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Circular extrachromosomal DNA identified as a potential target for new medulloblastoma therapies

A study of newly created databases of medulloblastoma has found that patients with tumors containing circular extrachromosomal DNA - loops of DNA found outside of regular chromosomes - are twice as likely to relapse and three times as likely to die within five years of diagnosis.

14 Nov 2023

Novel cancer immunotherapy compound degrades an enzyme found in cancer cells and T cells

Researchers in Purdue University's College of Pharmacy are leveraging the dual roles played by an enzyme found in both cancer cells and T cells to create a novel cancer immunotherapy compound.

14 Nov 2023

Study uses cellulose sheets to map body's extracellular vesicles, unlocking disease insights

Study demonstrates the use of cellulose nanofiber sheets for spatial analysis of extracellular vesicles, revealing their geographical heterogeneity in the human body, which could advance the understanding and treatment of diseases.

14 Nov 2023

Bioengineered human heart muscle cells and micro-tissues take flight to space

Mount Sinai's Cardiovascular Research Institute is sending bioengineered human heart muscle cells and micro-tissues into space for the first time on NASA's 29th SpaceX commercial resupply services mission, which launched Thursday, November 9.

14 Nov 2023

New app aims to ease burden on caregivers of dementia patients

With the number of Americans living with dementia expected to more than double to 13.8 million by 2060, two Regenstrief Institute research scientists and Indiana University professors have created an app to ease the burden on caregivers.

14 Nov 2023

New EU project aims to promote healthy and eco-friendly Mediterranean lifestyle

Within the past few decades, dietary habits have shifted dramatically toward the consumption of ultra-processed foods and drinks (UPFDs).

14 Nov 2023

Traffic emissions disrupt gene expression in human olfactory cells

Exposure to ultrafine particles from traffic alters the expression of many genes in human olfactory mucosa cells, a new study shows.

14 Nov 2023

Early Detection and Gender Disparities in COPD

In this interview, Dr. MeiLan Han, a distinguished pulmonologist and Chief of the Division of Pulmonary and Critical Care at the University of Michigan, shares her profound insights into Chronic Obstructive Pulmonary Disease (COPD).

14 Nov 2023

Introducing Luminescence 96: A Groundbreaking Advancement in Luminescence-Based Assays

With a vision to reenvision the lab and a passion for simplifying laboratory workflows with highly intuitive and functional designs, Byonoy launches Luminescence 96, further expanding its range of high-quality plate readers.

From Byonoy 14 Nov 2023

Decoding screen time: A thorough review of its impacts on young minds

The impacts of electronic media exposure and screen use on youths.

14 Nov 2023

New wireless biosensor technology could revolutionize healthcare

A wireless biosensor, developed by a Malmö University researcher, enables a more patient-controlled system whereby infections can be detected much earlier through smart catheters, smart diapers or wound dressings.

14 Nov 2023

New study identifies 4,749 key gene clusters that influence progression of 32 cancer types

Researchers at the Mount Sinai Center for Transformative Disease Modeling have released a groundbreaking study identifying 4,749 key gene clusters, termed "prognostic modules," that significantly influence the progression of 32 different types of cancer.

13 Nov 2023

New gel delivery system overcomes challenges of intratumoral cancer immunotherapy

Intratumoral therapy – in which cancer drugs are injected directly into tumors – is a promising treatment option for solid cancers but has shown limited success in clinical trials due to an inability to precisely deliver the drug and because most immunotherapies quickly dissipate from the site of injection.

13 Nov 2023

Automated referrals to pharmacy services dramatically increase appropriate statin prescription rates

The odds of prescribing the appropriate dose of statins - a medicine used to lower "bad" cholesterol levels - increased sixfold when automated referrals were made to pharmacy services, instead of relying on traditional prescribing methods, according to researchers at the Perelman School of Medicine at the University of Pennsylvania.

13 Nov 2023

Brain-inspired computing system achieves high accuracy in handwritten digit recognition

An experimental computing system physically modeled after the biological brain "learned" to identify handwritten numbers with an overall accuracy of 93.4%. The key innovation in the experiment was a new training algorithm that gave the system continuous information about its success at the task in real time while it learned.

13 Nov 2023

Non-invasive device detects Alzheimer's and Parkinson's biomarkers with high accuracy

An international team of researchers has developed a handheld, non-invasive device that can detect biomarkers for Alzheimer's and Parkinson's Diseases.

13 Nov 2023

Discovery of two new enzymes offers easier ways to study and manufacture complex natural chemicals

Slumbering among thousands of bacterial strains in a collection of natural specimens at The Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology, several fragile vials held something unexpected, and possibly very useful.

13 Nov 2023

"Christchurch mutation" can block detrimental effects of Alzheimer’s risk factor

Researchers at Gladstone Institutes have discovered that a rare genetic variant known as the "Christchurch mutation" can block detrimental effects of apolipoprotein E4, the best-established risk factor for the most common form of Alzheimer's disease.

13 Nov 2023

KAIST researchers develop an IV needle that irreversibly softens upon insertion

Intravenous (IV) injection is a method commonly used in patient's treatment worldwide as it induces rapid effects and allows treatment through continuous administration of medication by directly injecting drugs into the blood vessel.

13 Nov 2023

CRISPR-based gene-editing therapy could offer hope for people with inherited high LDL cholesterol

A single infusion of a CRISPR-based gene-editing therapy significantly reduced low-density lipoprotein cholesterol (LDL, the "bad cholesterol") in people who carry one gene for the inherited condition that results in very high LDL cholesterol levels and a high risk of heart attack at an early age, according to late-breaking science presented today at the American Heart Association's Scientific Sessions 2023.

13 Nov 2023

Technology News and Research

Circular extrachromosomal DNA identified as a potential target for new medulloblastoma therapies

Novel cancer immunotherapy compound degrades an enzyme found in cancer cells and T cells

Study uses cellulose sheets to map body's extracellular vesicles, unlocking disease insights

Bioengineered human heart muscle cells and micro-tissues take flight to space

New app aims to ease burden on caregivers of dementia patients

New EU project aims to promote healthy and eco-friendly Mediterranean lifestyle

Traffic emissions disrupt gene expression in human olfactory cells

Early Detection and Gender Disparities in COPD

Introducing Luminescence 96: A Groundbreaking Advancement in Luminescence-Based Assays

Decoding screen time: A thorough review of its impacts on young minds

New wireless biosensor technology could revolutionize healthcare

New study identifies 4,749 key gene clusters that influence progression of 32 cancer types

New gel delivery system overcomes challenges of intratumoral cancer immunotherapy

Automated referrals to pharmacy services dramatically increase appropriate statin prescription rates

Brain-inspired computing system achieves high accuracy in handwritten digit recognition

Non-invasive device detects Alzheimer's and Parkinson's biomarkers with high accuracy

Discovery of two new enzymes offers easier ways to study and manufacture complex natural chemicals

"Christchurch mutation" can block detrimental effects of Alzheimer’s risk factor

KAIST researchers develop an IV needle that irreversibly softens upon insertion

CRISPR-based gene-editing therapy could offer hope for people with inherited high LDL cholesterol

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