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Early-life-trauma could affect trajectory of multiple sclerosis development and treatment

Childhood trauma could affect the trajectory of multiple sclerosis development and response to treatment in adulthood, a new study in mice found.

29 Jan 2021

Corning to highlight newest products in 3D cell culture portfolio at SLAS2021

Corning Incorporated will highlight its latest technologies that support the advancement of 3D cell culture, automation, and drug discovery at this year's virtual Society for Laboratory Automation and Screening (SLAS) conference on Jan. 25 through 27.

22 Jan 2021

Researchers discover direct link between placental function and future metabolic disorders

Researchers at the University of Colorado Anschutz Medical Campus have discovered a direct association between placental function in pregnant women and future metabolic disorders in children and adults, a finding that could lead to earlier intervention and diagnosis of disease.

22 Jan 2021

New study helps understand molecular profile of tumors in cancer patients

Researchers from the University Hospitals in Zurich and Basel, ETH Zurich, University of Zurich and the pharmaceutical company Roche have set out to improve cancer diagnostics by developing a platform of state-of-the-art molecular biology methods.

21 Jan 2021

Study offers data related to physicians' potential liability to use AI in personalized medicine

Physicians who follow artificial intelligence (AI) advice may be considered less liable for medical malpractice than is commonly thought, according to a new study of potential jury candidates in the U.S.

11 Jan 2021

Master Regulator proteins control cancer transcriptional identity

Thousands of different genetic mutations have been implicated in cancer, but a new analysis of almost 10,000 patients found that regardless of the cancer's origin, tumors could be stratified in only 112 subtypes and that, within each subtype, the Master Regulator proteins that control the cancer's transcriptional state were virtually identical, independent of the specific genetic mutations of each patient.

11 Jan 2021

A paper-based sensor for detecting COVID-19

News-Medical talks to Dipanjan Pan about the development of a paper-based electrochemical sensor that can detect COVID-19 in less than five minutes.

5 Jan 2021

Scientists identify distinct sub-types of angiosarcomas to allow for targeted treatment

A new study led by clinician-scientists from the National Cancer Centre Singapore, with collaborators from research institutions worldwide, has found that angiosarcomas have unique genomic and immune profiles which allow them to be classified into three different subtypes.

28 Dec 2020

Polygenic risk scores from multi-population data could improve IBD predictions

Using genetic data from nearly 30,000 people, Mount Sinai researchers have built risk scores from a combination of datasets representing distinct ancestral populations that improve prediction of risk for inflammatory bowel diseases (IBD) including Crohn's disease and ulcerative colitis. The study was published in Gastroenterology on December 24.

24 Dec 2020

Study sheds new light on immune system interactions with cancer

Cancers like melanoma are hard to treat, not least because they have a varied bag of tricks for defeating or evading treatments.

21 Dec 2020

£6.7m awarded to find new ways to improve prevention, diagnosis and treatment of diseases

Barts Life Sciences - a partnership between Barts Health NHS Trust and Queen Mary University of London - has been awarded £6.7m by Barts Charity to research new ways to improve the prevention, diagnosis and treatment of a variety of diseases.

18 Dec 2020

Newly discovered brain pattern could improve the diagnosis of mental health disorders

A pattern in how the brain breaks down tryptophan, a common amino acid consumed through food, was discovered by researchers at The University of Texas Health Science Center at Houston (UTHealth).

18 Dec 2020

Study shows how melanomas assist T cells from identifying and killing tumor cells

Cancers like melanoma are hard to treat, not least because they have a varied bag of tricks for defeating or evading treatments.

17 Dec 2020

4E-BP proteins are key to unlock the antidepressant effect of ketamine in the brain

A group of proteins called 4E-BPs, involved in memory formation, is the key to unlocking the antidepressant effect of ketamine in the brain, according to researchers from three Canadian universities. The discovery could lead to better and safer treatments for certain patients suffering from major depression.

17 Dec 2020

Researchers to investigate why exercise makes some people healthier than others

Why do some people benefit so much from exercise while others enjoy few health gains or even suffer harm? Does age matter when it comes to exercise's health benefits? Are there "molecular signatures" - sets of genes, proteins and other variables ¬- that reveal the answers?

11 Dec 2020

Skin may help to predict future heart problems

Our skin tells us when we've spent too much time in the sun or when the dry air of winter has sucked away too much moisture. Now Jefferson researchers find that the skin can also foretell issues unrelated to the protective barrier.

10 Dec 2020

Study highlights previously unknown mechanisms involved in myeloma resistance

A group of researchers led by Maximillian Merz, MD, Assistant Professor of Oncology with the Myeloma team at Roswell Park Comprehensive Cancer Center, conducted the first prospective clinical trial investigating spatial heterogeneity in patients with either relapsed/refractory or newly diagnosed multiple myeloma.

7 Dec 2020

Study finds surprising link between ALS, FTD and Huntington's disease-associated mutation

A study led by researchers at the National Institutes of Health has made a surprising connection between frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS), two disorders of the nervous system, and the genetic mutation normally understood to cause Huntington's disease.

5 Dec 2020

Improved understanding of exposome-drug interactions could help prescribe effective drug doses

According to scientific estimations, humans are exposed to at least 10,000 to 100,000 environmental and exogenous compounds in an individual lifetime, which are mainly absorbed through our dietary.

2 Dec 2020

Basic concepts lay the foundation for personalized immunotherapy

Personalized Immunotherapy for Tumor Diseases and Beyond introduces personalized immunotherapy with multi-dimensional models of analysis to determine the best plan for the immunotherapy of patients.

23 Nov 2020