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New drug target for herpes viruses

Scientists in the lab of Whitehead Institute Member Hidde Ploegh and the Harvard University lab of Rachelle Gaudet have solved the complex structure of a recently discovered protein that is found in a wide range of herpes viruses. This protein may prove to be a potential drug target.

11 Mar 2007

New drug target for herpes viruses

11 Mar 2007

Scientists test 'secret weapon' against tumours

Cancer Research UK scientists in Glasgow have devised a new method of attacking cancer cells. They report the findings in the Journal of Clinical Investigation.

11 Mar 2007

Islet cell trasnplant without immunosuppressive drugs successful in mice

Scientists at Weill Cornell Medical College may have reached a breakthrough in the search for a lasting cure for type 1 diabetes.

11 Mar 2007

Researchers show how endocrine cell types are produced in the pancreas

An international research team has identified the process by which pancreatic progenitor cells give rise to different endocrine cell types.

8 Mar 2007

Cannibalistic signals help mammalian embryos develop normally

A cannibalistic process called autophagy spurs dying embryonic stem cells to send "eat me" and "come get me" signals to have their corpses purged, a last gasp that paves the way for normal mammalian development, UT Southwestern Medical Center researchers have found.

8 Mar 2007

New discovery suggests novel methods for treating acute lymphoblastic leukemia

Investigators at St. Jude Children's Research Hospital have discovered previously unsuspected mutations that contribute to the formation of pediatric acute lymphoblastic leukemia (ALL), the most common cancer in children.

8 Mar 2007

Archemix granted two European patents

Archemix has announced today the issuance of two key, broad patents by the European Patent Office ("EPO"). The patents, EP 0 786 469 and EP 0 668 931, broadly cover methods for the identification and use of aptamers for therapeutic applications.

8 Mar 2007

Gene that prevents cancer also controls the skin's suntanning machinery

"The p53 tumor suppressor is commonly mutated in human cancer," explained David Fisher, director of the Melanoma Program in Medical Oncology at Dana-Farber Cancer Institute. "Now, we've found that it plays a role in the skin's tanning response."

8 Mar 2007

ARIUS Research granted two new U.S. patents for antibodies

ARIUS Research has announced that it has been granted two new United States patents for antibodies within their CD63 program. Patent 7,175,846. covers anti-cancer antibodies in ARIUS' partnered program for melanoma, breast and prostate cancers and protects the valuable site on the disease target that the drug candidate binds to.

8 Mar 2007

Researchers discover a new mechanism that regulates stem cell division

Errors in stem cell division can give rise to tumours. By studying stem cells in the fruit fly, scientists at the Institute for Research in Biomedicine (IRB Barcelona) have identified one of the mechanisms that govern how these cells divide.

7 Mar 2007

Discovery about fatty tissue that burns fat

In an article now being published in the leading American journal PNAS, a research team led by Barbara Cannon and Jan Nedergaard at the Wenner-Gren Institute, Stockholm University in Sweden, together with British and American scientists, have managed to show for the first time that the cells that become the so-called brown or white fat tissue already know from the very beginning what sort of fat tissue they will be.

7 Mar 2007

Children under stress develop more fevers

Children whose parents and families are under ongoing stress have more fevers with illness than other children. Published this month in the Archives of Pediatric and Adolescent Medicine, the study also shows the unanticipated conclusion that children's natural killer cell function, part of the body's innate immune system, increases under chronic stress, unlike adults, whose function is decreased.

6 Mar 2007

Giuliani does not mention abortion rights at Conservative conference

Former New York City Mayor Rudolph Giuliani (R) and former Massachusetts Gov. Mitt Romney (R) on Friday at the Conservative Political Action Conference in Washington, D.C., "position[ed] themselves as allies" to conservatives despite their "mixed" records on issues such as abortion rights and stem cell research, the Los Angeles Times reports.

5 Mar 2007

Mayo Clinic tests engineered measles virus against multiple myeloma

Mayo Clinic Cancer Center has opened a new Phase I clinical trial testing an engineered measles virus against multiple myeloma, a cancer of the bone marrow that currently has no cure. This is the third of a series of molecular medicine studies in patients testing the potential of measles to kill cancer.

5 Mar 2007