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Proteins are complex molecules that are made up of amino acids. They can be found in every cell in the body, and carry out vital processes that keep human beings alive. Mutations in proteins can lead to a multitude of diseases, the most common being cancer.

UMass Amherst researcher aims to tackle bone damage in metastatic cancer

For some patients whose cancer has spread to their bones, the ensuing treatment can be more physically damaging than the original disease, leading to increased bone loss and fracture.

22 Jan 2024

Aerobic exercise could help combat non-alcoholic fatty liver disease

According to a study conducted on animal models and published in the journal Metabolism, aerobic exercise could help fight the non-alcoholic fatty liver disease, the most common liver disease worldwide: it affects nearly 24% of the global population and it usually causes a certain stigma among the affected people.

22 Jan 2024

Does space travel impact the human reproductive system?

How space travel, space radiation, and microgravity affect human reproductive functions.

22 Jan 2024

Discovery of toxic and protective short RNAs associated with Alzheimer's disease and superior memory capacity

Researchers explored how Death Induced by Survival gene Elimination through the analysis of RNA-induced silencing complex-bound short RNAs in Alzheimer's disease models influences neuronal survival and correlates with neurotoxicity in AD.

22 Jan 2024

Innovative COVID-19 test prototype uses bioluminescence for speedier results

Researchers used a luciferase-independent luminescence test to investigate whether the wild-type SARS-CoV-2 spike protein possesses pseudo-luciferase activity for Cypridina luciferin.

22 Jan 2024

Scientists discover a possible therapeutic target for pulmonary hypertension

A team led by Dr. Guadalupe Sabio at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) in Madrid has discovered a possible therapeutic target for pulmonary hypertension.

22 Jan 2024

Scientists discover key brain cells affected by COVID-19

A recent Cell Stem Cell study investigated whether SARS-CoV-2 infection leads to dopaminergic neuron senescence.

22 Jan 2024

How does social adversity influence biomarkers of stress and inflammation in children?

A recent study assessed whether social adversity affected the biomarkers of inflammation and stress in children.

22 Jan 2024

RecA protein skips "unwinding" step in DNA repair

Researchers from Tokyo Metropolitan University have been studying DNA repair by homologous recombination, where the RecA protein repairs breaks in double-stranded DNA by incorporating a dangling single-strand end into intact double strands, and repairing the break based on the undamaged sequence.

20 Jan 2024

Using AI to break the opioid addiction cycle

When Ben Brown, research assistant professor of chemistry, thinks about the opioid epidemic, he views the problem on a molecular level.

19 Jan 2024

Ludwig scientists deconstruct the blood supply of brain metastases

A Ludwig Cancer Research study has generated a granular portrait of how the cellular and molecular components of the blood vessels that feed brain metastases of melanoma and lung and breast cancers differ from those of healthy brain tissue, illuminating how they help shape the internal environment of tumors to support cancer growth and immune evasion.

19 Jan 2024

CRISPR off-switch discovered: Safer gene editing for future therapies

Using CRISPR, an immune system bacteria use to protect themselves from viruses, scientists have harnessed the power to edit genetic information within cells.

19 Jan 2024

Memory T cells learn and adapt: Post-Omicron immunity offers wider protection

It has been 4 years since the start of the COVID-19 pandemic. SARS-CoV-2 has yet to be eradicated and new variants are continuously emerging.

19 Jan 2024

Annexin-A1 targeted therapy beats several cancers

A new study published in Nature's cancer journal Oncogene highlights the effectiveness of MDX-124, the first therapeutic drug to target annexin-A1, a protein which is overexpressed in several cancer types and promotes tumour progression.

19 Jan 2024

AI scores breakthrough in anemia treatment with novel PHD inhibitor

Clinical stage generative artificial intelligence (AI)-driven biotechnology company InSilico Medicine ("InSilico"), today announced that the Journal of Medicinal Chemistry, an ACS Publications journal focusing on critical studies about molecular structure and biological activity, has published the company's discovery of a novel PHD inhibitor for the treatment of anemia.

19 Jan 2024