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Anosmia in pediatric COVID-19

The current paper, published in The Pediatric Infectious Disease Journal, examines the prevalence of anosmia in children with COVID-19 using a smell awareness survey.

24 May 2022

Hydration restores airway integrity in people with cystic fibrosis

Cystic fibrosis is a rare genetic disease which can cause very serious symptoms. In particular, patients suffer from chronic bacterial infections that can lead to respiratory failure.

24 May 2022

Study reports on the first instances of in-hospital, household transmission of monkeypox

A new retrospective study of seven patients diagnosed with monkeypox in the UK between 2018 and 2021, suggests that some antiviral medications might have the potential to shorten symptoms and reduce the amount of time a patient is contagious.

24 May 2022

Insilico Medicine nominates novel preclinical candidate targeting 3CL protease for COVID-19 treatment

Insilico Medicine, a clinical-stage end-to-end artificial intelligence (AI)-driven drug discovery company, today announced its nomination of a novel preclinical candidate (PCC) targeting 3C-like (3CL) protease for the treatment of COVID-19.

24 May 2022

Study expands understanding of the eye's immune response to viral infections

The cornea - the transparent protective outer layer of the eye critical to helping us see – produces a delicate and limited immune response to fight infections without damaging our vision, according to a ground-breaking new study from the Peter Doherty Institute for Infection and Immunity (Doherty Institute).

24 May 2022

Serological biomarker predicts severe Crohn's disease seven years prior to diagnosis

An international team led by a University of Toronto researcher has found that an antibody detectable in blood predicts severe Crohn's disease and is detectable up to seven years prior to disease diagnosis.

24 May 2022

UH experts in cloning and stem cell science take the first step toward unraveling cystic fibrosis

Two nationally recognized experts in cloning and stem cell science from the University of Houston are taking the first step toward limiting the consequences of chronic inflammation in cystic fibrosis (CF) by identifying the source of this persistent and enigmatic inflammation in CF lungs.

24 May 2022

Biologic medications used by IBD patients boost COVID-19 vaccine response

Getting the COVID-19 vaccination strengthened one type of immune response to the SARS-CoV-2 virus in inflammatory bowel disease (IBD) patients even though they were taking immunosuppressant medication, according to investigators at Cedars-Sinai.

23 May 2022

Using microfluidics and magnets to isolate rare, allergen-reactive white blood cells

Across the world, food allergies are on the rise. One of the most important cells in studying this ailment are basophils, which activate inflammation and other responses to allergens such as rashes, and sometimes, anaphylaxis.

23 May 2022

SARS-CoV-2 mRNA vaccines do not stimulate interferon stimulatory gene expression in Aicardi Goutières Syndrome patients

A new study aimed to evaluate the immunostimulatory potential of mRNA vaccines in AGS patients.

23 May 2022

Investigation of long-COVID in children with immunodeficiency

A new study focused on evaluating the prevalence of characteristic symptoms of Long COVID in immunodeficient and immunocompetent children.

23 May 2022

Repurposed drug clofoctol blocks SARS-CoV-2 replication in mouse study

A new paper presents the results of a mouse study using the repurposed antibacterial drug clofoctol against this virus.

23 May 2022

Pfizer COVID-19 vaccine-associated tinnitus responds to transcranial magnetic stimulation

Pfizer-BioNTech COVID-19 vaccine-associated tinnitus was relieved with a brief course of Transcranial Magnetic Stimulation treatment.

23 May 2022

Reduced exercise capacity is common in long COVID patients

In a recent study posted to the medRxiv* preprint server, researchers illustrated cardiac findings in coronavirus disease 2019 (COVID-19)-recovered individuals more than a year after infection.

22 May 2022

Olverembatinib a potent inhibitor of Omicron NTD-mediated cytokine release

Researchers determine whether mutations in the Omicron NTD influence its potential to stimulate myeloid cells and enhance inflammatory cytokine release.

22 May 2022

High air pollution may increase risk for life-threatening arrhythmias

Life-threatening arrhythmias are more common on days with highly polluted air, according to research presented today at Heart Failure 2022, a scientific congress of the European Society of Cardiology.

22 May 2022

Study reveals how ZBP1 could lead to a cytokine storm during COVID-19

Scientists from St. Jude Children's Research Hospital have shown that the innate immune sensor, ZBP1, and its associated inflammatory cell death pathway, PANoptosis, are major contributors to the negative effects of interferon treatment and high interferon levels in some COVID-19 patients.

20 May 2022

APOB-specific T cells may contribute to inflammation and further the progression of atherosclerosis

Preventing atherosclerosis, the underlying cause of heart disease, means scientists need to understand how immune cells drive inflammation in the arteries.

20 May 2022

The link between androgens and COVID-19

A new paper examines the association between androgens and COVID-19, as revealed by the research carried out on this topic throughout the pandemic.

20 May 2022

Study explores if prior infection with SARS-CoV-2 increased sensitivity to a mitochondrial toxin known to induce parkinsonism

The authors of the current study looked at the potential for an increased risk of parkinsonism following a bout of SARS-CoV-2 infection through accepted post-viral mechanisms.

20 May 2022

Inflammation News and Research

Anosmia in pediatric COVID-19

Hydration restores airway integrity in people with cystic fibrosis

Study reports on the first instances of in-hospital, household transmission of monkeypox

Insilico Medicine nominates novel preclinical candidate targeting 3CL protease for COVID-19 treatment

Study expands understanding of the eye's immune response to viral infections

Serological biomarker predicts severe Crohn's disease seven years prior to diagnosis

UH experts in cloning and stem cell science take the first step toward unraveling cystic fibrosis

Biologic medications used by IBD patients boost COVID-19 vaccine response

Using microfluidics and magnets to isolate rare, allergen-reactive white blood cells

SARS-CoV-2 mRNA vaccines do not stimulate interferon stimulatory gene expression in Aicardi Goutières Syndrome patients

Investigation of long-COVID in children with immunodeficiency

Repurposed drug clofoctol blocks SARS-CoV-2 replication in mouse study

Pfizer COVID-19 vaccine-associated tinnitus responds to transcranial magnetic stimulation

Reduced exercise capacity is common in long COVID patients

Olverembatinib a potent inhibitor of Omicron NTD-mediated cytokine release

High air pollution may increase risk for life-threatening arrhythmias

Study reveals how ZBP1 could lead to a cytokine storm during COVID-19

APOB-specific T cells may contribute to inflammation and further the progression of atherosclerosis

The link between androgens and COVID-19

Study explores if prior infection with SARS-CoV-2 increased sensitivity to a mitochondrial toxin known to induce parkinsonism

Industry Focus eBook - Forensics & toxicology (2nd edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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