Cholesterol News and Research

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Cholesterol is a waxy, fat-like substance made in the liver, and found in the blood and in all cells of the body. Cholesterol is important for good health and is needed for making cell walls, tissues, hormones, vitamin D, and bile acid.

Larger trial study needed to decide fate of niacin

Niaspan is a cholesterol drug manufactured by Abbott Laboratories. Doctors have customarily prescribed Niacin to raise levels of HDL ("good" cholesterol) in patients taking a statin pill that is successfully lowering their LDL ("bad" cholesterol).

10 Jun 2011

Adaptation of fat cell membranes to obesity may play a key role in early stages of inflammatory disorders

The mechanisms by which obesity leads towards metabolic co-morbidities, such as diabetes mellitus, are poorly understood and of great public health interest. A study led by Matej Orešič from VTT Technical Research Centre of Finland suggests that adaptation of fat cell membranes to obesity may play a key role in the early stages of inflammatory disorders.

10 Jun 2011

IBC now qualified as 'patient-centered medical homes'

Independence Blue Cross (IBC) has reached a significant milestone with 100 primary care practices with more than 1,000 physicians now qualified as "patient-centered medical homes," and announced today that it is stepping up its efforts to support this transformation of primary care.

10 Jun 2011

Exercise protects against silent stroke: Study

Strokes can cause brain damage by cutting off blood flow to the brain. But unlike major strokes, recognizable by symptoms such as weakness on one side of the body and trouble speaking, so-called silent strokes by definition go unnoticed. Symptoms can include subtle memory and mobility problems, as well as an increased risk for future strokes, according to the American Academy of Neurology. Silent strokes are also different from mini-strokes, which are noticeable but last only for minutes or hours.

9 Jun 2011

University of Mississippi grants ChromaDex global rights to pterostilbene

ChromaDex Corp. and the University of Mississippi today announced the university has granted the natural products company the exclusive worldwide patent rights to a potential new therapeutic use for pterostilbene (tero-STILL-bean) as an anxiolytic or anti-anxiety agent. ChromaDex' pTeroPure® is an ultra-pure formulation of pterostilbene, a compound found in blueberries and demonstrated to have multiple health benefits.

9 Jun 2011

Merck announces changes to high-dose simvastatin prescribing information in the U.S.

Merck, known as MSD outside the United States and Canada, today announced changes to the prescribing information in the United States for the highest dose of simvastatin, 80 mg, and the use of simvastatin with certain other medicines.

9 Jun 2011

National survey finds women more likely to see doctor on regular basis than men

A national survey found that women were three times more likely to see a doctor on a regular basis than men. Even though men on average die younger than women and have higher mortality rates for heart disease, cancer, stroke and AIDS, trying to get a man to a doctor can be harder than pulling teeth. So, why do men hate it so?.

9 Jun 2011

U.S. FDA announces safety label changes for cholesterol-lowering medication, simvastatin

The U.S. Food and Drug Administration today is announcing safety label changes for the cholesterol-lowering medication simvastatin because the highest approved dose--80 milligram (mg)--has been associated with an elevated risk of muscle injury or myopathy, particularly during the first 12 months of use.

9 Jun 2011

Older people who engage in moderate to intense exercise less likely to have silent strokes

Older people who regularly exercise at a moderate to intense level may be less likely to develop the small brain lesions, sometimes referred to as "silent strokes," that are the first sign of cerebrovascular disease, according to a new study published in the June 8, 2011, online issue of Neurology, the medical journal of the American Academy of Neurology.

9 Jun 2011

New research finds 74% drop in myocardial infarction over 20-year period

Better control of cholesterol levels and blood pressure and a decline in smoking have contributed to a 74% drop in the risk of heart attack among nearly 10,000 civil servants working in London over a 20-year period, according to new research.

9 Jun 2011

Yikes! 5,085 kilojoules and 80.5 grams of fat in one burger

After the naming of a Hungry Jack's burger as the unhealthiest in the nation, all state governments are planning to introduce legislation requiring fast food outlets to list the energy content on their menus.

9 Jun 2011

DASH diet comes out on top

DASH diet, often recommended to help adults lower their blood pressure has ranked over more popular options in a ranking of 20 diets by U.S. News & World Report. The DASH diet, the magazine concluded, was the best overall. Government approved DASH standing for Dietary Approaches to Stop Hypertension was chosen by the magazine’s panel of nutrition experts among other things, being nutritious, easy to follow and protecting against heart disease and perhaps diabetes.

8 Jun 2011

Study determines surfactant protein-D as 'a good predictor' of cardiovascular disease

A blood protein known as surfactant protein-D (SP-D), which is mainly synthesised in the lungs, has been described as "a good predictor" of cardiovascular disease following a large study in North America.

8 Jun 2011

Topline results from 4SC vidofludimus Phase IIb trial against rheumatoid arthritis

4SC AG, a discovery and development company of targeted small molecule drugs for autoimmune diseases and cancer, today announced topline results from its randomised, double-blind, placebo-controlled Phase IIb clinical trial COMPONENT in RA.

8 Jun 2011

Apple peel reduces muscle atrophy and promotes muscle growth in mice

For Popeye, spinach was the key to extra muscle. For the mice in a new University of Iowa study, it was apples, or more precisely a waxy substance called ursolic acid that's found in apple peel.

8 Jun 2011

Low phosphate intake can reduce heart disease

Lowering phosphate intake in humans can reduce heart disease, according to research by experts at the University of Sheffield.

8 Jun 2011

Novel technique promises to reduce damage after heart attack

Scientists at the University of Leicester are investigating a novel technique that promises to protect heart muscle from life-threatening damage following a heart attack - simply by squeezing an arm. Heart attacks are the major cause of premature death in England, with massive implications for survival and costs of long-term health care.

7 Jun 2011

Bayer HealthCare seeks EU marketing authorization of VEGF Trap-Eye for treatment of wet AMD

Regeneron Pharmaceuticals, Inc. and Bayer HealthCare announced that Bayer HealthCare has submitted an application for marketing authorization in Europe for VEGF Trap-Eye for the treatment of the neovascular form of age-related macular degeneration (wet AMD).

7 Jun 2011

Androgen deprivation therapy may increase risk of diabetes in men with prostate cancer

Men with prostate cancer are at higher risk of developing diabetes or diabetes risk factors if they receive androgen deprivation therapy (ADT) to block the production or action of male hormones that can fuel the growth of this cancer.

6 Jun 2011

Preclinical study: Combination therapy of SPX-106 and D-tagatose reduces triglycerides and cholesterol

Spherix Incorporated, an innovator in biotechnology for therapy in diabetes, metabolic syndrome and atherosclerosis, and providers of technical and regulatory consulting services to food, supplement, biotechnology and pharmaceutical companies, today announced that its drug candidate, SPX-106, achieved statistically significant reductions in triglycerides and cholesterol when administered in combination with D-tagatose for nine weeks to genetically engineered mice prone to dyslipidemia.

3 Jun 2011

Cholesterol News and Research

Further Reading

Larger trial study needed to decide fate of niacin

Adaptation of fat cell membranes to obesity may play a key role in early stages of inflammatory disorders

IBC now qualified as 'patient-centered medical homes'

Exercise protects against silent stroke: Study

University of Mississippi grants ChromaDex global rights to pterostilbene

Merck announces changes to high-dose simvastatin prescribing information in the U.S.

National survey finds women more likely to see doctor on regular basis than men

U.S. FDA announces safety label changes for cholesterol-lowering medication, simvastatin

Older people who engage in moderate to intense exercise less likely to have silent strokes

New research finds 74% drop in myocardial infarction over 20-year period

Yikes! 5,085 kilojoules and 80.5 grams of fat in one burger

DASH diet comes out on top

Study determines surfactant protein-D as 'a good predictor' of cardiovascular disease

Topline results from 4SC vidofludimus Phase IIb trial against rheumatoid arthritis

Apple peel reduces muscle atrophy and promotes muscle growth in mice

Low phosphate intake can reduce heart disease

Novel technique promises to reduce damage after heart attack

Bayer HealthCare seeks EU marketing authorization of VEGF Trap-Eye for treatment of wet AMD

Androgen deprivation therapy may increase risk of diabetes in men with prostate cancer

Preclinical study: Combination therapy of SPX-106 and D-tagatose reduces triglycerides and cholesterol

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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