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Viewpoints: 'Accepted wisdom' about cutting entitlements disputed; Profit motive doesn't lead to good health care

It has become accepted economic wisdom that the only way to get control over America's looming budget deficits is to "reform entitlements." The accepted wisdom is wrong. ... Medicare and Medicaid costs are projected to soar. But here again, look closely and you'll see neither is really the problem. The underlying problem is the soaring cost of health care overall, combined with the aging of the boomer generation.

9 Jan 2013

Lilly, Boehringer Ingelheim announce top-line results from empagliflozin Phase III trials on T2D

Boehringer Ingelheim and Eli Lilly and Company today announced top-line results for four completed Phase III clinical trials for empagliflozin, an investigational sodium glucose co-transporter-2 (SGLT2) inhibitor being studied for treatment of patients with Type 2 Diabetes (T2D).

9 Jan 2013

Esperion reports positive results from ETC-1002 Phase 2 clinical trial on type 2 diabetes

Esperion Therapeutics, the leading developer of small molecule therapies for the treatment of cardiometabolic disorders, today announced positive results of a recently completed Phase 2 clinical trial of ETC-1002 in patients with type 2 diabetes with LDL-C lowering of up to 43% compared to placebo.

8 Jan 2013

New study finds that adults with diabetes in Ontario get fewer government-funded eye exams

A new study has found that adults with diabetes in Ontario are getting significantly fewer government-funded eye exams than they were a decade ago, a key component of high-quality diabetes care essential to preventing diabetes-related eye complications.

8 Jan 2013

Diabetes drug metformin works in different way than previously understood: Researchers

A team, led by senior author Morris J. Birnbaum, MD, PhD, the Willard and Rhoda Ware Professor of Medicine, with the Institute for Diabetes, Obesity, and Metabolism, Perelman School of Medicine, University of Pennsylvania, found that the diabetes drug metformin works in a different way than previously understood.

7 Jan 2013

UCSB scientists publish groundbreaking study results of Type 2 diabetes

While legions of medical researchers have been looking to understand the genetic basis of disease and how mutations may affect human health, a group of biomedical researchers at UC Santa Barbara is studying the metabolism of cells and their surrounding tissue, to ferret out ways in which certain diseases begin.

7 Jan 2013

Rhythm commences RM-493 Phase 2 trial in obesity

Rhythm announced today the initiation of a Phase 2 clinical trial with RM-493, the company's novel melanocortin 4 receptor (MC4R) agonist, for the treatment of obesity.

7 Jan 2013

TRIP-Br2 plays a major role in energy metabolism and fat storage

As part of their ongoing research on the physiologic factors that contribute to the development of obesity, Joslin Diabetes Center scientists have identified a cell cycle transcriptional co-regulator - TRIP-Br2 - that plays a major role in energy metabolism and fat storage.

6 Jan 2013

BMI mortality link questioned

Patients classified as overweight according to body mass index have a lower risk for mortality than normal-weight patients, show the results of a systematic review.

4 Jan 2013

Toxin-induced insulin resistance combated in mice

French researchers have found that a protein-bound uremic toxin, p-cresyl sulfate, contributes to the development of insulin resistance in mice, providing a new potential therapeutic target for treating chronic kidney disease, they say.

4 Jan 2013

Top 4 reasons why many dieters do not lose weight

The battle of the bulge is on - any movement on the scale yet? "Losing weight is one of the top resolutions made every year, yet only 20 percent of people achieve successful weight-loss and maintenance," says Jessica Bartfield,MD, internal medicine who specializes in nutrition and weight management at the Loyola Center for Metabolic Surgery & Bariatric Care.

4 Jan 2013

Fructose linked to food-seeking behavior and food intake

In a study examining possible factors regarding the associations between fructose consumption and weight gain, brain magnetic resonance imaging of study participants indicated that ingestion of glucose but not fructose reduced cerebral blood flow and activity in brain regions that regulate appetite, and ingestion of glucose but not fructose produced increased ratings of satiety and fullness, according to a preliminary study published in the January 2 issue of JAMA.

2 Jan 2013

Diabetes interventions show promise in primary care

Two lifestyle-based diabetes interventions developed in a clinical trial could successfully promote weight loss in primary care, research shows.

28 Dec 2012

Cellular metabolism of immune cells protect against viral infections and tumours

New research demonstrates that the cellular metabolism of certain immune cells is closely linked to their function, which includes protecting against viral infections and the development of tumours.

25 Dec 2012

Insulin resistance risk in sleepyhead teens

Inadequate amounts of sleep could put teenagers at increased risk for elevated insulin resistance, say US researchers.

22 Dec 2012

New work on Akt's role in cancer stem cell biology

The protein kinase Akt is a key regulator of cell growth, proliferation, metabolism, survival, and death. New work on Akt's role in cancer stem cell biology from the lab of senior author Honglin Zhou, MD, PhD and Weihua Li, co-first author, both from the Center for Resuscitation Sciences, Department of Emergency Medicine, Perelman School of Medicine, University of Pennsylvania, and Xiaowei Xu, Department of Pathology and Laboratory Medicine, appears in Molecular Cell.

21 Dec 2012

Combination of diet and exercise may prevent breast cancer in obese, postmenopausal women

Obese, postmenopausal women are at greater risk for developing breast cancer and their cancers tend to be more aggressive than those in lean counterparts.

20 Dec 2012

Echo Therapeutics prices underwritten public offering of 3,200,000 shares of common stock

Echo Therapeutics, Inc., a company developing its needle-free Symphony tCGM System as a non-invasive, wireless, transdermal continuous glucose monitoring system, today announced the pricing of a previously announced underwritten public offering of 3,200,000 shares of its common stock, offered at a price to the public of $0.95 per share.

20 Dec 2012

Maternal vitamin D deficiency could cause low birth weight

Women deficient in vitamin D early in their pregnancies are more likely to deliver babies with lower birth weights, University of Pittsburgh Graduate School of Public Health research reveals.

20 Dec 2012

Bipolar subtypes show neurobiologic differences

Results from a Taiwanese study show that there are significant neurobiologic differences between patients with bipolar I and II disorder.

20 Dec 2012

Glucose News and Research

Viewpoints: 'Accepted wisdom' about cutting entitlements disputed; Profit motive doesn't lead to good health care

Lilly, Boehringer Ingelheim announce top-line results from empagliflozin Phase III trials on T2D

Esperion reports positive results from ETC-1002 Phase 2 clinical trial on type 2 diabetes

New study finds that adults with diabetes in Ontario get fewer government-funded eye exams

Diabetes drug metformin works in different way than previously understood: Researchers

UCSB scientists publish groundbreaking study results of Type 2 diabetes

Rhythm commences RM-493 Phase 2 trial in obesity

TRIP-Br2 plays a major role in energy metabolism and fat storage

BMI mortality link questioned

Toxin-induced insulin resistance combated in mice

Top 4 reasons why many dieters do not lose weight

Fructose linked to food-seeking behavior and food intake

Diabetes interventions show promise in primary care

Cellular metabolism of immune cells protect against viral infections and tumours

Insulin resistance risk in sleepyhead teens

New work on Akt's role in cancer stem cell biology

Combination of diet and exercise may prevent breast cancer in obese, postmenopausal women

Echo Therapeutics prices underwritten public offering of 3,200,000 shares of common stock

Maternal vitamin D deficiency could cause low birth weight

Bipolar subtypes show neurobiologic differences

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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