Cholesterol News and Research

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Cholesterol is a waxy, fat-like substance made in the liver, and found in the blood and in all cells of the body. Cholesterol is important for good health and is needed for making cell walls, tissues, hormones, vitamin D, and bile acid.

Researchers discover NPC1 protein as crucial for Ebola virus to enter host cells

Although outbreaks are rare, Ebola virus, the cause of Ebola hemorrhagic fever (EHF), is one of the deadliest known viruses affecting humans. According to the World Health Organization (WHO), approximately 1,850 EHF cases with more than 1,200 deaths have been documented since the virus was identified in 1976.

25 Aug 2011

Simvastatin may reduce spinal cord damage from ischemia/reperfusion injury

The cholesterol-lowering drug simvastatin appears to reduce spinal cord injury caused by oxygen deprivation in experimental animals, according to a study in the September issue of Anesthesia & Analgesia, official journal of the International Anesthesia Research Society.

24 Aug 2011

Disturbing images and threatening anti-smoking messages can 'boomerang'

Health communicators have long searched for the most effective ways to convince smokers to quit. Now, University of Missouri researchers have found that using a combination of disturbing images and threatening messages to prevent smoking is not effective and could potentially cause an unexpected reaction.

23 Aug 2011

CHL completes $18.4-million Series B financing round

Cleveland HeartLab Inc. (CHL), a leading specialty clinical laboratory and disease management company, today announced the completion of an $18.4-million Series B financing round.

23 Aug 2011

ATGL produces key signaling molecules essential for regulation of lipid, energy metabolism

Obesity, diabetes, and cardiovascular diseases are daunting modern-day epidemics. In Western Europe more than 50% of the population is overweight and approximately 15 million people die from cardiovascular diseases such as heart attacks and stroke every year. These conditions are often caused by disorders of fat metabolism, resulting in a massive accumulation of fat in various tissues and of cholesterol in the walls of arteries.

22 Aug 2011

Calcium scores and heart disease risk, experts debate

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22 Aug 2011

Statin therapy may not be appropriate for certain patients at risk for stroke

For many patients, cholesterol-lowering statin drugs can reduce the risk of strokes as well as heart attacks.

20 Aug 2011

NIH-supported project expands genetic research into clinical setting

Northwestern University Feinberg School of Medicine researchers have received a $762,000 grant from the National Institutes of Health (NIH) to tailor drug treatments to patients' genomic information.

20 Aug 2011

High levels of calcium in coronary arteries increase risk of stroke, heart attack

The presence of calcium in coronary arteries is a much better predictor of heart attack and stroke than C-reactive protein among people with normal levels of LDL cholesterol, according to a study of more than 2,000 people led by a Johns Hopkins heart specialist.

19 Aug 2011

Mount Sinai to begin largest study of personalized medicine in clinical care setting

Mount Sinai School of Medicine has been awarded a $3.4 million grant over four years from the National Human Genome Research Institute (NHGRI) of the National Institutes of Health (NIH) to begin the largest study of its kind, in which a patient's genomic risk for disease is revealed in a lab, and then entered into an electronic medical record for use in determining treatment in the clinical care setting.

19 Aug 2011

People with metabolic abnormalities more likely to develop kidney disease

Metabolic syndrome comprises a group of medical disorders that increase people's risk of diabetes, heart disease, stroke, and premature death when they occur together. A patient is diagnosed with the syndrome when he or she exhibits three or more of the following characteristics: high blood pressure, high blood sugar, excess body fat in the waist/abdomen, low good cholesterol, and higher levels of fatty acids.

19 Aug 2011

FDA grants Fast Track designation for DARA's KRN5500 neuropathic pain relief drug

DARA BioSciences, Inc. announced today that its investigational drug KRN5500 has been granted Fast Track designation by the U.S. Food and Drug Administration (FDA) for the treatment of chemotherapy-induced neuropathic pain in patients with cancer.

19 Aug 2011

Bill Clinton on being ‘vegan’

Former President Bill Clinton has revealed that his diet is turning plant-based and heart-healthy. He said he believes the vegan regimen is helping to reverse the damage to his heart and blood vessels caused by cardiovascular disease.

18 Aug 2011

National analysis identifies Columbus as one of the Hypertension Hot Spots in the U.S.

A national analysis conducted by Sperling's BestPlaces and sponsored by Takeda Pharmaceuticals North America, Inc., identified Columbus, Ohio, as one of the nation's Hypertension Hot Spots, or cities that have hypertension risk factors and complications.

18 Aug 2011

Mayo researchers to translate genomic discoveries into tools for individualized medicine

Mayo Clinic researchers will receive more than $3 million in a four-year grant from the National Human Genome Research Institute to translate recent genomic discoveries into tools for individualized medicine. Recent advances in the genetics of heart and blood vessel diseases will be integrated into electronic medical records so doctors can more accurately determine patients' risk of heart attacks, blood vessel diseases and adverse reactions to heart medications.

18 Aug 2011

Patients with diabetes, hypertension more likely to develop open-angle glaucoma

Many Americans suffer from diabetes and hypertension and, according to a study by researchers at the University of Michigan Kellogg Eye Center, these individuals may have an increased risk of developing open-angle glaucoma.

18 Aug 2011

Ultrasound can predict high risk of stroke in patients with asymptomatic carotid stenosis

A new study shows that a simple ultrasound test may help to identify people at high risk of stroke who have a condition called asymptomatic carotid stenosis, a narrowing of the carotid artery found in the neck, in which few or no symptoms are present.

18 Aug 2011

Moderate social drinking reduces risk of dementia and cognitive impairment

Moderate social drinking significantly reduces the risk of dementia and cognitive impairment, according to an analysis of 143 studies by Loyola University Chicago Stritch School of Medicine researchers.

17 Aug 2011

Inflammation linked with RA increases patients risk of heart disease

Rheumatoid arthritis (RA) sufferers are at an increased risk of dying due to cardiovascular disease. A new five year study published in BioMed Central's open access journal Arthritis Research & Therapy showed that the risk of cardiovascular disease for people with RA is due to disease-related inflammation as well as the risk factors which affect the general population.

16 Aug 2011

AHRQ's new Spanish-language guide on heart medications

A free, illustrated easy-to-read pamphlet that compares drugs for preventing heart attacks, heart failure or strokes in people with stable coronary heart disease is one of six new Spanish-language publications from HHS' Agency for Healthcare Research and Quality that help patients compare treatments for common illnesses.

16 Aug 2011

Cholesterol News and Research

Further Reading

Researchers discover NPC1 protein as crucial for Ebola virus to enter host cells

Simvastatin may reduce spinal cord damage from ischemia/reperfusion injury

Disturbing images and threatening anti-smoking messages can 'boomerang'

CHL completes $18.4-million Series B financing round

ATGL produces key signaling molecules essential for regulation of lipid, energy metabolism

Calcium scores and heart disease risk, experts debate

Statin therapy may not be appropriate for certain patients at risk for stroke

NIH-supported project expands genetic research into clinical setting

High levels of calcium in coronary arteries increase risk of stroke, heart attack

Mount Sinai to begin largest study of personalized medicine in clinical care setting

People with metabolic abnormalities more likely to develop kidney disease

FDA grants Fast Track designation for DARA's KRN5500 neuropathic pain relief drug

Bill Clinton on being ‘vegan’

National analysis identifies Columbus as one of the Hypertension Hot Spots in the U.S.

Mayo researchers to translate genomic discoveries into tools for individualized medicine

Patients with diabetes, hypertension more likely to develop open-angle glaucoma

Ultrasound can predict high risk of stroke in patients with asymptomatic carotid stenosis

Moderate social drinking reduces risk of dementia and cognitive impairment

Inflammation linked with RA increases patients risk of heart disease

AHRQ's new Spanish-language guide on heart medications

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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