Research News and Research

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Researchers develop a novel, patient-derived model of ulcerative colitis

As reported in Nature Communications, researchers from Cleveland Clinic's Lerner Research Institute have developed a novel, patient-derived model of ulcerative colitis, which will help advance studies into new treatments for the chronic inflammatory bowel disease.

11 Jan 2021

Scientists receive $3.4 million to study care options for patients with chest pain due to anxiety

Indiana University School of Medicine and Regenstrief Institute research scientists have received a $3.4 million award from the Patient-Centered Outcomes Research Institute to investigate the best care options for the 40 percent of people who go to the hospital emergency department with chest pain that is determined to be caused by anxiety rather than a cardiac event.

11 Jan 2021

Study aims to halt further isolation of people aging with HIV during COVID-19 pandemic

The School of Medicine at the University of California, Riverside, has received a grant aimed at halting further isolation of people aging with HIV during the COVID-19 pandemic.

11 Jan 2021

Rice model could help clinicians personalize hip joints

Rice University engineers hope to make life better for those with replacement joints by modeling how artificial hips are likely to rub them the wrong way.

11 Jan 2021

Antibody recognition of linear SARS-CoV-2 epitopes preserved in mutated B.1.1.7 strain

In a recent medRxiv research paper, the US scientists examined the effects of non-synonymous mutations in the circulating B.1.1.7 strain of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on linear antibody epitope signal for viral spike glycoprotein and nucleoprotein – and demonstrated that mutations should not result in immune evasion.

11 Jan 2021

Family history of suicide attempt linked to lower neurocognitive functioning in youth

hildren and adolescents with a family history of suicide attempts have lower executive functioning, shorter attention spans, and poorer language reasoning than those without a family history, according to a new study by researchers from the Lifespan Brain Institute of Children's Hospital of Philadelphia and the University of Pennsylvania.

11 Jan 2021

Study monitors spatial shifts of liver gene expression in relationship to the circadian clock

Nothing in biology is static. Biological processes fluctuate over time, and if we are to put together an accurate picture of cells, tissues, organs etc., we have to take into account their temporal patterns. In fact, this effort has given rise to an entire field of study known as "chronobiology".

11 Jan 2021

Researchers demonstrate SARS-CoV-2 infection in human lung bronchioalveolar tissue model

Development of an in vitro human-derived tissue model for studying virus infection and disease progression in the alveolar cells of the lungs responsible for oxygen and carbon dioxide exchange with the blood might enable the study of possible therapies for acute respiratory distress syndrome (ARDS) triggered by SARS-CoV-2.

11 Jan 2021

Exercise during the first trimester of pregnancy helps avoid gestational diabetes

Pregnant women who exercise more during the first trimester of pregnancy may have a lower risk of developing gestational diabetes, according to a new study led by Samantha Ehrlich, an assistant professor in the Department of Public Health at the University of Tennessee, Knoxville, and adjunct investigator with the Kaiser Permanente Division of Research.

11 Jan 2021

Polymer patch provides controlled release of drugs for post-operative pain management

A Duke-led team of scientists has developed a bio-compatible surgical patch that releases non-opioid painkillers directly to the site of a wound for days and then dissolves away.

11 Jan 2021

MDC researchers develop a potent weapon against lymphomas

MDC researchers have developed a new approach to CAR T-cell therapy. The team has shown in Nature Communications that the procedure is very effective, especially when it comes to fighting follicular lymphomas and chronic lymphocytic leukemia, the most common type of blood cancer in adults.

11 Jan 2021

Study sheds new light on the role of MLL4 gene in Kabuki syndrome

Scientists have known for years that mutations in the MLL4 gene can cause Kabuki syndrome, a rare developmental disorder.

11 Jan 2021

Infectious disease early warning system compensates for existing gaps in surveillance

Researchers at Columbia University Mailman School of Public Health developed an infectious disease early warning system that includes areas lacking health clinics participating in infectious disease surveillance.

11 Jan 2021

Master Regulator proteins control cancer transcriptional identity

Thousands of different genetic mutations have been implicated in cancer, but a new analysis of almost 10,000 patients found that regardless of the cancer's origin, tumors could be stratified in only 112 subtypes and that, within each subtype, the Master Regulator proteins that control the cancer's transcriptional state were virtually identical, independent of the specific genetic mutations of each patient.

11 Jan 2021

Researchers identify bacterium that produces pharmaceutical all-purpose weapon

For some years, an active substance from the leaves of an ornamental plant has been regarded as a possible forerunner of a new group of potent drugs. So far, however, it has been very laborious to manufacture it in large quantities.

11 Jan 2021

Study uncovers strong links between a person's diet, gut microbes and health

Diets rich in certain plant-based foods are linked with the presence of gut microbes that are associated with a lower risk of developing conditions such as obesity, type 2 diabetes and cardiovascular disease, according to recent results from a large-scale international study that included researchers from King's College London, the Harvard T.H. Chan School of Public Health, Massachusetts General Hospital, the University of Trento, Italy, and health science start-up company ZOE.

11 Jan 2021

Freiburg researchers receive ERC funding to develop and test immunostimulatory drug candidates

With the Proof of Concept funding line, the ERC grants recipients of ERC frontier research funds (Starting, Consolidator, Advanced or Synergy grants) with 150.000 Euro to develop promising ideas with commercial or societal potential to the proof of concept stage.

11 Jan 2021

Research used to shape how dentistry can be carried out safely during Covid-19

Leading research at Newcastle University has been used to shape how dentistry can be carried out safely during the Covid-19 pandemic by mitigating the risks of dental aerosols.

11 Jan 2021

Simple monitoring system could reduce medication-related illness for people in care homes

New research from Swansea University suggests that a simple nurse- or carer-led medicines' monitoring system can help reduce medication-related illness for people living in residential care homes - and the process takes just a few minutes per patient.

11 Jan 2021

Trinity researchers discover key mechanism underlying bacterial skin colonization in atopic dermatitis

Researchers from Trinity College Dublin have discovered a key mechanism underlying bacterial skin colonization in atopic dermatitis, which affects millions around the globe.

11 Jan 2021

Research News and Research

Researchers develop a novel, patient-derived model of ulcerative colitis

Scientists receive $3.4 million to study care options for patients with chest pain due to anxiety

Study aims to halt further isolation of people aging with HIV during COVID-19 pandemic

Rice model could help clinicians personalize hip joints

Antibody recognition of linear SARS-CoV-2 epitopes preserved in mutated B.1.1.7 strain

Family history of suicide attempt linked to lower neurocognitive functioning in youth

Study monitors spatial shifts of liver gene expression in relationship to the circadian clock

Researchers demonstrate SARS-CoV-2 infection in human lung bronchioalveolar tissue model

Exercise during the first trimester of pregnancy helps avoid gestational diabetes

Polymer patch provides controlled release of drugs for post-operative pain management

MDC researchers develop a potent weapon against lymphomas

Study sheds new light on the role of MLL4 gene in Kabuki syndrome

Infectious disease early warning system compensates for existing gaps in surveillance

Master Regulator proteins control cancer transcriptional identity

Researchers identify bacterium that produces pharmaceutical all-purpose weapon

Study uncovers strong links between a person's diet, gut microbes and health

Freiburg researchers receive ERC funding to develop and test immunostimulatory drug candidates

Research used to shape how dentistry can be carried out safely during Covid-19

Simple monitoring system could reduce medication-related illness for people in care homes

Trinity researchers discover key mechanism underlying bacterial skin colonization in atopic dermatitis

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