Therapy News and Research

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Research could offer a new approach to treating malnourished, stunted kids

Millions of children in under-resourced parts of the world suffer from malnutrition and, consequently, stunted growth.

3 Jan 2024

Research team develops electrostatic materials for long-term bio-implants

Medical technology innovations achieved by integrating science and medicine have improved the quality of life for patients.

3 Jan 2024

How Artificial General Intelligence can transform radiation oncology

This paper provides an overview of how Artificial General Intelligence (AGI) can transform radiation oncology to elevate the standard of patient care, with the key insight being AGI's ability to exploit multimodal clinical data at scale.

3 Jan 2024

Study reveals high prevalence of chronic pain in TBI patients

Chronic pain affects approximately 60% of people living with traumatic brain injury (TBI), even up to 30 years after injury, according to new research published in The Journal of Head Trauma Rehabilitation (JHTR), the official journal of the Brain Injury Association of America.

3 Jan 2024

Rare immune cell holds key to predicting melanoma treatment success

A type of immune cell can help predict which patients may benefit most from cancer immunotherapies, researchers from King's College London, Guy's and St Thomas' Hospital Trust, and the Francis Crick Institute have found.

3 Jan 2024

Patients with HPV-related head and neck cancers treated in community centers less likely to survive

Care for patients with human papillomavirus (HPV)-related squamous cell cancers of the oropharynx (an area in back of the throat) is shifting toward community cancer centers, but patients treated in this setting may be less likely to survive, according to new research by investigators from the Johns Hopkins Kimmel Cancer Center and its Head and Neck Cancer Center.

3 Jan 2024

Mount Sinai study provides a mechanistic explanation for variations in individual responses to drugs

Mount Sinai researchers have shown for the first time that a person's beliefs related to drugs can influence their own brain activity and behavioral responses in a way comparable to the dose-dependent effects of pharmacology.

3 Jan 2024

Existing beta blocker investigated as novel sickle cell therapy

A beta blocker typically used to treat heart problems, hemangioma, migraines and anxiety could be a new therapeutic for patients with sickle cell disease. Researchers led by Ankit A. Desai, MD, associate professor of medicine at the Krannert Cardiovascular Research Center (KCVRC) at Indiana University School of Medicine, have been awarded a $3 million grant by the U.S. Department of Defense to evaluate the efficacy of this drug.

3 Jan 2024

Spicing up the fight: Saffron's powerful impact on prostate cancer revealed

Saffron-treated prostate cancer (PCa) cells.

3 Jan 2024

Living alone? Adopting a pet might help slow cognitive decline among older adults

Researchers investigated the association between pet ownership and cognitive decline in the elderly.

3 Jan 2024

Gut microbiota linked to social anxiety behaviors

Study reveals that gut microbiota from individuals with social anxiety disorder (SAD) can induce social fear behaviors in mice, suggesting a causal role of gut microbes in modulating behaviors relevant to SAD.

2 Jan 2024

Novel PET tracer accurately detects common cancer mutation for tailored treatment

A novel PET imaging tracer has been proven to safely and effectively detect a common cancer gene mutation that is an important molecular marker for tumor-targeted therapy.

2 Jan 2024

Study identifies α-MSH as therapeutic candidate for corneal endothelial disease

Findings from a pioneering study in The American Journal of Pathology, published by Elsevier, reveal that administration of the neuropeptide α-melanocyte-stimulating hormone (α-MSH) promotes corneal healing and restores normal eye function to an otherwise degenerating and diseased cornea by providing protection against cell death and promoting cell regeneration.

2 Jan 2024

New research highlights potential of cytisine for global smoking cessation efforts

A new study published in Addiction has found that cytisine, a low-cost, generic stop-smoking aid that has been used in eastern Europe since the 1960s, increases the chances of successful smoking cessation by more than two-fold compared with placebo and may be more effective than nicotine replacement therapy. It has a benign safety profile, with no evidence of serious safety concerns.

2 Jan 2024

Small molecule-switchable RNA platform enables control of therapeutic protein expression

Just like a doctor adjusts the dose of a medication to the patient's needs, the expression of therapeutic genes, those modified in a person to treat or cure a disease via gene therapy, also needs to be maintained within a therapeutic window.

2 Jan 2024

Microbial decoration enhances drug delivery specificity and safety

Announcing a new publication for Acta Materia Medica journal. Microorganisms are mostly distributed on the surface of our skin and intestines and have crucial roles in physiologic and metabolic processes, such as digestion and immunity, which are closely related to diseases.

29 Dec 2023

$15 million NCI grant awarded to investigate a type of radiation therapy for hard-to-treat cancers

The Radiopharmaceutical Therapy and Dosimetry Lab at Johns Hopkins Medicine, headed by George Sgouros, Ph.D., has been awarded a $15 million grant, to be dispersed over the next five years, from the National Cancer Institute at the National Institutes of Health.

28 Dec 2023

$Lisocabtagene maraleucel: A cost-effective second-line treatment for relapsed/refractory DLBCL$

Lisocabtagene maraleucel: A cost-effective second-line treatment for relapsed/refractory DLBCL

Lisocabtagene maraleucel (liso-cel), a CAR T-cell therapy, is a cost effective second line treatment for relapsed and refractory (hard to treat) diffuse large B-cell lymphoma (r/r DLBCL), according to a study published today in Blood Advances.

28 Dec 2023

Next-gen sequencing identifies thousands of cancer patients missing out on immunotherapy

Brigham researchers' findings from next-generation sequencing suggest that revising current cancer care guidelines could allow approximately 6,000 more patients in the U.S. to benefit from immunotherapy treatment each year

28 Dec 2023

New non-steroidal anti-inflammatory can inhibit the cytokine storm and preserve innate immunity

Very early in the COVID-19 pandemic clinical trials in patients hospitalized with COVID-19 confirmed that corticosteroids like dexamethasone reduced mortality, but they were harmful when applied at the first COVID-19 symptoms, due to the weakening of innate antiviral immunity, leading to delayed viral clearance and adverse outcomes in severe viral pneumonias.

28 Dec 2023

Therapy News and Research

Research could offer a new approach to treating malnourished, stunted kids

Research team develops electrostatic materials for long-term bio-implants

How Artificial General Intelligence can transform radiation oncology

Study reveals high prevalence of chronic pain in TBI patients

Rare immune cell holds key to predicting melanoma treatment success

Patients with HPV-related head and neck cancers treated in community centers less likely to survive

Mount Sinai study provides a mechanistic explanation for variations in individual responses to drugs

Existing beta blocker investigated as novel sickle cell therapy

Spicing up the fight: Saffron's powerful impact on prostate cancer revealed

Living alone? Adopting a pet might help slow cognitive decline among older adults

Gut microbiota linked to social anxiety behaviors

Novel PET tracer accurately detects common cancer mutation for tailored treatment

Study identifies α-MSH as therapeutic candidate for corneal endothelial disease

New research highlights potential of cytisine for global smoking cessation efforts

Small molecule-switchable RNA platform enables control of therapeutic protein expression

Microbial decoration enhances drug delivery specificity and safety

$15 million NCI grant awarded to investigate a type of radiation therapy for hard-to-treat cancers

Lisocabtagene maraleucel: A cost-effective second-line treatment for relapsed/refractory DLBCL

Next-gen sequencing identifies thousands of cancer patients missing out on immunotherapy

New non-steroidal anti-inflammatory can inhibit the cytokine storm and preserve innate immunity

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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