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New MRI contrast agent detects tiny breast cancer tumors, micrometastases

Researchers at Case Western Reserve University have developed a magnetic resonance imaging (MRI) contrast agent that detects much smaller aggressive breast cancer tumors and micrometastases than current agents can identify.

13 Aug 2015

$AbbVie's venetoclax Phase 2 trial meets primary endpoint in patients with relapsed/refractory CLL with 17P deletion$

AbbVie's venetoclax Phase 2 trial meets primary endpoint in patients with relapsed/refractory CLL with 17P deletion

AbbVie, a global biopharmaceutical company, today announced that a Phase 2 trial of its investigational medicine venetoclax met its primary endpoint of achieving overall response rates in patients with relapsed/refractory or previously untreated chronic lymphocytic leukemia (CLL) with 17p deletion, according to an independent review analysis.

12 Aug 2015

New approach may offer improved way to detect early breast cancer

Researchers have shown that magnetic resonance imaging (MRI) can detect the earliest signs of breast cancer recurrence and fast-growing tumors. Their approach detects micromestastases, breakaway tumor cells with the potential to develop into dangerous secondary breast cancer tumors elsewhere in the body.

12 Aug 2015

$Breakdown of fibrin protein essential for bone fracture repair$

Breakdown of fibrin protein essential for bone fracture repair

A team of Vanderbilt investigators has discovered that fibrin, a protein that was thought to play a key role in fracture healing, is not required. Instead, the breakdown of fibrin is essential for fracture repair.

12 Aug 2015

TEAAM trial finds that testosterone has no effect on atherosclerosis progression

Testosterone sales have grown rapidly over the last decade, but few studies have examined the long-term effects of taking testosterone on cardiovascular health and other important outcomes. This week, investigators from Brigham and Women's Hospital report the results of the Testosterone's Effects on Atherosclerosis Progression in Aging Men (TEAAM) trial in the Journal of the American Medical Association.

12 Aug 2015

Total knee replacements can effectively treat degeneration caused by bone deformity

A first-of-its kind study has found that total knee replacements can effectively treat degeneration caused by a bone deformity called Blount disease.

11 Aug 2015

Gamida Cell reaches agreements with FDA and EMA regarding NiCord Phase III study design outline

Gamida Cell, a leader in cellular and immune therapies for the treatment of cancer and orphan genetic diseases, announced today that the company has reached agreements with the FDA and EMA regarding the Phase III study design outline of NiCord.

10 Aug 2015

Turing Pharmaceuticals acquires rights to market Daraprim (pyrimethamine) in the U.S.

Turing Pharmaceuticals AG today announced that it has acquired the exclusive rights to market Daraprim (pyrimethamine) in the U.S. from Impax Laboratories, Inc. The acquisition by Turing is part of a strategic effort focused on treatments for toxoplasmosis and other serious infectious diseases. The company also announced plans to invest in the development of new drug candidates for toxoplasmosis.

10 Aug 2015

Scientists publish new important clues about marrow fat

While most of us worry about the fat cells building up on the fleshy parts of our bodies, scientists have started to pay serious attention to another kind of fat cell deep inside our bones, in what's called the marrow.

7 Aug 2015

Investigational topical drug shows promise in patients with early stage cutaneous T cell lymphoma

Results of a phase one trial show that an investigational topical drug, resiquimod gel, causes regression of both treated and untreated tumor lesions and may completely remove cancerous cells from both sites in patients with early stage cutaneous T cell lymphoma (CTCL) - a rare type of non-Hodgkin lymphoma that affects the skin.

7 Aug 2015

Meniscal transplant surgery reduces pain, improves knee function in most patients younger than age 50

Most patients younger than age 50 with a torn or severely damaged meniscus experienced reduced pain and improved knee function following transplant surgery, according to a study in the August 5 issue of the Journal of Bone and Joint Surgery. However, many patients required additional surgery within 10 years.

6 Aug 2015

Researchers show how realistic environments affect growth of cancer tumors in bones

Researchers at Rice University and University of Texas MD Anderson Cancer Center have developed a way to mimic the conditions under which cancer tumors grow in bones.

6 Aug 2015

Lucideon and ReBioStent project partners to host Bioresorbable Materials for Medical Applications session at ESB 2015

Lucideon, the international materials technology company, along with its partners on the ReBioStent project, will be hosting a satellite session, “Bioresorbable Materials for Medical Applications”, at the European Society of Biomaterials (ESB) conference 2015 in Krakow, Poland on the 2nd of September.

From Lucideon 5 Aug 2015

Imperial Innovations announces launch of pre-clinical spinout company, Orthonika

Imperial Innovations is pleased to announce the launch of Orthonika, a spinout company from Imperial College London that is developing a novel knee meniscus replacement, MenisciKnit.

4 Aug 2015

Researchers explore key factors to improve astronauts’ nutrition needs during space missions

Centuries ago, ships often sailed with crews numbering in the hundreds returning with tens. Cause of death: Scurvy - a severe depletion of Vitamin C.

4 Aug 2015

Study demonstrates significance of EMT as potential therapeutic target for reversing kidney disease

Adults who are worried or terrified sometimes curl up into a fetal position. Likewise, adult cells that are injured, including genetic injury leading to cancer, initiate a process that was present during embryonic development.

4 Aug 2015

Engineered protein shown effective in patients with severe von Willebrand disease

The first protein engineered to help control bleeding episodes in patients with severe von Willebrand disease (vW disease) has been shown to be safe and effective, according to results of a Phase III trial.

4 Aug 2015

UVA Stem Cell Transplant Program receives FACT accreditation for autologous and allogeneic transplants

The Stem Cell Transplant Program at the University of Virginia Cancer Center has received international accreditation for its use of stem cells and bone marrow to treat patients with blood cancers.

3 Aug 2015

Array Biopharma reports strong fourth quarter and full year 2015 financial results

Array BioPharma Inc. today reported results for the fourth quarter and full year of its fiscal year ended June 30, 2015.

3 Aug 2015

Zimmer Biomet announces financial results for Q2 2015

Zimmer Biomet Holdings, Inc. today reported financial results for the quarter ended June 30, 2015. The Company reported second quarter net sales of $1.17 billion, a decrease of 1.3% reported and an increase of 5.7% constant currency compared to the second quarter of 2014.

30 Jul 2015

Bone News and Research

New MRI contrast agent detects tiny breast cancer tumors, micrometastases

AbbVie's venetoclax Phase 2 trial meets primary endpoint in patients with relapsed/refractory CLL with 17P deletion

New approach may offer improved way to detect early breast cancer

Breakdown of fibrin protein essential for bone fracture repair

TEAAM trial finds that testosterone has no effect on atherosclerosis progression

Total knee replacements can effectively treat degeneration caused by bone deformity

Gamida Cell reaches agreements with FDA and EMA regarding NiCord Phase III study design outline

Turing Pharmaceuticals acquires rights to market Daraprim (pyrimethamine) in the U.S.

Scientists publish new important clues about marrow fat

Investigational topical drug shows promise in patients with early stage cutaneous T cell lymphoma

Meniscal transplant surgery reduces pain, improves knee function in most patients younger than age 50

Researchers show how realistic environments affect growth of cancer tumors in bones

Lucideon and ReBioStent project partners to host Bioresorbable Materials for Medical Applications session at ESB 2015

Imperial Innovations announces launch of pre-clinical spinout company, Orthonika

Researchers explore key factors to improve astronauts’ nutrition needs during space missions

Study demonstrates significance of EMT as potential therapeutic target for reversing kidney disease

Engineered protein shown effective in patients with severe von Willebrand disease

UVA Stem Cell Transplant Program receives FACT accreditation for autologous and allogeneic transplants

Array Biopharma reports strong fourth quarter and full year 2015 financial results

Zimmer Biomet announces financial results for Q2 2015

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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