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Evaluating the use of megadoses of corticosteroids as a treatment of COVID-19

In a new study, researchers have been investigating the effects of megadoses of corticosteroids on hospitalized COVID-19 patients.

26 Jan 2022

Cannabidiol inhibits SARS-CoV-2 replication in human cells and mice

In research recently published in the journal of Science Advances, an interdisciplinary team of researchers from the University of Chicago assessed the potential role of cannabidiol (CBD), a natural product extracted from the cannabis plant, to prevent and inhibit severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections in human cells and mice.

26 Jan 2022

Addiction medicine consults can reduce deaths in high-risk patients with substance use disorder

In-hospital addiction medicine consultations can reduce deaths in high-risk patients with substance use disorder, according to a new study published in the Journal of General Internal Medicine by University of Pittsburgh physicians.

25 Jan 2022

Oral polio vaccine could play a role against COVID-19

In a recent study posted to the medRxiv* preprint server, researchers performed an economic evaluation of the oral polio vaccine (OPV) to illustrate the potential non-specific (heterologous) effects (NSE) of live attenuated vaccines (LAVs).

25 Jan 2022

Spike-mediated CFTR inhibition accounts for airway inflammation in COVID-19

A new study looks at the molecular level inhibition of the protective CFTR gene by the SARS-CoV-2 spike protein.

25 Jan 2022

Impact of a third BNT162b2 dose on SARS-CoV-2 Omicron variant

In a new study, researchers assessed the extent and duration of the neutralization of SARS-CoV-2 Omicron variant of concern after the administration of two and three doses of the BNT162b2 mRNA vaccine.

25 Jan 2022

Study finds poorer outcomes after ICU discharge in patients with alcohol-associated cirrhosis

Patients with alcohol-associated cirrhosis have poorer outcomes after ICU discharge, compared to patients with cirrhosis linked to other causes, according to new Mayo Clinic research.

25 Jan 2022

Evaluation of cross-reactive T cell responses between SARS-CoV-2 and common-cold human coronaviruses

A new study investigated SARS-CoV-2 spike protein responses targeted by cross-reactive T cells that were isolated from convalescent COVID-19 individuals along with previously uninfected donors.

25 Jan 2022

Sensitivity and specificity of a “spit and mail” SARS-CoV-2 serology test

A recent study evaluated the sensitivity and specificity of a “spit and mail” serology test.

25 Jan 2022

In Portugal risk of hospitalization from Omicron is 75% lower than Delta

Researchers from Portugal reported a 75% risk reduction in hospitalizations for individuals infected with Omicron variant of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) compared to the Delta variant and a shorter length of stay and lower mortality if hospitalization does occur. Their paper is currently available on the medRxiv* preprint server while undergoing peer review.

24 Jan 2022

Lower risk of vaccine-breakthrough infections for mRNA-1273 recipients

Recently, a team of researchers examined breakthrough infections, hospitalizations, and mortality rates in double-dose messenger RNA (mRNA) vaccine recipients in a research letter published in the Journal of American Medical Association (JAMA).

24 Jan 2022

Attenuated tissue immune responses against SARS-CoV-2 in obese and non-obese patients

In a new study, researchers evaluated the single-cell transcriptomes from bronchiolar lavage in three adult cohorts comprising of obese and non-obese SARS-CoV-2 patients.

24 Jan 2022

Impact of SARS-CoV-2 booster vaccination on Delta variant resurgence in Israel

In a new study, researchers constructed a discrete-time age-of-infection age-stratified transmission model to accurately determine the individual to population-level data on SARS-CoV-2 Delta surge dynamics in Israel

24 Jan 2022

Exploring loss of Y chromosome in white blood cells as a risk-factor of life-threatening COVID-19 in men

Researchers published a study exploring the possibilities of predisposing men for a life-threatening disease course of COVID-19.

24 Jan 2022

Characterization of unique pathogenesis of SARS-CoV-2 Delta variant in mouse model

Researchers have investigated the pathology and inflammatory response to the Delta variant in mice.

24 Jan 2022

Study reveals perceived physical fatigability as an indicator of earlier mortality

How fatigued certain activities make an older person feel can predict the likelihood death is less than three years away, according to research published today in the Journal of Gerontology: Medical Sciences by University of Pittsburgh epidemiologists.

24 Jan 2022

Causal impact of spontaneous relaxation of social distancing practices on spread of SARS-CoV-2 in US

The purpose of a recent study was to examine the causal impact of a spontaneous relaxation of social distancing measures on the spread of SARS-CoV-2.

24 Jan 2022

Third dose of mRNA vaccine found to be effective in protecting against Omicron-related ED visits

A nationwide study from the Centers for Disease Control and Prevention (CDC) has found that mRNA booster shots (either Pfizer or Moderna) are 82 percent effective in protecting against COVID-19 Omicron variant-associated emergency department (ED) visits and 90 percent effective in protecting against COVID-19 Omicron variant-related hospitalizations.

24 Jan 2022

Investigators analyze diverse data to identify patterns of diagnostic pitfalls

When it comes to medical errors, diagnostic errors are the most common type of error reported by patients and the leading cause of malpractice claims. Brigham and Women's Hospital investigators complied and analyzed data from a diverse group of sources looking at data from 2004 to 2016 to identify patterns of diagnostic pitfalls.

24 Jan 2022

Screening of non-smoking women in Taiwan associated with lung cancer overdiagnosis

A new study based on data from a national cancer registry in Taiwan found evidence that lung cancer screening may be leading to overdiagnosis at the population level.

24 Jan 2022

Mortality News and Research

Evaluating the use of megadoses of corticosteroids as a treatment of COVID-19

Cannabidiol inhibits SARS-CoV-2 replication in human cells and mice

Addiction medicine consults can reduce deaths in high-risk patients with substance use disorder

Oral polio vaccine could play a role against COVID-19

Spike-mediated CFTR inhibition accounts for airway inflammation in COVID-19

Impact of a third BNT162b2 dose on SARS-CoV-2 Omicron variant

Study finds poorer outcomes after ICU discharge in patients with alcohol-associated cirrhosis

Evaluation of cross-reactive T cell responses between SARS-CoV-2 and common-cold human coronaviruses

Sensitivity and specificity of a “spit and mail” SARS-CoV-2 serology test

In Portugal risk of hospitalization from Omicron is 75% lower than Delta

Lower risk of vaccine-breakthrough infections for mRNA-1273 recipients

Attenuated tissue immune responses against SARS-CoV-2 in obese and non-obese patients

Impact of SARS-CoV-2 booster vaccination on Delta variant resurgence in Israel

Exploring loss of Y chromosome in white blood cells as a risk-factor of life-threatening COVID-19 in men

Characterization of unique pathogenesis of SARS-CoV-2 Delta variant in mouse model

Study reveals perceived physical fatigability as an indicator of earlier mortality

Causal impact of spontaneous relaxation of social distancing practices on spread of SARS-CoV-2 in US

Third dose of mRNA vaccine found to be effective in protecting against Omicron-related ED visits

Investigators analyze diverse data to identify patterns of diagnostic pitfalls

Screening of non-smoking women in Taiwan associated with lung cancer overdiagnosis

Industry Focus eBook - Forensics & toxicology (2nd edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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