Clinical Trial News and Research

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ACTG initiates clinical trial to evaluate treatment for COVID-19

The AIDS Clinical Trials Group, the world's largest and longest established HIV research network, today announced the initiation of ACTG 5395, a clinical trial to evaluate whether the drug combination hydroxychloroquine and azithromycin can prevent hospitalization and death from COVID-19 (which is caused by infection with the virus SARS-CoV-2).

14 May 2020

11 healthcare centers participate in clinical trial of Russian drug against novel coronavirus

Initially, the drug was developed to treat rheumatoid arthritis. BIOCAD developers receive regulatory authorization as part of the procedure approved by Decree No. 441 of the Government of the Russian Federation of April 4, 2020 since the mechanism of action of the active substance is associated with the cytokine storm, a life-threatening immune system response in patients with COVID-19.

14 May 2020

Potential targets discovered for COVID-19 therapy

A team of biochemists and virologists at Goethe University and the Frankfurt University Hospital were able to observe how human cells change upon infection with SARS-CoV-2, the virus causing COVID-19 in people.

14 May 2020

Lessons for COVID-19 from 2009 H1N1

The world has experienced many outbreaks of viral diseases. Over the past two decades, we have also seen the emergence of zoonotic human respiratory coronaviruses with pandemic potential.

13 May 2020

New treatment improves survival for people with common liver cancer

For the first time in over a decade, scientists have identified a first-line treatment that significantly improves survival for people with hepatocellular carcinoma, the most common type of liver cancer.

13 May 2020

C-Path, Provention Bio collaborate to improve scientific community's insight into type 1 diabetes

The Critical Path Institute and Provention Bio, Inc. are proud to announce their collaboration to significantly improve the scientific community's insight into type 1 diabetes through Provention's contribution of data from the Phase III Protégé study of teplizumab to the T1D Trial Outcome Measures Initiative integrated database.

13 May 2020

UCI Health to initiate clinical trial of a drug to treat critically ill COVID-19 patients

UCI Health will initiate a clinical study of a drug to treat critically ill COVID-19 patients who face a high mortality rate because of acute inflammation that fills their lungs with fluid, a grave condition that even mechanical ventilation cannot improve.

13 May 2020

Scientists discover how the iron chelator drives immune system to deal with TB

Although COVID-19 commands the headlines today, tuberculosis (TB) remains the biggest infection killer in the world and multiple drug resistant TB, which does not respond to regular antibiotics, continues to be a major threat to global health.

13 May 2020

Non-invasive ventilation mask could reduce aerosolization when treating COVID-19 patients

Led by Lawson Health Research Institute, London Health Sciences Centre, University Health Network and General Dynamics Land Systems-Canada, researchers have designed a non-invasive ventilation mask that could significantly reduce aerosolization - the production of airborne respiratory droplets that may contain viruses or bacteria - when treating patients with COVID-19.

13 May 2020

Study explores whether senicapoc drug can mitigate lung damage in COVID-19 patients

Scientists around the globe are working to identify approved and investigational drugs that can be repurposed to treat COVID-19.

13 May 2020

New project aims to create special glasses for people with keratoconus

A Fight for Sight funded research study will work to create spectacle lenses for people with the eye disease keratoconus.

13 May 2020

Researchers launch clinical trial to test the efficacy of antidepressant against COVID-19

An antidepressant medication is being tested as a potential treatment for COVID-19 after University of Virginia School of Medicine researchers determined it may prevent dangerous overreactions by the immune system.

13 May 2020

Could JAK blockers help treat COVID-19?

A new study published in the journal Science Immunology in May 2020 reports that compounds that safely inhibit the JAK protein could be useful in treating COVID-19.

12 May 2020

A 'multi-omics' approach to the development of drugs against COVID-19

A new study published on the preprint server medRxiv* in May 2020 reports a multi-omics approach that could make it easier to develop drugs that are effective against COVID-19.

12 May 2020

Clinical trial to test the efficacy of defibrotide medicine for reducing COVID-19 death rate

The Neurosciences Institute, mixed centre of the Spanish National Research Council and the Miguel Hernández University of Elche, have collaborated on the first clinical trial conducted in the world to test whether the defibrotide medicine, which has already been authorized to treat a severe obstruction of the hepatic sinusoidal veins of people who have undergone a bone marrow transplant, can be used as therapy against COVID-19.

12 May 2020

Clinical trial to evaluate two-drug immunotherapy combination in cancer patients with COVID-19

A unique two-drug immunotherapy combination first evaluated at Roswell Park Comprehensive Cancer Center as an approach for treating some cancers will soon be available to cancer patients with COVID-19 through a clinical trial at Roswell Park.

12 May 2020

COVID-19 patients improve after experimental heart cell therapy

Four of six critically ill COVID-19 (coronavirus) patients significantly improved after receiving an experimental therapeutic designed to reduce inflammation, a major cause of death from this disease, according to a case series published by Cedars-Sinai and Capricor Therapeutics.

12 May 2020

Study may reveal why some people are more affected by Covid-19 than others

A group of researchers funded by the British Heart Foundation (BHF) have set-up a clinical study of NHS Healthcare Workers to better understand the spread of coronavirus (Covid-19), and why some people are more affected by the virus than others.

12 May 2020

Clinical trial launched to evaluate experimental COVID-19 therapies

Clinical leaders from the University of Kentucky's Markey Cancer Center, College of Medicine and College of Pharmacy have launched a clinical trial for experimental therapies to treat patients infected with COVID-19.

11 May 2020

Study shows how our eyes recycle vitamin A

Many of us will remember been told as kids when we refused to eat our vegetables that 'carrots are good for your eyes'. Although our parents may not have fully understood it at the time, there is some truth to this. Carrots are a rich source of the vitamin A essential for healthy vision.

11 May 2020

Clinical Trial News and Research

ACTG initiates clinical trial to evaluate treatment for COVID-19

11 healthcare centers participate in clinical trial of Russian drug against novel coronavirus

Potential targets discovered for COVID-19 therapy

Lessons for COVID-19 from 2009 H1N1

New treatment improves survival for people with common liver cancer

C-Path, Provention Bio collaborate to improve scientific community's insight into type 1 diabetes

UCI Health to initiate clinical trial of a drug to treat critically ill COVID-19 patients

Scientists discover how the iron chelator drives immune system to deal with TB

Non-invasive ventilation mask could reduce aerosolization when treating COVID-19 patients

Study explores whether senicapoc drug can mitigate lung damage in COVID-19 patients

New project aims to create special glasses for people with keratoconus

Researchers launch clinical trial to test the efficacy of antidepressant against COVID-19

Could JAK blockers help treat COVID-19?

A 'multi-omics' approach to the development of drugs against COVID-19

Clinical trial to test the efficacy of defibrotide medicine for reducing COVID-19 death rate

Clinical trial to evaluate two-drug immunotherapy combination in cancer patients with COVID-19

COVID-19 patients improve after experimental heart cell therapy

Study may reveal why some people are more affected by Covid-19 than others

Clinical trial launched to evaluate experimental COVID-19 therapies

Study shows how our eyes recycle vitamin A

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