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ROS1 fusion genes found in young East Asian patients with lung adenocarcinoma

ROS1 fusion genes were successfully detected independent of gender or smoking history in young East Asian patients with lung adenocarcinoma, a histological subgroup in non-small cell lung cancer (NSCLC), using multiplex reverse transcriptase-polymerase chain reaction (RT-PCR) and immunohistochemistry (IHC) diagnostic tests.

22 Jul 2014

Elevated ASM activity linked to Alzheimer's disease

Unclogging the body's protein disposal system may improve memory in patients with Alzheimer's disease (AD), according to a study from scientists at Kyungpook National University in Korea published in The Journal of Experimental Medicine.

22 Jul 2014

New chromatin immunoprecipitation sequencing kit developed by Porvair Sciences

Porvair Sciences has developed a new ChIP sequencing assay kit extending the benefits of their proprietary Chromatrap® solid state ChIP technology to preparation of purified Chromatin for the generation of sequencing libraries.

From Chromatrap® - Porvair Sciences Ltd 22 Jul 2014

First diagnostic criteria proposed for Christianson Syndrome

Because the severe autism-like condition Christianson Syndrome was only first reported in 1999 and some symptoms take more than a decade to appear, families and doctors urgently need fundamental information about it. A new study that doubles the number of cases now documented in the scientific literature provides the most definitive characterization of CS to date.

22 Jul 2014

Beckman announces national availability of Prostate Health Index

Beckman Coulter Diagnostics, a global leader in prostate cancer diagnostics, announces national availability of the Prostate Health Index (phi)*, a simple, non‐invasive blood test that is three times more specific in detecting prostate cancer1 than PSA (prostate‐specific antigen).

22 Jul 2014

Unnatural DNA bases: an interview with Professor Floyd E. Romesberg, The Scripps Research Institute

The natural DNA bases that form the letters of DNA are usually referred to as G, C, A, and T. Those are only the first letters of the chemical names. They’re often called nucleotides by their scientific name and all of them have in common a phosphate part, a sugar part and a nucleobase part.

21 Jul 2014

A personalized approach for patients with ccRCC-related mutations

In an analysis of small molecules called metabolites used by the body to make fuel in normal and cancerous cells in human kidney tissue, a research team from the Perelman School of Medicine at the University of Pennsylvania identified an enzyme key to applying the brakes on tumor growth.

21 Jul 2014

Study reveals new invasion mechanism of Enterovirus 71

A new study determines glycosylation and pH-dependent conformational changes of virus receptor SCARB2 as crucial for EV71 attachment, entry and uncoating.

21 Jul 2014

IL-10 enhances positive benefits of transplanted allogenic SMCs to repair cardiac tissues after MI

The long-term, positive benefits of transplanted allogenic (other-donated) smooth muscle cells (SMCs) to repair cardiac tissues after myocardial infarction (MI) have been enhanced by the addition of interleukin 10 (IL-10) to the transplanted cells, report researchers in Canada.

21 Jul 2014

Sciatic nerve injury can cause differential expression of microRNAs in dorsal root ganglia

Slit-Robo GTPase-activating protein 3 contains a Rho GAP domain that regulates the activities of Rho family GTPases and affects actin polymerization, which influences dendrite elaboration, neurite outgrowth and axon guidance, contributing to neural regeneration.

21 Jul 2014

New molecular analysis tool to detect targets for immunotherapy in early-stage breast cancers

Yale Cancer Center researchers used a new molecular analysis tool to accurately detect the level of an important target for immunotherapy in early-stage breast cancers.

21 Jul 2014

Enhancing autophagy in pre-diabetic patients has potential to prevent onset of diabetes

Diabetes affects almost 400 million people worldwide. One of the hallmarks of this disease is a loss of pancreatic β cells, which secrete insulin. In many patients the reduction of β cells is associated an accumulation of a toxic form of a protein produced by β cells, known as islet amyloid polypeptide.

21 Jul 2014

Researchers identify group of cells in brain that plays important role in Down syndrome

Researchers from UC Davis School of Medicine and Shriners Hospitals for Children - Northern California have identified a group of cells in the brain that they say plays an important role in the abnormal neuron development in Down syndrome.

21 Jul 2014

Scientists reveal structure of protein involved in life and development of cancer

Scientists reveal the structure of one of the most important and complicated proteins in cell division - a fundamental process in life and the development of cancer - in research published in Nature today (Sunday).

21 Jul 2014

Scientists make seminal breakthrough in understanding molecular basis of fibroadenoma

A multi-disciplinary team of scientists from the National Cancer Centre Singapore, Duke-NUS Graduate Medical School Singapore, and Singapore General Hospital have made a seminal breakthrough in understanding the molecular basis of fibroadenoma, one of the most common breast tumours diagnosed in women.

21 Jul 2014

Learning role of immune-system cells in digestive tracts may lead to new treatments for IBS

Learning the role of immune-system cells in healthy digestive tracts and how they interact with neighboring nerve cells may lead to new treatments for irritable bowel syndrome (IBS).

18 Jul 2014

UT Southwestern researcher named recipient of ASBMB Merck Award for research on molecular biology

Dr. Zhijian "James" Chen, Professor of Molecular Biology and a Howard Hughes Medical Institute investigator at UT Southwestern Medical Center, has been named the 2015 recipient of the American Society for Biochemistry and Molecular Biology Merck Award, which recognizes outstanding contributions to research in biochemistry and molecular biology.

18 Jul 2014

G Protein News and Research

ROS1 fusion genes found in young East Asian patients with lung adenocarcinoma

Elevated ASM activity linked to Alzheimer's disease

New chromatin immunoprecipitation sequencing kit developed by Porvair Sciences

First diagnostic criteria proposed for Christianson Syndrome

Beckman announces national availability of Prostate Health Index

Unnatural DNA bases: an interview with Professor Floyd E. Romesberg, The Scripps Research Institute

A personalized approach for patients with ccRCC-related mutations

Study reveals new invasion mechanism of Enterovirus 71

IL-10 enhances positive benefits of transplanted allogenic SMCs to repair cardiac tissues after MI

Sciatic nerve injury can cause differential expression of microRNAs in dorsal root ganglia

New molecular analysis tool to detect targets for immunotherapy in early-stage breast cancers

Enhancing autophagy in pre-diabetic patients has potential to prevent onset of diabetes

Researchers identify group of cells in brain that plays important role in Down syndrome

Scientists reveal structure of protein involved in life and development of cancer

Scientists make seminal breakthrough in understanding molecular basis of fibroadenoma

Learning role of immune-system cells in digestive tracts may lead to new treatments for IBS

UT Southwestern researcher named recipient of ASBMB Merck Award for research on molecular biology

IWGSC publishes draft sequence of bread wheat genome

Role of immune system cells in healthy digestive tracts may lead to new treatments for IBS

FDA approves Ruconest for treatment of acute attacks in adolescent patients with HAE

Industry Focus eBook - Forensics & toxicology (2nd edition) eBook

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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