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FDA approval provides targeted treatment option for patients with rare DMD mutation

Today, the U.S. Food and Drug Administration granted approval for Amondys 45 (casimersen) injection for the treatment of Duchenne muscular dystrophy (DMD) in patients who have a confirmed mutation of the DMD gene that is amenable to exon 45 skipping (Exons are pieces of DNA that provide information for making proteins in a person's genome).

25 Feb 2021

Researchers create high throughput arrays of miniaturized 3D tumor models

By engineering common filter papers, similar to coffee filters, a team of NYU Abu Dhabi researchers have created high throughput arrays of miniaturized 3D tumor models to replicate key aspects of tumor physiology, which are absent in traditional drug testing platforms.

22 Feb 2021

Researchers use zebrafish to study cancer-immune interactions

Cancer researcher Rita Fior uses zebrafish to study human cancer. Though this may seem like an unlikely match, her work shows great promise with forthcoming applications in personalized medicine.

19 Feb 2021

Researchers identify key genetic changes in interstitial kidney tissue of people with diabetes

Researchers from Indiana University have identified key genetic changes in the interstitial kidney tissue of people with diabetes, a discovery that signifies the potential for a revolutionary new genetic approach to the treatment of kidney disease.

16 Feb 2021

Pitt scientists develop fast, efficient technique for discovering tiny antibody fragments

By capitalizing on a convergence of chemical, biological and artificial intelligence advances, University of Pittsburgh School of Medicine scientists have developed an unusually fast and efficient method for discovering tiny antibody fragments with big potential for development into therapeutics against deadly diseases.

15 Feb 2021

Scientists publish new analysis of most diverse genetic data set

Researchers at the University of Maryland School of Medicine (UMSOM) and their colleagues published a new analysis today in the journal Nature from genetic sequencing data of more than 53,000 individuals, primarily from minority populations.

10 Feb 2021

Drinking one or more cups of caffeinated coffee may reduce heart failure risk

Dietary information from three large, well-known heart disease studies suggests drinking one or more cups of caffeinated coffee may reduce heart failure risk, according to research published today in Circulation: Heart Failure, an American Heart Association journal.

9 Feb 2021

REGENHU announces its participation in the FLAMIN-GO project aimed at developing "personalized" treatments against rheumatoid arthritis

REGENHU announced its participation in the FLAMIN-GO research project aimed at developing an organ-on-chip technology for clinical trials on Rheumatoid Arthritis.

From regenHU Ltd. 4 Feb 2021

Breast cancer‐on‐a‐chip to test the effectiveness of checkpoint inhibitor drugs

There are many mechanisms by which the body responds to foreign invaders. One of these involves the T-cells of the immune system, which have a number of different proteins on their surface called "checkpoint proteins."

2 Feb 2021

Early-life-trauma could affect trajectory of multiple sclerosis development and treatment

Childhood trauma could affect the trajectory of multiple sclerosis development and response to treatment in adulthood, a new study in mice found.

29 Jan 2021

Corning to highlight newest products in 3D cell culture portfolio at SLAS2021

Corning Incorporated will highlight its latest technologies that support the advancement of 3D cell culture, automation, and drug discovery at this year's virtual Society for Laboratory Automation and Screening (SLAS) conference on Jan. 25 through 27.

22 Jan 2021

Researchers discover direct link between placental function and future metabolic disorders

Researchers at the University of Colorado Anschutz Medical Campus have discovered a direct association between placental function in pregnant women and future metabolic disorders in children and adults, a finding that could lead to earlier intervention and diagnosis of disease.

22 Jan 2021

New study helps understand molecular profile of tumors in cancer patients

Researchers from the University Hospitals in Zurich and Basel, ETH Zurich, University of Zurich and the pharmaceutical company Roche have set out to improve cancer diagnostics by developing a platform of state-of-the-art molecular biology methods.

21 Jan 2021

Study offers data related to physicians' potential liability to use AI in personalized medicine

Physicians who follow artificial intelligence (AI) advice may be considered less liable for medical malpractice than is commonly thought, according to a new study of potential jury candidates in the U.S.

11 Jan 2021

Master Regulator proteins control cancer transcriptional identity

Thousands of different genetic mutations have been implicated in cancer, but a new analysis of almost 10,000 patients found that regardless of the cancer's origin, tumors could be stratified in only 112 subtypes and that, within each subtype, the Master Regulator proteins that control the cancer's transcriptional state were virtually identical, independent of the specific genetic mutations of each patient.

11 Jan 2021

A paper-based sensor for detecting COVID-19

News-Medical talks to Dipanjan Pan about the development of a paper-based electrochemical sensor that can detect COVID-19 in less than five minutes.

5 Jan 2021

Scientists identify distinct sub-types of angiosarcomas to allow for targeted treatment

A new study led by clinician-scientists from the National Cancer Centre Singapore, with collaborators from research institutions worldwide, has found that angiosarcomas have unique genomic and immune profiles which allow them to be classified into three different subtypes.

28 Dec 2020

Polygenic risk scores from multi-population data could improve IBD predictions

Using genetic data from nearly 30,000 people, Mount Sinai researchers have built risk scores from a combination of datasets representing distinct ancestral populations that improve prediction of risk for inflammatory bowel diseases (IBD) including Crohn's disease and ulcerative colitis. The study was published in Gastroenterology on December 24.

24 Dec 2020

Study sheds new light on immune system interactions with cancer

Cancers like melanoma are hard to treat, not least because they have a varied bag of tricks for defeating or evading treatments.

21 Dec 2020

£6.7m awarded to find new ways to improve prevention, diagnosis and treatment of diseases

Barts Life Sciences - a partnership between Barts Health NHS Trust and Queen Mary University of London - has been awarded £6.7m by Barts Charity to research new ways to improve the prevention, diagnosis and treatment of a variety of diseases.

18 Dec 2020