Nephropathy News and Research

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Nephropathy is a broad medical term used to denote disease or damage of the kidney, which can eventually result in kidney failure. The primary and most obvious functions of the kidney are to excrete any waste products and to regulate the water and acid-base balance of the body – therefore loss of kidney function is a potentially fatal condition.

Complete revascularisation leads to better outcomes in patients with heart attack

In patients being treated for heart attack, complete revascularisation of all significantly blocked arteries leads to better outcomes compared to a strategy of unblocking just the "culprit" artery responsible for the heart attack, according to a new study presented today at ESC Congress 2014.

1 Sep 2014

Lifestyle intervention shows kidney benefits in diabetic patients

A lifestyle intervention focused on weight loss and increasing physical activity should be considered as additional treatment to prevent advanced kidney disease in overweight or obese people with Type 2 diabetes, say researchers.

28 Aug 2014

Calcium buildup in coronary arteries of chronic kidney disease patients indicates heart disease risk

Calcium buildup in the coronary arteries of chronic kidney disease patients may be a strong indicator of heart disease risk, according to a new study in the Journal of the American Society of Nephrology (JASN).

22 Aug 2014

Amgen’s AMG 416 Phase 3 placebo-controlled study meets primary and secondary endpoints

Amgen (NASDAQ: AMGN) today announced that a second placebo-controlled Phase 3 study evaluating AMG 416 for the treatment of secondary hyperparathyroidism (SHPT) in patients with chronic kidney disease (CKD), receiving hemodialysis, met its primary and all secondary endpoints.

19 Aug 2014

Decision Resources expands disease-level coverage of Treatment Algorithms Insight Series

Decision Resources has expanded its disease-level coverage of the Treatment Algorithms Insight Series, which examines U.S. physicians' prescribing behavior, to provide a quantitative analysis of an agent's penetration into each line of therapy.

19 Aug 2014

Meta-analysis shows blood pressure variability and mortality link

A systematic review and meta-analysis of studies investigating the link between visit-to-visit variability of blood pressure and cardiovascular disease or all-cause mortality has revealed a modest, but significant, association.

18 Aug 2014

Nutrition counseling by registered dietitian nutritionist can help prevent or delay diabetes

A new study, indicating that Americans have approximately a 40 percent risk of developing diabetes during their lifetime, offers more evidence that nutrition counseling provided by a registered dietitian nutritionist can help prevent or delay diabetes and its related health problems through lifestyle and dietary changes, according to the Academy of Nutrition and Dietetics.

16 Aug 2014

Phase 2 study: Rigel's R348 fails to meet endpoints in patients with dry eye disease

Rigel Pharmaceuticals, Inc. today announced that R348, its ophthalmic JAK/SYK inhibitor, did not meet the primary or secondary endpoints in a recently completed Phase 2 clinical study in patients with dry eye disease.

13 Aug 2014

Researchers examine skin creams that contains toxic mercury much faster than before

As countries try to rid themselves of toxic mercury pollution, some people are slathering and even injecting creams containing the metal onto or under their skin to lighten it, putting themselves and others at risk for serious health problems.

13 Aug 2014

Longer looks: Kentucky is health law poster child; how to negotiate a lower medical bill; the Ebola outbreak up close

About a year ago, on Aug. 22, a team of inspectors from the Centers for Medicare and Medicaid Services (CMS) unit of the U.S. Department of Health and Human Services arrived in Frankfort, Ky., to see if the people working out of a nondescript warehouse there were going to be able to pull off the launch of Kentucky's Obamacare health-insurance exchange.

8 Aug 2014

Costly specialty drugs drive up Medicare tab

ProPublica and The New York Times look at the explosive spending growth from an obscure medication for treating multiple sclerosis and a rare kidney disease -- and how several top prescribers have links to drugmaker, Questcor Pharmaceuticals.

5 Aug 2014

Diabetes linked to increased head and neck cancer risk

People with diabetes mellitus have a significantly increased risk of developing head and neck cancer compared with those without the condition, show results of a large study conducted in Taiwan.

1 Aug 2014

Salt poses cardiovascular risk in diabetic patients

A diet high in salt increases the risk of cardiovascular disease in patients with Type 2 diabetes, show data from the Japan Diabetes Complications Study.

1 Aug 2014

Southern-style diet results in higher risk of death in patients with chronic kidney disease

New research from the University of Alabama at Birmingham published in the American Journal of Kidney Diseases shows consuming a "Southern-style" diet — consisting of processed meats, fried foods and sugar-sweetened beverages — results in higher risk of death in those with chronic kidney disease.

1 Aug 2014

New version of drug successfully treats lupus in mice

Expanding on his work with a new drug that successfully treated lupus in mice, a biomedical engineer at the University of Houston has received a $250,000 grant to expand his research to a new version of the drug in an effort to treat a wider range of autoimmune diseases.

25 Jul 2014

Randox Cystatin C facilitates early detection and treatment of chronic kidney disease

As a more sensitive maker of renal dysfunction Randox Cystatin C offers several advantages over traditional creatinine assays.

From Randox Laboratories Ltd. 22 Jul 2014

Impact of kidney donation on ability to change life insurance is unknown

People who selflessly step up and donate a kidney can face insurance challenges afterwards, despite the lack of evidence that they have increased health risks.

16 Jul 2014

Rigel initiates Phase 3 clinical program for fostamatinib in patients with ITP

Rigel Pharmaceuticals, Inc. today announced the initiation of a Phase 3 clinical program for its oral SYK inhibitor, fostamatinib, in patients with ITP (immune thrombocytopenic purpura).

16 Jul 2014

Kidney donors often face pointless post-donation hurdles when seeking life insurance

Healthy living kidney donors often face pointless post-donation hurdles when seeking or changing health or life insurance, according to results of a new study by Johns Hopkins researchers.

16 Jul 2014

Researchers create combination drug that controls both tumor growth and metastasis

Researchers at UC Davis, University of Massachusetts and Harvard Medical School have created a combination drug that controls both tumor growth and metastasis. By combining a COX-2 inhibitor, similar to Celebrex, and an epoxide hydrolase (sEH) inhibitor, the drug controls angiogenesis (blood vessel formation), limiting a tumor's ability to grow and spread.

14 Jul 2014

Nephropathy News and Research

Further Reading

Complete revascularisation leads to better outcomes in patients with heart attack

Lifestyle intervention shows kidney benefits in diabetic patients

Calcium buildup in coronary arteries of chronic kidney disease patients indicates heart disease risk

Amgen’s AMG 416 Phase 3 placebo-controlled study meets primary and secondary endpoints

Decision Resources expands disease-level coverage of Treatment Algorithms Insight Series

Meta-analysis shows blood pressure variability and mortality link

Nutrition counseling by registered dietitian nutritionist can help prevent or delay diabetes

Phase 2 study: Rigel's R348 fails to meet endpoints in patients with dry eye disease

Researchers examine skin creams that contains toxic mercury much faster than before

Longer looks: Kentucky is health law poster child; how to negotiate a lower medical bill; the Ebola outbreak up close

Costly specialty drugs drive up Medicare tab

Diabetes linked to increased head and neck cancer risk

Salt poses cardiovascular risk in diabetic patients

Southern-style diet results in higher risk of death in patients with chronic kidney disease

New version of drug successfully treats lupus in mice

Randox Cystatin C facilitates early detection and treatment of chronic kidney disease

Impact of kidney donation on ability to change life insurance is unknown

Rigel initiates Phase 3 clinical program for fostamatinib in patients with ITP

Kidney donors often face pointless post-donation hurdles when seeking life insurance

Researchers create combination drug that controls both tumor growth and metastasis

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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