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Adjustable Tip Spacing Pipette Improves Productivity & Reproducibility

INTEGRA reports on a new technical note produced by Analytik Jena (www.analytik-jena.de/en.html) that compares the performance of the INTEGRA VOYAGER adjustable tip spacing multichannel pipette with a manual single channel pipette for performing real-time PCR experiments.

From INTEGRA Biosciences 17 Nov 2015

Corning signs agreement to become global distributor for popular BioCision products

Corning Incorporated and BioCision, LLC today announced an agreement that will enable laboratories around the world to further standardize and simplify key steps in their cell culture workflow.

17 Nov 2015

New study provides possible way to overcome stem cell research’s developmental arrest problem

Johns Hopkins researchers report that a new study of mouse cells has revealed reasons why attempts to grow stem cells to maturity in the laboratory often fail, and provided a possible way to overcome such "developmental arrest."

13 Nov 2015

Some gut microbes may hold the key to regulating good health, say Oregon scientists

University of Oregon scientists have found that strength in numbers doesn't hold true for microbes in the intestines. A minority population of the right type might hold the key to regulating good health.

12 Nov 2015

Research opens door for developing biomarker tests to detect cancers early

Biomarkers, which allow diseases to be diagnosed and staged based on relatively non-invasive blood tests, have been identified for several types of cancers, but for most cancers remain elusive. Now, research conducted at the RIKEN Center for Life Science Technologies in Japan and the Harry Perkins Institute of Medical Research in Australia has identified a large number of genes that are upregulated in many different types of cancer, opening the door for developing biomarker tests that could be used to detect cancers early, allowing for prompt treatment.

10 Nov 2015

NTU Singapore scientists harness dead bacteria to destroy colon tumours cells effectively

Scientists from Nanyang Technological University have successfully used dead bacteria to kill colorectal cancer cells. Harvesting the Clostridium sporogenes bacteria found commonly in soil, the NTU team was able to harness the bacteria in its dead form, and its secretions, to destroy colon tumours cells effectively.

9 Nov 2015

Researchers identify mechanisms underlying postnatal organ maturation

Any expectant mother will tell you that she wants her baby's organs to develop properly in the womb. What she may not realize, however, is that a child's internal organs continue to develop for months and years after birth. This critical period is full of cellular changes that transform the organization and function of most tissues. But the exact mechanisms underlying postnatal organ maturation are still a mystery.

5 Nov 2015

Oxford professor wins Heinrich Wieland Prize for pioneering method that helps control nerve cells with light

Gero Miesenböck was the first to insert a light-controlled on/off switch into brain cells. His pioneering method allows scientists to switch nerve cells on and off selectively and observe how the behaviour of, for example, fruit flies or mice changes as a result. In this way, researchers can learn in a step-by-step process what behaviour the studied brain circuits control and what goes awry in disease. For his method, hailed as a "breakthrough of the decade," Professor Gero Miesenböck of the University of Oxford will receive the 100,000-euro Heinrich Wieland Prize of the Boehringer Ingelheim Foundation in Munich on November 6, 2015.

4 Nov 2015

Study provides novel insight into the evolution of hepatitis A virus and how it spreads to humans

Researchers at the University of North Carolina at Chapel Hill are part of an international team led by the University of Bonn, Germany, who have found a link between the origin of hepatitis A virus (HAV) and small mammals.

4 Nov 2015

VUMC, UCSF investigators awarded $6 million NIH grant to develop implantable artificial kidney

The National Institutes of Health has awarded a four-year, $6 million grant to investigators at Vanderbilt University Medical Center and the University of California at San Francisco to develop an implantable artificial kidney.

3 Nov 2015

President and CEO of Protein Sciences elected as 2015 Fellow of the International Society for Vaccines

Protein Sciences Corporation, the makers of Flublok Influenza Vaccine, announced today that Dr. Manon Cox, President and CEO, was elected as a 2015 Fellow of the International Society for Vaccines (ISV). The ISV is an esteemed organization dedicated to the development, advancement and use of vaccines to prevent and control disease.

30 Oct 2015

Scalable production of gene therapy vectors: an interview with Frank Ubags

Gene therapy involves introducing genetic material into cells to replace missing or malfunctioning genes or to add a gene to express a beneficial protein in order to treat certain diseases, such as cancer or inherited disorders.

26 Oct 2015

Amgen's IMLYGIC receives positive opinion from CHMP for treatment of melanoma

Amgen today announced that the Committee for Medicinal Products for Human Use, the scientific committee of the European Medicines Agency, has adopted a positive opinion recommending that IMLYGIC (talimogene laherparepvec) be granted approval for the treatment of adults with unresectable melanoma that is regionally or distantly metastatic (Stage IIIB, IIIC and IVM1a) with no bone, brain, lung or other visceral disease.

23 Oct 2015

Study shows how dietary fatty acids affect development and progression of multiple sclerosis

Dietary fatty acids affect the development and progression of autoimmune chronic-inflammatory diseases such as multiple sclerosis. In a collaborative study between the Departments of Neurology at the Ruhr-Universität Bochum (St. Josef-Hospital) and the Friedrich Alexander Universtiy Erlangen, researchers now found that long-chain fatty acids promote the development and propagation of CNS reactive immune cells in the intestinal wall. On the contrary, short-chain fatty acids promote the development and propagation of regulatory cells in the immune system.

22 Oct 2015

Discovery may lead to new anti-metastasis therapies for advanced-stage brain cancer patients

It's no surprise that people enjoy warm places like Hawaii but may suffer in hostile locales such as Antarctica. A tumor suppressor gene called PTEN is similar in that it is affected by the microenvironments of certain bodily organs to which it travels.

20 Oct 2015

Data shows romosozumab better than teriparatide in increasing bone strength in postmenopausal women

Amgen (NASDAQ: AMGN) and UCB (Euronext Brussels: UCB) today presented additional findings from an exploratory sub-study of the previously reported romosozumab Phase 2 trial.

13 Oct 2015

Antiviral agent protects rhesus monkeys from deadly Ebola virus

Rhesus monkeys were completely protected from the deadly Ebola virus when treated three days after infection with a compound that blocks the virus's ability to replicate. These encouraging preclinical results suggest the compound, known as GS-5734, should be further developed as a potential treatment, according to research findings to be presented tomorrow at the IDWeek conference.

12 Oct 2015

High levels of satiety hormone leptin contribute to cardiovascular disease in obese individuals

While high levels of the satiety hormone leptin don't help obese individuals lose weight, they do appear to directly contribute to their cardiovascular disease, researchers report.

8 Oct 2015

Scientists awarded £417,000 to develop a gel to advance breast cancer research, reduce animal testing

Scientists at the Universities of Manchester and Nottingham have been funded to develop a gel that will match many of the biological structures of human breast tissue, to advance cancer research and reduce animal testing.

7 Oct 2015

Researchers identify role of microglia during early stages of Alzheimer's disease

For the first time, researchers have determined how toxic tau fibrils spread by the help of brain immune cells called microglia during the early stages of Alzheimer's disease (AD). The discovery of this new pathway may lead to a therapeutic target for AD, one that has not been previously identified.

5 Oct 2015