Pathophysiology News and Research

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Joint associations of genetic risk and diet quality with incident type 2 diabetes

Researchers assessed the impact of polygenic scores and diet quality on type 2 diabetes.

3 May 2022

Long COVID is characterized SARS-CoV-2 antigen persistence in the gut mucosa

A new study published in the journal Gastroenterology used upper and lower gastrointestinal endoscopy to assess whether gut antigen persistence leads to post-acute COVID-19 in patients with or without post-acute COVID-19 symptoms.

3 May 2022

Epigenetic abnormalities in hematopoietic cells during fetal development cause idiopathic autism

An international research group led by Professor Toru Takumi (Senior Visiting Scientist, RIKEN Center for Biosystems Dynamics Research) and Researcher Chia-wen Lin at Kobe University Graduate School of Medicine has shown that idiopathic autism is caused by epigenetic abnormalities in hematopoietic cells during fetal development, which results in immune dysregulation in the brain and gut.

2 May 2022

Understanding sex differences in the pathophysiology of SARS-CoV-2 infection

A recent study published in the journal Immunology analyzed whether sex mattered in the immune response to SARS-CoV-2.

29 Apr 2022

Detection of prior SARS-CoV-2 infection by T-cell receptor sequencing

A new study describes a novel COVID-19 detection technique based on T-cell receptor sequencing.

24 Apr 2022

4% patients with COVID-19 shed fecal viral RNA 10 months after diagnosis

Researchers explore how the presence of SARS-CoV-2 RNA in feces can be associated with the presentation of GI symptoms.

24 Apr 2022

Rapid infusion of NaHCO3 bolus after extensive resuscitation leads to higher blood flows to the brain and heart

A new study examines the effect of rapid infusion of 2meq/kg of sodium bicarbonate (NaHCO3) in an ovine model on gas exchange and coronary and cerebral perfusion in the immediate post-resuscitation phase.

22 Apr 2022

Could DNA be linked to Premature Aging in Cancer Survivors?

In this interview, we speak to Dr. Wang about his latest research that investigated accelerated aging in childhood cancer survivors and the underlying genetics causing this.

22 Apr 2022

SARS-CoV-2 spike protein disrupts lipid metabolism resulting in liver, heart & kidney damage

A new study describes the impact of SARS-CoV-2 on host lipid metabolism.

21 Apr 2022

Women with Long COVID-19 syndrome are more symptomatic than men

A new study found that females with Long COVID-19 syndrome were more symptomatic than males. Females were statistically significantly more likely to experience difficulty swallowing, fatigue, chest pain, and palpitations at long-term follow-up, according to a study published in the peer-reviewed Journal of Women's Health.

21 Apr 2022

The involvement of the skeletal muscles in long COVID-19

Researchers reviewed the mechanisms of muscle tissue injury, aggravating conditions, and associated sequelae in long COVID‐19.

18 Apr 2022

SARS-CoV-2 RBD is a selective integrin agonist

Researchers assess the Arg-Gly-Asp (RGD) motif-mediated binding of the SARS-CoV-2 RBD and integrin receptors.

18 Apr 2022

Scientists investigate how gut bacteria directly control the activity of specific neurons

Gut microbiota by-products circulate in the bloodstream, regulating host physiological processes including immunity, metabolism and brain functions.

15 Apr 2022

COVID-19 may affect a group of biochemical reactions called one-carbon metabolism

A new study addresses the relationship between SARS-CoV-2 to the metabolism of one-carbon molecules in the host, suggesting new therapeutic pathways.

13 Apr 2022

Scientific statement from the American Heart Association on COVID-19 and cardiovascular complications in children and adolescents

A recent scientific statement published in Circulation reviewed the current knowledge on COVID-19.

13 Apr 2022

Pathophysiology News and Research

Joint associations of genetic risk and diet quality with incident type 2 diabetes

Long COVID is characterized SARS-CoV-2 antigen persistence in the gut mucosa

Epigenetic abnormalities in hematopoietic cells during fetal development cause idiopathic autism

Understanding sex differences in the pathophysiology of SARS-CoV-2 infection

Detection of prior SARS-CoV-2 infection by T-cell receptor sequencing

4% patients with COVID-19 shed fecal viral RNA 10 months after diagnosis

Rapid infusion of NaHCO3 bolus after extensive resuscitation leads to higher blood flows to the brain and heart

Could DNA be linked to Premature Aging in Cancer Survivors?

SARS-CoV-2 spike protein disrupts lipid metabolism resulting in liver, heart & kidney damage

Women with Long COVID-19 syndrome are more symptomatic than men

The involvement of the skeletal muscles in long COVID-19

SARS-CoV-2 RBD is a selective integrin agonist

Scientists investigate how gut bacteria directly control the activity of specific neurons

COVID-19 may affect a group of biochemical reactions called one-carbon metabolism

Scientific statement from the American Heart Association on COVID-19 and cardiovascular complications in children and adolescents

Development of 18 monoclonal antibodies against 9 SARS-CoV-2 proteins

COVID-19 could change the levels of proteins related to male reproductive function

Study suggests blunted serological responses not responsible for COVID-19 mortality

Insights into the pathophysiology of NeuroCOVID

What are the long-term symptoms of SARS-CoV-2 infection?

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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