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Scientists show how specialized cells help each other survive under stress

A team led by scientists from the Florida campus of The Scripps Research Institute and the University of Pittsburgh has shown for the first time how one set of specialized cells survives under stress by manipulating the behavior of key immune system cells.

4 Nov 2015

Elderly women should take more vitamin D supplementation during the wintertime, suggests researchers

Osteoporosis is one of the chief reasons why the elderly often suffer broken bones from relatively minor injuries. Postmenopausal women in particular experience a relatively rapid loss in bone mass due to a reduced concentration of oestrogen, which is responsible for strong bone growth during youth. Maintaining bone mass requires physical exercise and vitamin D, which is mainly produced in the skin with the help of UVB radiation. This is why, especially in the wintertime, many elderly women are prescribed a vitamin D supplement by their doctor to maintain bone mass.

4 Nov 2015

Chemotherapy treatment can contribute to long-term neurocognitive deficits in pediatric brain tumor survivors

More children are surviving malignant brain tumors than in the past, thanks to the use of intense treatments using platinum-based chemotherapy (cisplatin and high-dose carboplatin). Unfortunately, the therapy has a known side effect of permanent hearing loss, resulting from damage to the inner ear.

4 Nov 2015

Scientists propose that Alzheimer's disease should be treated separately

Deciphering the mechanism that underlies the development of Alzheimer's disease in certain families but not in others, researchers at the Hebrew University of Jerusalem's Faculty of Medicine have proposed that the malady is actually a collection of diseases that probably should be treated with a variety of different approaches.

4 Nov 2015

UCSD researchers suggest that cancer-related mutations common in patients with low blood counts

Patients with unexplained low blood counts and abnormally mutated cells who do not fit the diagnostic criteria for recognized blood cancers should be described as having clonal cytopenias of undetermined significance (CCUS), suggest University of California, San Diego School of Medicine researchers in a recent paper published in the journal Blood.

4 Nov 2015

TUM researchers uncover signaling pathways that play vital role in self-renewal of blood stem cells

Stem cells have two important capabilities: they can develop into a wide range of cell types and simultaneously renew themselves, creating fresh stem cells. Using a model of the blood forming (hematopoietic) system, researchers at the Technical University of Munich have now been able to precisely determine, which signaling pathways play an essential role in the self-renewal of blood stem cells.

4 Nov 2015

Northeastern University researchers create 3-D printing technology to develop patient-specific products

A team of researchers at Northeastern University has developed an innovative 3-D printing technology that uses magnetic fields to shape composite materials--mixes of plastics and ceramics--into patient-specific products. The biomedical devices they are developing will be both stronger and lighter than current models and, with their customized design, ensure an appropriate fit.

4 Nov 2015

Samumed to present preclinical and clinical data on Wnt pathway for OA treatment at ACR 2015

Samumed, LLC, a leader in tissue regeneration, announced today that it will present preclinical and clinical data on a small molecule modulator of the Wnt pathway (SM04690, an investigational new drug) for potential disease modifying treatment of osteoarthritis (OA) of the knee at 2015 American College of Rheumatology Annual Meeting.

4 Nov 2015

Blood stem cell self-renewal dependent on surroundings

Stem cells have two important capabilities: they can develop into a wide range of cell types and simultaneously renew themselves, creating fresh stem cells. Using a model of the blood forming (hematopoietic) system, researchers at the Technical University of Munich (TUM) have now been able to precisely determine, which signaling pathways play an essential role in the self-renewal of blood stem cells. A particularly decisive role in this process is the interactive communication with surrounding tissue cells in the bone marrow.

3 Nov 2015

Approval to start trial of Videregen's replacement trachea technology

The INSPIRE consortium, led by Videregen Ltd, has received approval from the MHRA1 to start a UK clinical trial with its tissue engineered replacement trachea.

3 Nov 2015

$Older people with age-related muscle loss face greater risk of falls, bone fractures$

Older people with age-related muscle loss face greater risk of falls, bone fractures

Older people with an age-related loss of muscle mass and strength may be at greater risk of falling and bone fractures, according to new research led by the University of Southampton.

3 Nov 2015

$Viking begins VK5211 Phase 2 trial in patients recovering from hip fracture$

Viking begins VK5211 Phase 2 trial in patients recovering from hip fracture

Viking Therapeutics, Inc., a clinical-stage biopharmaceutical company focused on the development of novel, first-in-class or best-in-class therapies for metabolic and endocrine disorders, today announced the initiation of dosing in the company's Phase 2 clinical trial of VK5211 in patients who recently suffered a hip fracture.

3 Nov 2015

Diet rich in soy protein and isoflavones can protect menopausal women from osteoporosis

Eating a diet rich in both soy protein and isoflavones can protect menopausal women from bone weakening and osteoporosis, according to the results of a preliminary study presented today at the Society for Endocrinology annual conference in Edinburgh.

2 Nov 2015

Key protein controls stem cell properties that could make them useful in regenerative medicine

A key protein controls stem cell properties that could make them more useful in regenerative medicine, according to a study led by Mount Sinai researchers and published online today in the journal Cell Stem Cell.

31 Oct 2015

Penn Medicine's Gordon Baltuch performs 1,000th deep brain stimulation procedure

Deep brain stimulation (DBS) improves many of the motor symptoms of Parkinson's disease (PD) and is a life-alerting surgery for many patients. Penn Medicine's Gordon Baltuch, MD, a professor of Neurosurgery and director of the Penn Center for Functional and Restorative Neurosurgery, is one of the most prolific DBS surgeons in the world, having recently performed his 1,000th procedure, marking an important milestone for Baltuch and Penn Medicine.

31 Oct 2015

New campaign raises awareness of City of Hope's life-saving mission and impact

Imagine being diagnosed with one of the most rare and aggressive forms of breast cancer, given a five percent chance to live and told having children will never be an option. Southern California local Kommah McDowell was told just that— and then she went to City of Hope.

31 Oct 2015

World’s first mini synchrotron inaugurated at Technical University of Munich

For some years now it has been possible to generate high-brilliance X-rays using ring-shaped particle accelerators. However, such installations are several hundred meters in diameter and cost billions of euros.

31 Oct 2015

Stem cell transplantation may offer viable treatment for Alzheimer's disease patients

Alzheimer's disease (AD), affecting millions worldwide, is the leading cause of dementia. The prevalence of AD is rapidly increasing, and will possibly affect over 100 million people by 2050, yet there are no effective therapies for the disease.

31 Oct 2015

Specialized type of immunotherapy can boost survival from pancreatic cancer

A new study in mice by researchers at Fred Hutchinson Cancer Research Center has found that a specialized type of immunotherapy — even when used without chemotherapy or radiation — can boost survival from pancreatic cancer, a nearly almost-lethal disease, by more than 75 percent. The findings are so promising, human clinical trials are planned within the next year.

30 Oct 2015

Vertical jump could predict lower body bone strength in adolescents

Every year at least 250,000 older Americans are hospitalized for hip fractures. It is hard to recover from a hip fracture, and many people lose their independence afterward. Low bone strength during the growing the years can lead to a greater chance of having a hip fracture as an older adult.

30 Oct 2015

Bone News and Research

Scientists show how specialized cells help each other survive under stress

Elderly women should take more vitamin D supplementation during the wintertime, suggests researchers

Chemotherapy treatment can contribute to long-term neurocognitive deficits in pediatric brain tumor survivors

Scientists propose that Alzheimer's disease should be treated separately

UCSD researchers suggest that cancer-related mutations common in patients with low blood counts

TUM researchers uncover signaling pathways that play vital role in self-renewal of blood stem cells

Northeastern University researchers create 3-D printing technology to develop patient-specific products

Samumed to present preclinical and clinical data on Wnt pathway for OA treatment at ACR 2015

Blood stem cell self-renewal dependent on surroundings

Approval to start trial of Videregen's replacement trachea technology

Older people with age-related muscle loss face greater risk of falls, bone fractures

Viking begins VK5211 Phase 2 trial in patients recovering from hip fracture

Diet rich in soy protein and isoflavones can protect menopausal women from osteoporosis

Key protein controls stem cell properties that could make them useful in regenerative medicine

Penn Medicine's Gordon Baltuch performs 1,000th deep brain stimulation procedure

New campaign raises awareness of City of Hope's life-saving mission and impact

World’s first mini synchrotron inaugurated at Technical University of Munich

Stem cell transplantation may offer viable treatment for Alzheimer's disease patients

Specialized type of immunotherapy can boost survival from pancreatic cancer

Vertical jump could predict lower body bone strength in adolescents

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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