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Researchers unlock mystery of immunosuppressive drug's biosynthesis

Mycophenolic acid (MPA), discovered in 1893, was the first natural antibiotic to be isolated and crystallized in human history.

22 Jun 2019

New biological mechanism may explain heightened somatic awareness

An international team spearheaded by researchers at McGill University has discovered a biological mechanism that could explain heightened somatic awareness, a condition where patients experience physical discomforts for which there is no physiological explanation.

20 Jun 2019

Researchers find a potential modulator in revascularization of pancreatic islets

The first cause of the loss of functionality in transplanted pancreatic islets is the low capacity to create new vessels to allow the arrival of nutrients in the cells.

20 Jun 2019

Scientists pinpoint cause of fatal respiratory disorder that turns babies' lips and skin blue

Scientists used a gene editing method called CRISPR/Cas9 to generate mice that faithfully mimic a fatal respiratory disorder in newborn infants that turns their lips and skin blue. The new laboratory model allowed researchers to pinpoint the ailment's cause and develop a potential and desperately needed nanoparticle-based treatment.

19 Jun 2019

Creating a physical and genetic map of Cannabis sativa

Scientists have developed a physical and genetic map of Cannabis sativa to facilitate further investigation into the genetic and molecular mechanisms exhibited by this plant.

19 Jun 2019

Metabolic engineering of cannabinoids – are we there yet?

There has recently been a surge in research into the biosynthetic pathways of cannabinoids and the potential for commercialized metabolic engineering.

19 Jun 2019

Researchers discover redundancies in immune cells

Researchers at ETH Zurich have discovered redundancies in the biochemical signaling pathways of immune cells. This finding has important implications for advances in cancer immunotherapy, among other areas.

18 Jun 2019

Scientists develop new class of drugs to treat hereditary kidney disease

Scientists from the University of Sheffield are part of an international collaboration to develop a new class of drugs to treat a common genetic kidney disease which is a major cause of kidney failure.

18 Jun 2019

Duke researchers identify enzyme involved in regulating growth, spread of breast cancers

Immunotherapies have transformed cancer care, but their successes have been limited for reasons that are both complex and perplexing.

18 Jun 2019

Scientists delay aging using protein found in young mice

Scientists have shown that a protein which is abundant in the blood of young mice can delay the aging process of older mice.

17 Jun 2019

Mutant bacterial receptor could help identify therapeutic compounds that inhibit quorum sensing

Researchers have developed a new mutant version of a receptor used by a bacterial pathogen for a chemical communication process called quorum sensing, according to a study published June 13 in the open-access journal PLOS Pathogens by Bonnie Bassler of Princeton University, and colleagues.

From PLOS ONE 14 Jun 2019

Research suggests new way to improve the efficacy of arthritis drug

Attaching a removable lock to an arthritis drug can make it safer and more effective, according to a new study publishing June 13 in the open-access journal PLOS Biology led by Wen-Wei Lin of Kaohsiung Medical University, Taiwan.

From PLOS ONE 14 Jun 2019

Researchers identify effective drug combinations for malignant brain tumor in mice

Usually, scientists study the molecular biology of cancer to find new treatments, but sometimes, it is the other way round: when trying to find new treatments, scientists find key information on cancer biology.

14 Jun 2019

Ultra-Small Microelectrode Biosensors for Brain Injury Analysis

An interview with Stéphane Marinesco, discussing the development of ultra-small microelectrode biosensors for the analysis of traumatic brain injuries.

From Pittcon 14 Jun 2019

Research identifies new approach to staving off the detrimental effects of aging

New research has identified a novel approach to staving off the detrimental effects of aging, according to a study from Washington University School of Medicine in St. Louis.

14 Jun 2019

Scientists turn type A blood into universal type O, potentially doubling blood transfusion stocks

Researchers have developed a technique for turning type A blood into universal type O blood. The development could boost blood stocks dramatically.

13 Jun 2019

New technology harnesses bacterial jumping genes for precise DNA integration

A new discovery by researchers at Columbia University Vagelos College of Physicians and Surgeons could fix one of the major shortcomings of current gene-editing tools, including CRISPR, and offer a powerful new approach for genetic engineering and gene therapy.

13 Jun 2019

Research aims to use orange peels for improving heart health

You've heard an apple a day keeps the doctor away. Now orange peels may improve your heart health.

13 Jun 2019

New method produces opiate antidotes using microorganism found in opium poppy waste

Overdose from opiates has skyrocketed. According to the National Center for Health Statistics, on average, 130 Americans die every day from an opioid overdose.

12 Jun 2019

Fibrinogen a key player in health and disease, says new study

A new study from the University of Alberta demonstrated that the blood clotting protein called fibrinogen also regulates MMP-2, an enzyme involved in immunity and in clot formation inside blood vessels. Prolonged MMP-2 inhibition could potentially produce a deficiency state with severe consequences.

12 Jun 2019

Enzyme News and Research

Researchers unlock mystery of immunosuppressive drug's biosynthesis

New biological mechanism may explain heightened somatic awareness

Researchers find a potential modulator in revascularization of pancreatic islets

Scientists pinpoint cause of fatal respiratory disorder that turns babies' lips and skin blue

Creating a physical and genetic map of Cannabis sativa

Metabolic engineering of cannabinoids – are we there yet?

Researchers discover redundancies in immune cells

Scientists develop new class of drugs to treat hereditary kidney disease

Duke researchers identify enzyme involved in regulating growth, spread of breast cancers

Scientists delay aging using protein found in young mice

Mutant bacterial receptor could help identify therapeutic compounds that inhibit quorum sensing

Research suggests new way to improve the efficacy of arthritis drug

Researchers identify effective drug combinations for malignant brain tumor in mice

Ultra-Small Microelectrode Biosensors for Brain Injury Analysis

Research identifies new approach to staving off the detrimental effects of aging

Scientists turn type A blood into universal type O, potentially doubling blood transfusion stocks

New technology harnesses bacterial jumping genes for precise DNA integration

Research aims to use orange peels for improving heart health

New method produces opiate antidotes using microorganism found in opium poppy waste

Fibrinogen a key player in health and disease, says new study

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