Endoplasmic reticulum (ER) News and Research

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CPF and PFF to partner with ATS to fund pulmonary fibrosis research

The Coalition for Pulmonary Fibrosis, the Pulmonary Fibrosis Foundation, and the American Thoracic Society-the world's leading professional organization for pulmonary, critical care and sleep medicine-today announced that the CPF and the PFF will again partner with the ATS to fund pulmonary fibrosis research.

21 Mar 2013

BUSM awarded funding to provide opioid prescribing education to health care providers

Awarded the first of its kind funding to provide FDA-mandated opioid prescribing education, Boston University School of Medicine has launched a program to train health care providers how to safely and effectively manage patients with chronic pain using opioid analgesics.

19 Mar 2013

More med school seniors seek primary care residency

The increased interest in residencies for internal medicine, family medicine or pediatrics may, in part, be the result of increased competition for specialty slots.

19 Mar 2013

Lack of very long chain fatty acids does not cause blindness in children with Stargardt type 3

Vision scientists long have thought that lack of very long chain fatty acids in photoreceptor cells caused blindness in children with Stargardt type 3 retinal degeneration, an incurable eye disease. But researchers at the University of Utah's John A. Moran Eye Center have shown in a new study that lack of these fatty acids does not cause blindness, meaning that the search for the mechanism that robs sight from children with the disease must start anew.

12 Mar 2013

Advancement in re-engineering photosynthesis can transform plants into bio-factories

Scientists are reporting an advance in re-engineering photosynthesis to transform plants into bio-factories that manufacture high-value ingredients for medicines, fabrics, fuels and other products. They report on the research in the journal ACS Synthetic Biology.

8 Mar 2013

Study finds emergency departments provide not enough information about child passenger safety

Each year, more than 130,000 children younger than 13 are treated in U.S. emergency departments after motor-vehicle crash-related injuries.

6 Mar 2013

Researchers use familial and sporadic patient-derived iPSCs to model Alzheimer's disease

Working with a group from Nagasaki University, a research group at the Center for iPS Cell Research and Application (CiRA) at Japan's Kyoto University has announced in the Feb. 21 online publication of Cell Stem Cell has successfully modeled Alzheimer's disease (AD) using both familial and sporadic patient-derived induced pluripotent stem cells (iPSCs), and revealed stress phenotypes and differential drug responsiveness associated with intracellular amyloid beta oligomers in AD neurons and astrocytes.

21 Feb 2013

Weekend reading: Why a trip to the ER costs more than a college semester; Searching for the 'stomach share;' Lessons for the U.S. from Rwanda

Routine Care, Unforgettable Bills .... Sean was allowed to see the doctor only after he advanced MD Anderson $7,500 from his credit card. ... The total cost, in advance, for Sean to get his treatment plan and initial doses of chemotherapy was $83,900.

21 Feb 2013

Better risk models needed for estrogen receptor-negative breast cancer

A breast cancer risk prediction model developed for African Americans tends to underestimate risk in certain subgroups, according to a new study from the Slone Epidemiology Center (SEC) at Boston University.

16 Feb 2013

Many pregnant women with sexually transmitted infections do not get needed treatment

Many pregnant women with sexually transmitted infections aren't getting the treatment they need when they visit emergency rooms, according to a new Michigan State University study that highlights a wholly preventable risk to unborn children and raises questions about current medical guidelines.

10 Feb 2013

Covidien first quarter sales increase 5% to $3.06 billion

Covidien plc today reported results for the first quarter of fiscal 2013 (October - December 2012). First-quarter net sales of $3.06 billion were 5% above the $2.90 billion reported in the comparable period a year ago. Foreign exchange rate movement lowered the quarterly sales growth rate by one percentage point.

25 Jan 2013

Studies in JAMA examine hospital readmissions and effects of new Medicare penalties

Research shows that poor coordination among providers can lead to patients returning to the hospital. In addition, the new payment procedures are likely to affect academic medical centers and safety net hospitals.

24 Jan 2013

Actavis seeks FDA approval to market generic Opana ER

Watson Pharmaceuticals, Inc. today confirmed that Actavis South Atlantic LLC, which was acquired by Watson in October, has filed an Abbreviated New Drug Application (ANDA) with the U.S. Food and Drug Administration (FDA) seeking approval to market Oxymorphone Hydrochloride Extended-release Tablets.

23 Jan 2013

Possible connection between mitochondrial CYP2D6 and Parkinson's

With a new insight into a model of Parkinson's disease, researchers from the University of Pennsylvania School of Veterinary Medicine have identified a novel target for mitigating some of the disease's toll on the brain.

19 Jan 2013

Tamoxifen can counteract some pathologic features in mouse model of DMD

A new study has found that tamoxifen, a well-known breast cancer drug, can counteract some pathologic features in a mouse model of Duchenne muscular dystrophy (DMD). At present, no treatment is known to produce long-term improvement of the symptoms in boys with DMD, a debilitating muscular disorder that is characterized by progressive muscle wasting, respiratory and cardiac impairments, paralysis, and premature death.

16 Jan 2013

Aggressive breast cancer’s metastasis molecular switch identified

Scientists at Weill Cornell Medical College have discovered the molecular switch that allows aggressive triple negative breast cancer cells to grow the amoeba-like protrusions they need to crawl away from a primary tumor and metastasize throughout the body. Their findings, published in Cancer Cell, suggest a novel approach for developing agents to treat cancer once it has spread.

15 Jan 2013

Viewpoints: Republicans reject their own market-based ideas; Analyzing entitlement spending; Access to after-hours care reduces ER visits

It's harder and harder for politicians on the right to think straight about health care. Conservatives once genuinely interested in finding market-based ways for the government to expand health insurance coverage have, since the rise of Obamacare, made choices that are dysfunctional, even from their own perspective. Start with the decision of the vast majority of Republican governors to refuse to set up the state insurance exchanges required under the law.

2 Jan 2013

Dedicated palliative care consults improve outcomes

Data from a long-term care facility in the USA indicate that a dedicated palliative care consult service results in a more favorable course of treatment and clinical outcomes for residents.

19 Dec 2012

Conn. shootings spur questions about adequacy of mental health services

Lawmakers in both chambers are calling for Congress to start a conversation about mental health issues in the wake of last week's deadly shooting at a Connecticut elementary school, with one goal of ensuring adequate funding for services for those who need treatment.

19 Dec 2012

Tumor cells manipulate unfolded protein response

Researchers at the University of California, San Diego School of Medicine report that tumor cells use stress signals to subvert responding immune cells, exploiting them to actually boost conditions beneficial to cancer growth.

19 Dec 2012

Endoplasmic reticulum (ER) News and Research

CPF and PFF to partner with ATS to fund pulmonary fibrosis research

BUSM awarded funding to provide opioid prescribing education to health care providers

More med school seniors seek primary care residency

Lack of very long chain fatty acids does not cause blindness in children with Stargardt type 3

Advancement in re-engineering photosynthesis can transform plants into bio-factories

Study finds emergency departments provide not enough information about child passenger safety

Researchers use familial and sporadic patient-derived iPSCs to model Alzheimer's disease

Weekend reading: Why a trip to the ER costs more than a college semester; Searching for the 'stomach share;' Lessons for the U.S. from Rwanda

Better risk models needed for estrogen receptor-negative breast cancer

Many pregnant women with sexually transmitted infections do not get needed treatment

Covidien first quarter sales increase 5% to $3.06 billion

Studies in JAMA examine hospital readmissions and effects of new Medicare penalties

Actavis seeks FDA approval to market generic Opana ER

Possible connection between mitochondrial CYP2D6 and Parkinson's

Tamoxifen can counteract some pathologic features in mouse model of DMD

Aggressive breast cancer’s metastasis molecular switch identified

Viewpoints: Republicans reject their own market-based ideas; Analyzing entitlement spending; Access to after-hours care reduces ER visits

Dedicated palliative care consults improve outcomes

Conn. shootings spur questions about adequacy of mental health services

Tumor cells manipulate unfolded protein response

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