Omicron News and Research

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Exploring T cell responses during COVID-19 breakthrough infection

Researchers assessed the de novo and recall T cell responses during coronavirus disease 2019 (COVID-19) breakthrough infection.

28 Dec 2022

A genome-based comparison of SARS-CoV-2 XBB recombinant and its parental lineage

In a recent study posted to the bioRxiv* preprint server, researchers in Italy performed a genome-based comparison of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) XBB recombinant with its parental lineages.

27 Dec 2022

An estimated 19 million US adults living with long-COVID

In a recent study published in the journal Clinical Infectious Diseases, a team of researchers examined the risk factors and prevalence and impact of long coronavirus disease (COVID) among a representative sample of adults in the United States (U.S.) and reported that close to 19 million U.S. adults suffer from long COVID.

26 Dec 2022

Exploring plasma and nasal antibody responses to SARS-CoV-2 infection and vaccination

Researchers evaluated plasma and nasal antibody titers responses induced by natural severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and coronavirus disease 2019 (COVID-19) vaccinations among United Kingdom (UK) residents.

23 Dec 2022

Hybrid immunity from mRNA vaccines and breakthrough Omicron infections induces stronger immune responses against Omicron BQ.1.1

Researchers evaluated plasma samples from individuals vaccinated with a fourth booster dose of mono- or bivalent mRNA SARS-CoV-2 vaccine to evaluate the recognition and neutralization capacity against the ancestral (D614G) strain and the Omicron BQ.1.1 subvariant.

23 Dec 2022

High efficacy of SARS-CoV-2 vaccines in preventing COVID-19 deaths in children and adolescents

A new study evaluated the effectiveness of coronavirus disease 2019 (COVID-19) vaccines in Argentinian children when severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Delta and Omicron were predominant.

23 Dec 2022

Beta-containing COVID-19 booster vaccine found to cross-neutralize variants in non-human primates

A new paper presents preliminary evidence that a new vaccine candidate, designed to boost immunity in already immunized individuals, and containing the adjuvanted Beta spike variant protein antigen, can induce a potent cross-neutralizing antibody response in non-human primate models that is detectable for up to three months.

23 Dec 2022

Molnupiravir does not reduce hospitalization or deaths in vaccinated adults with COVID-19, but improves recovery

Molnupiravir (taken as an 800mg dose twice daily for five days) does not reduce hospital admissions or deaths in vaccinated adults with COVID-19 infection who are at higher risk of mortality, according to the results of a randomised controlled trial, published in The Lancet journal.

23 Dec 2022

Children less likely to transmit infectious particles, study finds

Infectious diseases are often transmitted via particles exhaled from infected persons. Yet, the size of such aerosol particles varies greatly, depending on its origin in the respiratory tract.

22 Dec 2022

COVID-19 vaccination protects people with B cell lymphoma and multiple myeloma

A recent Nature Cancer study documented that individuals with B cell lymphomas (LY) and multiple myeloma (MM) developed potent infection neutralization capabilities against several SARS-CoV-2 variants of concern (VoCs).

22 Dec 2022

Bivalent mRNA vaccine is moderately effective in preventing COVID-19

Researchers assesses the real-world efficacy of the novel bivalent COVID-19 vaccine.

22 Dec 2022

T-cell immunity remains effective against SARS-CoV-2 Omicron subvariants

Omicron subvariants effectively escape B-cell immune responses by modifying neutralizing antibody epitopes.

21 Dec 2022

Dutch study shows the effectiveness of COVID vaccination in reducing hospitalizations

The study, which is currently available in the medRxiv* preprint server, reveals that the COVID-19 vaccination has prevented a large number of hospitalizations during the pandemic.

21 Dec 2022

Brazilian model for COVID-19 vaccination reduced severe case and mortality even from variants

A study conducted in Serrana, a small town in São Paulo state used as a model for COVID-19 vaccination in Brazil, shows that mass vaccination reduced the severe case and death rates even while the gamma and delta variants were circulating.

21 Dec 2022

Study: Long COVID has four major subtypes defined by different clusters of symptoms

The post-COVID syndrome known as long COVID has four major subtypes defined by different clusters of symptoms, according to a study led by researchers at Weill Cornell Medicine.

21 Dec 2022

Findings on the origins of the SARS-CoV-2 variant Omicron retracted

On December 1, Charité – Universitätsmedizin Berlin reported new findings on the origins of the SARS-CoV-2 variant Omicron.

20 Dec 2022

Study finds several flavor/fragrance compositions that inhibit vRBD-hACE2 binding

A study describes the antiviral activity of flavor/fragrance compositions against SARS-CoV-2.

20 Dec 2022

Researchers generate a remodeled live-attenuated measles vaccine capable of driving nAb responses against SARS-CoV-2 spike protein

Researchers developed a measles virus (MeV)-vectored vaccine capable of inducing high neutralizing antibody (nAb) responses against SARS-CoV-2.

20 Dec 2022

The effectiveness of a bivalent COVID-19 mRNA booster dose against hospitalization

Researchers reported on the vaccine effectiveness of a bivalent vaccine booster administered after ≥2.0 doses of monovalent mRNA vaccines against COVID-19–related hospitalizations among adult individuals 65.0 years or older.

20 Dec 2022

Study identifies four new monoclonal antibodies with broad neutralizing potencies that target conserved SARS-CoV-2 epitopes

Researchers described four novel monoclonal antibodies with potent and broad neutralization activity against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants, including the current globally dominant Omicron BA.4/BA.5.

20 Dec 2022

Omicron News and Research

Exploring T cell responses during COVID-19 breakthrough infection

A genome-based comparison of SARS-CoV-2 XBB recombinant and its parental lineage

An estimated 19 million US adults living with long-COVID

Exploring plasma and nasal antibody responses to SARS-CoV-2 infection and vaccination

Hybrid immunity from mRNA vaccines and breakthrough Omicron infections induces stronger immune responses against Omicron BQ.1.1

High efficacy of SARS-CoV-2 vaccines in preventing COVID-19 deaths in children and adolescents

Beta-containing COVID-19 booster vaccine found to cross-neutralize variants in non-human primates

Molnupiravir does not reduce hospitalization or deaths in vaccinated adults with COVID-19, but improves recovery

Children less likely to transmit infectious particles, study finds

COVID-19 vaccination protects people with B cell lymphoma and multiple myeloma

Bivalent mRNA vaccine is moderately effective in preventing COVID-19

T-cell immunity remains effective against SARS-CoV-2 Omicron subvariants

Dutch study shows the effectiveness of COVID vaccination in reducing hospitalizations

Brazilian model for COVID-19 vaccination reduced severe case and mortality even from variants

Study: Long COVID has four major subtypes defined by different clusters of symptoms

Findings on the origins of the SARS-CoV-2 variant Omicron retracted

Study finds several flavor/fragrance compositions that inhibit vRBD-hACE2 binding

Researchers generate a remodeled live-attenuated measles vaccine capable of driving nAb responses against SARS-CoV-2 spike protein

The effectiveness of a bivalent COVID-19 mRNA booster dose against hospitalization

Study identifies four new monoclonal antibodies with broad neutralizing potencies that target conserved SARS-CoV-2 epitopes

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