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Nanoparticle targets melanoma with siRNA

Research has shown that a particular receptor for the blood protein thrombin is overexpressed by highly metastatic melanoma cells.

20 Nov 2008

Low birth weight a risk factor for focal segmental glomerulosclerosis

Individuals who were underweight at birth are at increased risk of developing a condition called secondary focal segmental glomerulosclerosis, according to a study appearing in the January 2009 issue of the Clinical Journal of the American Society Nephrology ( CJASN ).

19 Nov 2008

New compounds break up cancer-causing protein STAT3 and destroy breast cancer tumors.

Two new compounds created by a University of Central Florida professor show early promise for destroying breast cancer tumors.

19 Nov 2008

Study identifies causes of bone loss in breast cancer survivors

Osteoporosis is a growing concern among breast cancer survivors and their doctors, because certain cancer drugs can cause bone loss.

19 Nov 2008

Pregnancy and fertility following bariatric surgery

Women who undergo weight-loss surgery, known as bariatric surgery, and later become pregnant after losing weight may be at lower risk for pregnancy-related diabetes and high blood pressure - complications that can seriously affect the mother or her baby - than pregnant women who are obese, according to new findings from the Agency for Healthcare Research and Quality that are published in the November 19 issue of JAMA.

19 Nov 2008

More data released on key diabetes genes

One of the most reliable indicators to predict that a person will develop type 2 diabetes is the presence of insulin resistance.

19 Nov 2008

Power3 Medical files two patent applications for breast cancer blood test

Power3 Medical Products, Inc. said today that two CIP patent applications have been filed for BC-SeraPro Breast Cancer blood test and biomarkers by Dr. Ira Goldknopf, its president and Chief Scientific Officer.

19 Nov 2008

Gentium S.p.A. updates on phase 3 trial of Defibrotide for severe veno-occlusive disease

Gentium S.p.A. announced today interim results from an independent Data Safety Monitoring Board (DSMB) review of the Company's Phase 3 treatment trial of Defibrotide for Severe Veno-Occlusive Disease (VOD).

19 Nov 2008

Genetic screening no better than traditional risk factors for predicting type 2 diabetes

Screening for a panel of gene variants associated with the risk for type 2 diabetes can identify adults at risk for the disorder but is not significantly better than assessment based on traditional risk factors such as weight, blood pressure and blood sugar levels.

19 Nov 2008

Enzyme discovery may lead to better heart and stroke treatments

A Queen's University study sheds new light on the way one of our cell enzymes, implicated in causing tissue damage after heart attacks and strokes, is normally kept under control.

19 Nov 2008

Celator Pharmaceuticals enrols first patient in phase 2 study of CPX-351 in acute myeloid leukemia

Celator Pharmaceuticals today announced that the first patient has been treated in a randomized Phase 2 clinical study of CPX-351 (Cytarabine:Daunorubicin) Liposome Injection in patients with newly diagnosed acute myeloid leukemia (AML).

19 Nov 2008

Garlic drug treats diabetes

A drug based on a chemical found in garlic can treat diabetes types I and II when taken as a tablet, a study in the new Royal Society of Chemistry journal Metallomics says.

19 Nov 2008

Systems biology brings hope of speeding up drug development

Almost every day brings news of an apparent breakthrough against cancer, infectious diseases, or metabolic conditions like diabetes, but these rarely translate into effective therapies or drugs, and even if they do clinical development usually takes well over a decade.

19 Nov 2008

Party drinking or drinking problem?

From sexual antics with co-workers to acts of violence and embarrassing text messages, alcohol fuels a number of "bad behaviors" at workplace and family holiday parties, according to a new study commissioned by Caron Treatment Centers, one of the nation's leading non-profit addiction treatment centers.

19 Nov 2008

Study to examine early, inherited form of Alzheimer's disease

The adult children of people diagnosed with inherited Alzheimer's disease are the focus of a new study to better understand the biology of the disease.

19 Nov 2008

Common ADHD drugs do not cause genetic damage in children

In contrast to recent findings, two of the most common medications used to treat attention deficit hyperactivity disorder (ADHD) do not appear to cause genetic damage in children who take them as prescribed, according to a new study by researchers at the National Institutes of Health (NIH) and Duke University Medical Center.

19 Nov 2008

Cancer drug bevacizumab linked to significantly increased risk of blood clots

An analysis of randomized controlled trials indicates that use of the cancer drug bevacizumab is associated with an increased risk of venous thromboembolism (blood clots in the deep veins of the legs or in the lungs), according to an article in the November 19 issue of JAMA, the Journal of the American Medical Association.

18 Nov 2008

Obese women who undergo bariatric surgery decrease pregnancy-related health complications

Obese women who have weight loss surgery before becoming pregnant have a lower risk of pregnancy-related health problems and their children are less likely to be born with complications, according to a new RAND Corporation study.

18 Nov 2008

Pros and cons of gastric bypass surgery

Severely obese patients who underwent two different gastric bypass techniques had lost up to 31 per cent of their Body Mass Index (BMI) after four years, with no deaths reported among the 50 study subjects, according to the November issue of the British Journal of Surgery.

18 Nov 2008

Trial of Gore-tex-type material to stop strokes

A study is under way at Rush University Medical Center using a small, soft-patch device made of a Gore-tex-type material - often used to make durable outerwear - to close a common hole found in the heart called a patent foramen ovale (PFO) in order to prevent recurrent strokes and transient ischemic attacks (TIAs) in adults.

18 Nov 2008