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New standard of care for treating advanced ovarian cancer

Results of a phase III, international randomized clinical trial demonstrate a new standard of care for treating advanced ovarian cancer that significantly reduces side-effects and post-operative deaths compared to the previously established treatment course.

3 Dec 2008

New guidelines for neuropathy

New guidelines developed by the American Academy of Neurology find a combination of blood tests and other specialized assessments appear to be the most helpful tests for finding the cause of neuropathy.

3 Dec 2008

Genetic breakdown in Fanconi anemia may have link to HPV-associated cancer

A genetic malfunction that causes DNA instability in people with the blood disorder Fanconi anemia may put them at high risk for squamous cell carcinomas linked to human papillomavirus (HPV), according to a study posted online ahead of print by Oncogene.

3 Dec 2008

Gene therapy used to alleviate sickle cell disease pathology

Using a harmless virus to insert a corrective gene into mouse blood cells, scientists at St. Jude Children's Research Hospital have alleviated sickle cell disease pathology.

3 Dec 2008

Researchers study newborns' umbilical cord blood to better understand fetal health risks from smoking mothers

Despite the well-known dangers of first- and secondhand smoke, an estimated ten percent of pregnant women in the U.S. are smokers.

3 Dec 2008

More alkaline diet strengthens skeletal health

Diets that are high in protein and cereal grains produce an excess of acid in the body which may increase calcium excretion and weaken bones, according to a new study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM).

3 Dec 2008

New evidence shows that the heart beats to its own drummer

They've uncovered some of the molecular circuitry within the cardiovascular system itself that controls the daily rise and fall of blood pressure and heart rate. The findings might also explain why commonly used diabetes drugs come with cardiovascular benefits, according to the researchers.

3 Dec 2008

New vaccine theory aimed at ticks and mosquitoes to prevent disease transmission

Most successful vaccines and drugs rely on protecting humans or animals by blocking certain bacteria from growing in their systems.

3 Dec 2008

Use of rapid response team in hospital not linked with reduction in cardio arrests or deaths

Although there is an effort to implement rapid response teams in hospitals throughout the country, new research suggests that they do not result in a reduced rate of cardiopulmonary arrests or deaths, according to a study in the December 3 issue of JAMA.

3 Dec 2008

Thrombosis patients face greater risks than previously believed

Deep venous thrombosis (DVT), the formation of blood clots in the lower limbs, is the third-most common vascular disease in North America after heart attack and stroke, and is a frequent complication in hospitalized patients.

3 Dec 2008

Prototype blood scanner detects even faint indicators of cancer

A team led by Stanford researchers has developed a prototype blood scanner that can find cancer markers in the bloodstream in early stages of the disease, potentially allowing for earlier treatment and dramatically improved chances of survival.

3 Dec 2008

Ship-in-a-bottle kit on a microchip

Sometimes physicists resort to tried and trusted model-making tricks. Scientists at the Max Planck Institute for Metals Research, the University of Stuttgart and the Colorado School of Mines have constructed micromachines using the same trick that model makers use to get ships into a bottle where the masts and rigging of the sailing ship are not erected until it is in the bottle.

3 Dec 2008

Risk of death may be higher with aprotinin commonly used during cardiac surgery

The risks of death are probably higher with aprotinin, a drug commonly used to control blood loss and transfusions during cardiac surgery, compared with lysine analogues, according to a study to be published in the January 20th issue of CMAJ.

3 Dec 2008

Reactions to HPV vaccine Gardasil rare

Research by Australian scientists has found that adverse reactions to the HPV vaccine Gardasil are rare and most schoolgirls are able to tolerate subsequent doses.

3 Dec 2008

Large study looks at genetic risks for schizophrenia and bipolar disorder

A multi-institution team of investigators led by researchers at the Keck School of Medicine of the University of Southern California (USC) has received $19 million in funding from the National Institutes of Mental Health (NIMH) for a groundbreaking effort to collect genetic information on tens of thousands of patients in order to study the genetic risks for schizophrenia and bipolar disorder.

3 Dec 2008

Portable eight-slice CT in ER increases chance of stroke survival and recovery

New research has found that the availability of a portable eight-slice computed tomography (CT) scanner in an emergency room can significantly increase the number of stroke victims who receive a potentially life-saving treatment.

3 Dec 2008

NicOx signs agreement with DSM for the commercial manufacture of naproxcinod drug substance

NicOx S.A. has announced it has signed an agreement with DSM for the commercial manufacture and supply of naproxcinod drug substance (or API, active pharmaceutical ingredient).

3 Dec 2008

Fruit flies provide better understanding of human heart disease

Researchers at the Burnham Institute for Medical Research have shown in both fruit flies and humans that genes involved in embryonic heart development are also integral to adult heart function.

3 Dec 2008

Patient safety compromised with faster drug approvals

With new drugs being reviewed by regulatory agencies and then released onto the market faster than ever before, patients' safety is being compromised, warns a study published on bmj.com.

3 Dec 2008

Yeast provides new insight into cholesterol-lowering drugs

Having discovered how a lowly, single-celled fungus regulates its version of cholesterol, Johns Hopkins researchers are gaining new insight about the target and action of cholesterol-lowering drugs taken daily by millions of people to stave off heart attacks and strokes.

3 Dec 2008