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Microglial states and their impact on Alzheimer's disease

Researchers examined 152,459 microglial transcriptomes from 443 individuals, identifying 12 transcriptional states and their relationship to Alzheimer's disease.

3 Oct 2023

Novel deep learning model to assess Alzheimer's disease progression risk

Patterns in the Alzheimer's disease (AD) trajectory using Mendelian randomization (MR) and deep learning (DL).

3 Oct 2023

Identification of Alzheimer's disease-associated micro-RNA biomarkers through network-based analysis

Micro-ribonucleic acids (miRNAs) linked to cognition and Alzheimer's disease (AD).

3 Oct 2023

How does Christmas impact eating behaviors and obesity?

Changes in nutritional patterns and eating behavior during the winter holiday season and its association with obesity.

3 Oct 2023

A better method to predict polygenic inheritance across multiple ancestries

Researchers report the results obtained from the use of a new PRS calculator called CT-SLEB on a multi-national GWAS database.

2 Oct 2023

Evidence reveals ferroptosis's critical role in male reproductive health

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2 Oct 2023

New study reveals BA.2.86 subvariant's surprising dance with antibodies

Researchers examined the antigenicity of the emerging SARS-CoV-2 subvariant BA.2.86, finding that it is not resistant to neutralizing antibodies from previously infected or vaccinated individuals, although it does show increased binding affinity to the ACE-2 receptor. The study highlights the subvariant's sensitivity and resistance to different classes of monoclonal antibodies, offering insights for future treatment and vaccine development.

2 Oct 2023

Could plant-based phytonutrients be the secret weapon against obesity?

This comprehensive review in the journal Foods explores the therapeutic potential of phytonutrients in combating obesity. The paper delves into various plant-based compounds like polyphenols, alkaloids, and terpenoids, detailing their mechanisms of action in inhibiting fat accumulation, regulating metabolism, and even altering gut microbiota.

1 Oct 2023

Study shows consanguinity may raise risk of type 2 diabetes and other common diseases

A new study finds that consanguinity – unions between close relatives – may increase the risk of common diseases such as type 2 diabetes and post-traumatic stress disorder (PTSD).

30 Sep 2023

New CRISPR-based gene-editing tool could lead to better treatments for genetic disorders

A new CRISPR-based gene-editing tool has been developed which could lead to better treatments for patients with genetic disorders.

29 Sep 2023

Study shows how tumors "hijack" genetic program used by developing nerves

Cancer tumors "hijack" the genetic program used by developing nerves. This is shown in a study by researchers at Umeå University, Sweden.

29 Sep 2023

New toolbox solves 50-year-old blood group mystery

Currently, a lot is known about which genes are responsible for our individual blood groups, however not much is understood about how and why the levels of the blood group molecules differ between one person and another.

29 Sep 2023

Stair climbing linked to reduced risk of heart disease, study finds

Forget walking 10,000 steps a day. Taking at least 50 steps climbing stairs each day could significantly slash your risk of heart disease, according to a new study from Tulane University.

29 Sep 2023

Parkinson's disease-related neuronal death more likely to occur at night

Disturbances in sleep patterns and the internal biological clock are frequently associated with Parkinson's disease.

29 Sep 2023

New research uncovers autozygosity's impact on common disease risks

Researchers explored the associations between autozygosity, measured as the fraction of the genome in runs of homozygosity (FROH), and common diseases, focusing on populations with high consanguinity rates.

29 Sep 2023

New research reveals how social isolation impacts behavior and lifespan in social species

Researchers used Camponotus fellah (carpenter ants) as a model species to perform behavioral tracking and ribonucleic acid-sequencing (RNA-seq) to study the transcriptome-level differences between socially isolated workers versus workers in groups.

29 Sep 2023

The fight against cancer: a comprehensive assessment of preventable and treatable cases

Researchers presented the findings of a population-based study conducted across 185 countries to estimate premature deaths due to 36 different types of cancers in 2020, a leading cause of premature deaths worldwide.

29 Sep 2023

Sushi and other raw seafood can spread antibiotic-resistant bacteria, study warns

Bacteria in raw seafood can make you sick. Seafood can also spread bacteria that are resistant to antibiotics.

28 Sep 2023

Unlocking the code: BigRNA's deep learning model predicts RNA behavior

Researchers have developed BigRNA, a groundbreaking deep learning model capable of predicting RNA behavior, including tissue-specific expression and splicing, directly from genomic DNA sequences. The model excels in identifying pathogenic variants and could be a game-changer in the development of personalized RNA-based therapies for treating genetic diseases.

28 Sep 2023

Are edible coatings the answer to fresher, eco-friendlier fruit and veg packaging?

Review sheds light on edible coatings as a sustainable alternative to traditional packaging and preservatives in the food industry, particularly for perishable items like fruits and vegetables.

28 Sep 2023

Genetic News and Research

Microglial states and their impact on Alzheimer's disease

Novel deep learning model to assess Alzheimer's disease progression risk

Identification of Alzheimer's disease-associated micro-RNA biomarkers through network-based analysis

How does Christmas impact eating behaviors and obesity?

A better method to predict polygenic inheritance across multiple ancestries

Evidence reveals ferroptosis's critical role in male reproductive health

New study reveals BA.2.86 subvariant's surprising dance with antibodies

Could plant-based phytonutrients be the secret weapon against obesity?

Study shows consanguinity may raise risk of type 2 diabetes and other common diseases

New CRISPR-based gene-editing tool could lead to better treatments for genetic disorders

Study shows how tumors "hijack" genetic program used by developing nerves

New toolbox solves 50-year-old blood group mystery

Stair climbing linked to reduced risk of heart disease, study finds

Parkinson's disease-related neuronal death more likely to occur at night

New research uncovers autozygosity's impact on common disease risks

New research reveals how social isolation impacts behavior and lifespan in social species

The fight against cancer: a comprehensive assessment of preventable and treatable cases

Sushi and other raw seafood can spread antibiotic-resistant bacteria, study warns

Unlocking the code: BigRNA's deep learning model predicts RNA behavior

Are edible coatings the answer to fresher, eco-friendlier fruit and veg packaging?

eBook: Using iPSCs models for human disease research and drug discovery eBook

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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