Cholesterol News and Research

RSS

Cholesterol is a waxy, fat-like substance made in the liver, and found in the blood and in all cells of the body. Cholesterol is important for good health and is needed for making cell walls, tissues, hormones, vitamin D, and bile acid.

Alnylam seeks CTA clearance to initiate ALN-PCS Phase I clinical trial for severe hypercholesterolemia

Alnylam Pharmaceuticals, Inc., a leading RNAi therapeutics company, announced today that it has filed a Clinical Trial Application (CTA) with the Medicines and Healthcare products Regulatory Agency (MHRA) to initiate a Phase I clinical trial with ALN-PCS, an RNAi therapeutic for the treatment of severe hypercholesterolemia.

11 Jul 2011

Global variation in relative burden of stroke and heart disease

An analysis of heart disease and stroke statistics collected in 192 countries by the World Health Organization (WHO) shows that the relative burden of the two diseases varies widely from country to country and is closely linked to national income, according to researchers at the University of California, San Francisco.

11 Jul 2011

Generics as a way to lower health care costs

As the nation seeks to expand health care coverage to more citizens without adding burdensome costs, researchers from Harvard University, Brigham and Women's Hospital and CVS Caremark reported that preventative health care may be significantly less costly than previously thought, due to expanded use of cost-effective generic medications for the treatment and prevention of chronic disease.

8 Jul 2011

Pediatricians debunk pearls of medical wisdom

Don't Cross Your Eyes-They'll Get Stuck that Way!, a new book by myth-fighting Indiana University School of Medicine pediatricians Aaron Carroll, M.D., M.S., and Rachel Vreeman, M.D., M.S., debunks the pearls of medical wisdom that many people and even their physicians believe are true. Be prepared to revise your thinking; no, an apple a day won't keep the doctor away and no, warm milk won't help you sleep.

8 Jul 2011

New strategy may combat age-associated infertility and birth defects

A strategy that has been shown to reduce age-related health problems in several animal studies may also combat a major cause of age-associated infertility and birth defects.

8 Jul 2011

Novartis Afinitor Phase III trial on tuberous sclerosis meets primary endpoint

Novartis Pharmaceuticals Corporation announced today Phase III trial results that showed more than one-third of patients taking Afinitor tablets experienced a 50% or greater reduction in the size of their subependymal giant cell astrocytomas, non-cancerous brain tumors associated with tuberous sclerosis complex.

8 Jul 2011

Cortisol hormone controls bile acid recycling process

Nature sees to it that we do not have "too much choler" in our body. A delicately equilibrated regulation system ensures that there is always exactly the right amount of bile in the gallbladder. When we are hungry, our body releases a hormone called cortisol, which is a glucocorticoid. Hepatic cells receive this hormone signal through their cortisol receptors and respond by filling the gallbladder with bile in preparation of the imminent food intake.

8 Jul 2011

Medicaid expands access to care, improves health for low-income adults

Researchers from Harvard School of Public Health (HSPH), Massachusetts Institute of Technology (MIT), the National Bureau of Economic Research (NBER), and Providence Health & Services have found that expanding low income adults' access to Medicaid substantially increases health care use, reduces financial strain on covered individuals, and improves their self-reported health and well-being.

7 Jul 2011

Egg yolks may protect against cardiovascular disease and cancer

One of nature's most perfect foods may be even better for us than previously thought. While eggs are well known to be an excellent source of proteins, lipids, vitamins and minerals, researchers at the University of Alberta recently discovered they also contain antioxidant properties, which helps in the prevention of cardiovascular disease and cancer.

7 Jul 2011

More evidence needed to determine how diets can reduce hypertension in individuals

New research by a University of Kent pharmacist should reveal more evidence about how diets can reduce blood pressure and other risk factors for heart disease in different individuals.

6 Jul 2011

Only half of obese Mexican-American adults receive diet, exercise advice from physicians

Only half of obese Mexican-American adults receive diet and exercise advice from their physicians, a new study finds, although obesity is on the rise for this group.

2 Jul 2011

AHRQ and Ad Council announce new campaign, 'Explore Your Treatment Options'

"Explore Your Treatment Options," a new multimedia ad campaign announced today by the U.S. Department of Health and Human Services' Agency for Healthcare Research and Quality and the Ad Council, encourages patients to become more informed about their options before choosing a treatment for a health condition or illness.

1 Jul 2011

Children and adolescents who eat candy less likely to be overweight or obese

Children and adolescents who eat candy tend to weigh less than their non-consuming counterparts, according to a new study published in Food & Nutrition Research, a peer-reviewed journal.

29 Jun 2011

Bayer Yakuhin seeks marketing authorization in Japan for EYLEA for treatment of wet AMD

Regeneron Pharmaceuticals, Inc. and Bayer HealthCare announced that Bayer Yakuhin, Ltd., Osaka, Japan, has submitted an application to the Ministry of Health, Labor and Welfare (MHLW) in Japan for marketing authorization for EYLEA, also known as VEGF Trap-Eye, for the treatment of the neovascular form of age-related macular degeneration (wet AMD).

29 Jun 2011

EAS, ESC develop new European guidelines to manage dyslipidaemias

Cardiovascular disease (CVD), driven by the global pandemics of obesity and diabetes, poses a daunting challenge to clinicians in the 21st century. Despite progress, there is still much to be done to improve the control of dyslipidaemia, a key risk factor.

28 Jun 2011

Lean gene and heart disease risk

According to a new study published Sunday, being lean may not always lead to a lower risk of heart disease and diabetes. The researchers have successfully identified a gene linked both to having a lean body and to a higher risk of metabolic diseases.

27 Jun 2011

Less body fat may increase risk of metabolic diseases

Having a lower percentage of body fat may not always lower your risk for heart disease and diabetes, according to a study by an international consortium of investigators, including two scientists from the Institute for Aging Research of Hebrew SeniorLife, an affiliate of Harvard Medical School (HMS).

27 Jun 2011

Diabetes more prevalent in every part of the world

A major international study collating and analyzing worldwide data on diabetes since 1980 has found that the number of adults with the disease reached 347 million in 2008, more than double the number in 1980. The research, published today in The Lancet, reveals that the prevalence of diabetes has risen or at best remained unchanged in virtually every part of the world over the last three decades.

27 Jun 2011

New data from Zafgen's ZGN-433 Phase 1b study on obesity presented at ADA 2011

Zafgen, Inc., a pharmaceutical company pioneering novel obesity therapeutics to help the body regain and sustain a lean, healthy state by targeting imbalances in fat metabolism, today announced new data from a Phase 1b study of ZGN-433, a selective methionine aminopeptidase 2 inhibitor (MetAP2), which showed a significant improvement in cardiovascular risk markers in severely obese subjects.

27 Jun 2011

Why breakfast with a friend could be just what the doctor ordered

Spending too much time alone and regularly skipping breakfast might be pushing you closer to heart disease, warns the National Heart Foundation of Australia.

26 Jun 2011