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Fatty acids disrupt glutamate transporter function in brain cells

Glutamate transporters pump glutamate from the synaptic cleft back into brain cells after its release during neurotransmission.

12 Dec 2024

Study sheds light on how deep sleep supports memory formation

It has been known for nearly 20 years that slow, synchronous electrical waves in the brain during deep sleep support the formation of memories.

12 Dec 2024

Exosomes: A double-edged sword in hepatocellular carcinoma

The TIME is a dynamic network composed of cancer cells, immune cells, and stromal components. During the early stages of tumorigenesis, the TIME attempts to eliminate abnormal cells through immune surveillance.

11 Dec 2024

UVM scientists discover new mechanism for blood flow regulation in the brain

A team of UVM scientists led by Mark Nelson, Ph.D., from the Larner College of Medicine at the University of Vermont, has uncovered a novel mechanism that reshapes our understanding of how blood flow is regulated in the brain.

9 Dec 2024

Novel glucose-sensitive membrane offers improved insulin regulation for diabetic patients

For years, glucose-sensitive membranes have been a key focus for improving controlled insulin release in diabetes treatments.

9 Dec 2024

Researchers discover new receptor in pain signaling pathway

Researchers at the NYU Pain Research Center have found a new receptor for nerve growth factor that plays an important role in pain signaling, even though it does not signal on its own, according to a study published in the Journal of Clinical Investigation.

6 Dec 2024

Reimagining axons with the pearls-on-a-string model

In a provocative new study, scientists challenge a fundamental tenet in neuroscience about the shape of axons -- the long, thin filaments radiating from nerve cells that transmit electrical signals from cell to cell – and propose a new model for understanding how information is transmitted in the brain.

6 Dec 2024

Liver conversion of fructose fuels cancer growth by supplying lipids for tumor proliferation

This research highlights the indirect role of fructose in cancer, revealing how liver metabolism enhances tumor growth through lipid-mediated mechanisms.

5 Dec 2024

Fructose consumption linked to accelerated tumor growth in cancer models

Fructose consumption has increased considerably over the past five decades, largely due to the widespread use of high-fructose corn syrup as a sweetener in beverages and ultra-processed foods.

4 Dec 2024

New research sheds light on how monkeys avoid hepatitis B infection

Hepatitis B virus (HBV) infection is a leading cause of chronic liver diseases, that spreads among individuals through blood or body fluids.

4 Dec 2024

Study challenges long-standing understanding of axon structure

Biology textbooks may need a revision, say Johns Hopkins Medicine scientists, who present new evidence that an armlike structure of mammalian brain cells may be a different shape than scientists have assumed for more than a century.

2 Dec 2024

Natural polyphenol boosts mitochondrial function and muscle performance during aging

Oleuropein enhances mitochondrial calcium uptake, reversing age-related declines in muscle function and energy metabolism, with promising clinical potential.

2 Dec 2024

Advanced microscopy reveals how ribosomes attach to mRNA for protein synthesis

Within a cell, DNA carries the genetic code for building proteins. To build proteins, the cell makes a copy of DNA, called mRNA.

28 Nov 2024

Research sheds light on how fat cells safely enlarge to store energy

A team at the Centro Nacional de Investigaciones Cardiovasculares (CNIC), led by Professor Miguel Ángel del Pozo Barriuso, who heads the Mechanoadaptation and Caveolae Biology group at the CNIC, has identified an essential mechanism in fat cells (adipocytes) that enables them to enlarge safely to store energy.

28 Nov 2024

Nanoscale cellular interactions unveiled by the SoTILT3D imaging platform

A team of researchers led by Anna-Karin Gustavsson at Rice University has developed an innovative imaging platform that promises to improve our understanding of cellular structures at the nanoscale.

27 Nov 2024

Scientists develop method to study malaria's sticky proteins

Scientists have unveiled a new tool for studying the highly variable traits that allow malaria parasites to stick to red blood cells and evade the immune system.

26 Nov 2024

New AI model tailors phage treatment for resistant bacterial infections

With the rapid development of antibiotics in the 1930s, phage therapy – using viruses known as bacteriophages or phages to tackle bacterial infections – fell into oblivion.

25 Nov 2024

Study reveals the secret to cellular youth may lie in nucleolus size

The secret to cellular youth may depend on keeping the nucleolus—a condensed structure inside the nucleus of a cell—small, according to Weill Cornell Medicine investigators.

25 Nov 2024

UChicago scientists develop a new approach to study snoRNAs

Dynamic, reversible modifications of DNA and RNA regulate how genes are expressed and transcribed, which can influence cellular processes, disease development, and overall organismal health.

23 Nov 2024

Pioneering protocol sheds light on NMDA receptor distribution in Alzheimer's brains

Researchers from the Institute for Neurosciences (IN), a joint center of the Miguel Hernández University of Elche (UMH) and the Spanish National Research Council (CSIC), who are also part of the Network Center for Biomedical Research in Neurodegenerative Diseases (CIBERNED) and the Alicante Institute for Health and Biomedical Research (ISABIAL), have developed a cellular fractionation protocol.

22 Nov 2024