Spike Protein News and Research

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The replicative ability and pathogenicity of Omicron BA.4 and BA.5 isolates in hamsters

Researchers characterized the clinical isolates of SARS-CoV-2 Omicron BA.4 and BA.5.

8 Jul 2022

Study suggests spironolactone may improve clinical outcomes in COVID-19

Researchers performed an integrative analysis of clinical outcomes and viral entry networks in severe COVID-19 infection.

8 Jul 2022

The strength and breadth of antibody responses elicited by hybrid immunity to COVID-19 vaccination or infection alone

Researchers assessed neutralizing antibody responses to SARS-CoV-2 after receiving one dose of vaccine.

8 Jul 2022

Antibodies transmitted through breast milk persist six months after COVID mRNA vaccination

Researchers describe the effects of COVID-19 vaccines in lactating mothers and relates their antibody response to the protection of their children.

7 Jul 2022

Vaccine generates antibodies that target SARS-CoV-2 spike protein regions shared among many coronaviruses

Could the SARS-CoV-2 vaccine reawaken previous antibody responses and point the way to a universal coronavirus vaccine? A new analysis of the antibody response to a COVID-19 vaccine suggests the immune system's history with other coronaviruses, including those behind the common cold, shapes the patient's response, according to a study published today in Cell Reports.

6 Jul 2022

Scientists explore mutations in the SARS-CoV-2 receptor-binding domain

Researchers assessed the different mutations of concern in the SARS-CoV-2 receptor-binding domain.

6 Jul 2022

New atomic-level models of spike protein play a key role in COVID-19 infection and immunity

When the coronavirus causing COVID-19 infects human cells, the cell's protein-processing machinery makes modifications to the spike protein that render it more flexible and mobile, which could increase its ability to infect other cells and to evade antibodies, a new study from the University of Illinois Urbana-Champaign found.

6 Jul 2022

Immune response triggered by COVID-19 damages the brain's blood vessels to cause neurological complications

A study from the National Institutes of Health describes the immune response triggered by COVID-19 infection that damages the brain's blood vessels and may lead to short- and long-term neurological symptoms.

5 Jul 2022

Next-generation SARS-CoV-2 nucleocapsid-based vaccines may provide optimal protection against infection

In a new study,researchers suggested the inclusion of nucleocapsid protein in vaccines against SARS-CoV-2.

5 Jul 2022

Brain immune response to SARS-CoV-2 infection

In a recently published article in the journal Current Opinion in Neurobiology, scientists at Washington University School of Medicine, St. Louis have described how immunological alterations associated with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection may impact brain activities and induce acute and post-acute neurological symptoms in coronavirus disease 2019 (COVID-19) patients.

3 Jul 2022

Most therapeutic antibodies for treating COVID-19 patients do not inhibit emerging Omicron subvariants

The Omicron subvariants BA.1 and BA.2 of SARS-CoV-2 have dominated the COVID-19 pandemic in early 2022. In many countries, these viruses are now outcompeted by emerging subvariants, with BA.5 being responsible for the current uptick of cases in Germany.

1 Jul 2022

Scientists develop antibody test to keep track of immunity to SARS-CoV-2 variants

The experts agree - the pandemic is not over. Infections are ticking up again, fueled by the new variants our immune systems are ill prepared for.

1 Jul 2022

Remdesivir resistance in renal transplant patients with long COVID-19

A new study has reported two renal transplant cases, in which individuals, after being exposed to remdesivir, developed a resistance to the drug.

1 Jul 2022

Casirivimab/imdevimab improve outcomes in early COVID-19

A new Viruses study determines the effect of casirivimab/imdevimab on IFN-1 and cytokines during SARS-CoV-2 infection.

29 Jun 2022

SARS-CoV-2 3CLpro also susceptible to mutations

Researchers assess the activity of all potential mutations in the SARS-CoV-2 3CLpro.

29 Jun 2022

Anticancer drug candidate that targets a human protein could be a pan-viral medication

More than two years into the COVID-19 pandemic, people are realizing that the "new normal" will probably involve learning to co-exist with SARS-CoV-2. Some treatments are available, but with new variants emerging, researchers are looking toward new strategies.

29 Jun 2022

Spike Protein News and Research

The replicative ability and pathogenicity of Omicron BA.4 and BA.5 isolates in hamsters

Study suggests spironolactone may improve clinical outcomes in COVID-19

The strength and breadth of antibody responses elicited by hybrid immunity to COVID-19 vaccination or infection alone

Antibodies transmitted through breast milk persist six months after COVID mRNA vaccination

Vaccine generates antibodies that target SARS-CoV-2 spike protein regions shared among many coronaviruses

Scientists explore mutations in the SARS-CoV-2 receptor-binding domain

New atomic-level models of spike protein play a key role in COVID-19 infection and immunity

Immune response triggered by COVID-19 damages the brain's blood vessels to cause neurological complications

Next-generation SARS-CoV-2 nucleocapsid-based vaccines may provide optimal protection against infection

Brain immune response to SARS-CoV-2 infection

Most therapeutic antibodies for treating COVID-19 patients do not inhibit emerging Omicron subvariants

Scientists develop antibody test to keep track of immunity to SARS-CoV-2 variants

Remdesivir resistance in renal transplant patients with long COVID-19

Casirivimab/imdevimab improve outcomes in early COVID-19

SARS-CoV-2 3CLpro also susceptible to mutations

Anticancer drug candidate that targets a human protein could be a pan-viral medication

BNT162b2 COVID vaccine stimulates significant antibody response in lung cancer patients

Acute COVID-19 and vaccination induce cross-reactive antibody responses in breast milk

Study identifies critical genes and biological pathways related to COVID-19 myocarditis

The potential of DNA-based SARS-CoV-2 vaccine candidates

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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