer treatment show promise as potential oral therapy for Alzheimer's

Researchers uncover how malaria parasite becomes resistant to fosmidomycin drug

George Mason University researchers use dyes to paint new picture of diseases

Dynamic nuclear polarization: an interview with Professor Robert Griffin, Massachusetts Institute of Technology

Scientists work to detect chronic traumatic encephalopathy in earliest stages

CRIPTO1 role in TKI resistance elucidated

More genetic suspects for schizophrenia brought to light

Vanderbilt-led research team identifies protein "signatures" that drive colorectal cancer

New research sheds light on genetic basis for heart disease in women

Study explores how changes in dopamine transporter function linked to brain disorders

Study reveals novel epilepsy pathway linked to neurodegenerative diseases

Signs and symptoms of Lewy body dementia

Researchers prove that CD27 drug is true alternative against malaria

New molecules and biopharmaceuticals enhance patient's immune response against tumors

Study shows inactivation of p53 protein promotes cancer progression

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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