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Targeting opioid receptor offers relief for chronic itching

A common side effect of opioids is intense itching -- a problem for some patients who need the drugs for pain relief and for others fighting addiction.

17 Apr 2018

Scientists provide insight into how gene associated with autoimmunity contributes to disease

Researchers have provided new insight into how a gene associated with autoimmunity contributes to disease in humans.

17 Apr 2018

Study: Young children should be priority for snail fever treatment

Infants in some of the world's poorest regions are vulnerable to a common worm parasite infection and their treatment should become a priority, according to a study.

17 Apr 2018

Single FMT enema produces sustained and significant improvements in cognitive function

A single treatment using an optimized, targeted form of faecal microbiota transplantation (FMT) produces sustained clinical and cognitive improvements, according to the results of a long-term follow-up of patients with liver cirrhosis and hepatic encephalopathy (HE) who had participated in a short-term study.

16 Apr 2018

Study shows potential of web-based intervention to achieve weight loss in patients with NAFLD

Patients with non-alcoholic fatty liver disease who participated in a web-based lifestyle modification intervention achieved similar levels of weight loss and more rapid normalization of their liver enzymes than patients who participated in an intensive, group-based program.

13 Apr 2018

Study reports decreasing rates of liver transplantation among HCC patients in the U.S.

Patients with hepatocellular carcinoma (HCC) waiting for a liver transplant in the USA are now significantly less likely to receive a new liver than they were around a decade ago. A nationwide study presented today at The International Liver Congress™ 2018 in Paris, France, has confirmed that patients with HCC on the liver transplant list in the USA were more than 50% less likely to receive a transplant in 2014-2016 than they were in 2005-2007.

13 Apr 2018

OCA treatment stabilizes or reverses fibrosis/cirrhosis in patients with primary biliary cholangitis

The first results from the POISE biopsy sub-study have today confirmed that long-term treatment with obeticholic acid leads to the reversal or stabilization of fibrosis/cirrhosis in patients with primary biliary cholangitis who have had an incomplete response to ursodeoxycholic acid.

13 Apr 2018

Study confirms no survival benefit of adding SIRT to standard treatment for liver cancer

The final results of the palliative cohort of the SORAMIC study in patients with unresectable, locally advanced primary liver cancer have confirmed no clinical advantage to adding selective internal radiation therapy to standard sorafenib treatment compared with using sorafenib alone.

13 Apr 2018

Study: One-third of bacterial infections in patients with cirrhosis induced by MDR bacteria

A worldwide study initiated to investigate the epidemiology and outcomes of bacterial infections in hospitalized patients with liver cirrhosis has reported a prevalence of multi-drug-resistant bacteria of 34% and significant regional differences in the risk of developing a multi-drug-resistant infection.

13 Apr 2018

Researchers unlock new way to use cell's nanostructures as disease biomarkers

Researchers at the University of Sydney have established a method to identify individual nanoparticles released by human cells, opening the way for them to become diagnostic tools in the early-detection of cancers, dementia and kidney disease.

13 Apr 2018

Drink less to live longer - major new study

A new study has shown that the current safe limits of alcohol consumption are overestimated. In one of the largest worldwide alcohol consumption studies, the researchers noted that taking over six glasses of wine or six cans of beer per week can reduce years of life.

13 Apr 2018

HEV infections can be fatal and transmitted through blood products in immunosuppressed patients

Hepatitis E virus infection is once again in the spotlight, with two studies presented today at The International Liver Congress 2018 in Paris, France challenging the ideas that HEV infections are benign and self-limiting, and that blood-borne transmission is a rare event.

12 Apr 2018

New, sensitive HBV assay may allow earlier detection of hepatocellular carcinoma

Chronic hepatitis B virus (HBV) can progress to cirrhosis and hepatocellular carcinoma (HCC). A study published in The Journal of Molecular Diagnostics describes a new HBV assay that offers advantages over currently used methods because it has the capability to detect closed circular DNA (cccDNA) in serum, single cells, and preserved tissue samples.

12 Apr 2018

Study reveals unexpected mechanism that induces thirst after alcohol or sugar exposure

Why does drinking alcohol or consuming sugar make us thirsty? An international study of mice in Texas and humans in Europe reveals an unexpected anti-dehydration mechanism.

12 Apr 2018

Mediterranean-style diet linked to greater gut microbial diversity, lower risk of hospitalization

A diet that is Mediterranean style, and rich in vegetables and fermented milk products such as yoghurt, along with coffee, tea and chocolate, is associated with greater gut microbial diversity and a lower risk of hospitalization in patients with liver cirrhosis, according to the results of an international study presented today at The International Liver Congress™ 2018 in Paris, France.

12 Apr 2018

Breast cancers more likely to spread after surgery finds study

Breast cancer patients are more likely to experience a return and spread of their cancer within 18 months after a mastectomy or removal of the breast tumour along with healthy breast tissues. The reason for this or this association has been hitherto unexplained. According to a new study from MIT and the Whitehead Institute, the process of healing of the surgical scar after surgery is the cause for spread of the cancer.

12 Apr 2018

Experimental peptide drug shows promise against acute myeloid leukemia

In a study published online today in Science Translational Medicine, Albert Einstein College of Medicine researchers report that an experimental peptide drug shows promise against the often-lethal cancer acute myeloid leukemia and describe how the drug works at the molecular level.

11 Apr 2018

ALIVER produces animated short-film to raise public awareness about liver disease

An animated short-film produced by the ALIVER consortium titled "Life After Liver Failure", premieres tomorrow morning at the BioTech Village in The International Liver Congress 2018.

11 Apr 2018

Study offers new hope for patients with intrahepatic cholangiocarcinoma

Kandice Fogle, 43, had just moved to Houston when she began experiencing pain in her back and groin. After undergoing a CT scan, doctors found a large mass in her liver. A biopsy confirmed that she had intrahepatic cholangiocarcinoma, more commonly known as bile duct cancer.

11 Apr 2018

Is there such a thing as normal aging?

For 93-year-old Joseph Brown, the clearest sign of aging was his inability the other day to remember he had to have his pants unzipped to pull them on.

11 Apr 2018

Liver News and Research

Targeting opioid receptor offers relief for chronic itching

Scientists provide insight into how gene associated with autoimmunity contributes to disease

Study: Young children should be priority for snail fever treatment

Single FMT enema produces sustained and significant improvements in cognitive function

Study shows potential of web-based intervention to achieve weight loss in patients with NAFLD

Study reports decreasing rates of liver transplantation among HCC patients in the U.S.

OCA treatment stabilizes or reverses fibrosis/cirrhosis in patients with primary biliary cholangitis

Study confirms no survival benefit of adding SIRT to standard treatment for liver cancer

Study: One-third of bacterial infections in patients with cirrhosis induced by MDR bacteria

Researchers unlock new way to use cell's nanostructures as disease biomarkers

Drink less to live longer - major new study

HEV infections can be fatal and transmitted through blood products in immunosuppressed patients

New, sensitive HBV assay may allow earlier detection of hepatocellular carcinoma

Study reveals unexpected mechanism that induces thirst after alcohol or sugar exposure

Mediterranean-style diet linked to greater gut microbial diversity, lower risk of hospitalization

Breast cancers more likely to spread after surgery finds study

Experimental peptide drug shows promise against acute myeloid leukemia

ALIVER produces animated short-film to raise public awareness about liver disease

Study offers new hope for patients with intrahepatic cholangiocarcinoma

Is there such a thing as normal aging?

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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