Clinical Trial News and Research

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Highly focused radiation may slow disease progression in men with oligometastatic prostate cancer

Highly focused, intense doses of radiation called stereotactic ablative radiation (SABR) may slow progression of disease in a subset of men with hormone-sensitive prostate cancers that have spread to a few separate sites in the body, according to results of a phase II clinical trial of the therapy.

26 Mar 2020

Murdoch Children's Research Institute to roll-out clinical trial of BCG vaccine against COVID-19

Professor Kathryn North AC, Director of the Murdoch Children's Research Institute in Melbourne, Australia, has announced its infectious disease researchers are preparing to roll-out a multi-center randomized controlled clinical trial of the BCG vaccine against COVID-19.

26 Mar 2020

Intense and targeted radiotherapy could slow progression of certain prostate cancers

Targeted and strong doses of stereotactic ablative radiation (SABR) radiotherapy could slow progression in prostate cancer.

26 Mar 2020

Despite failures, chemotherapy still promising against fatal pediatric brain cancer

The pediatric brain cancer known as diffuse intrinsic pontine glioma is almost uniformly fatal. In part, this is due to where and how it grows, forming as a diffuse net of cells in a part of the brainstem called the pons, which controls essential functions like breathing and swallowing.

25 Mar 2020

Highly purified fish oil therapy could prevent thousands of cardiovascular events

Researchers from the University of California, Irvine have conducted a statistical analysis that predicts more than 70,000 heart attacks, strokes and other adverse cardiovascular events could be prevented each year in the U.S. through the use of a highly purified fish oil therapy.

25 Mar 2020

German scientists test TB vaccine against coronavirus

The coronavirus disease (COVID-19) had taken a toll on the world, affecting 168 countries and more than 417,000 people. So far, more than 18,600 people have died due to complications of the disease. Scientists across the globe race to develop the first vaccine against the novel coronavirus.

24 Mar 2020

Researchers propose a stopgap measure to help Covid-19 patients in respiratory distress

Researchers at MIT and the University of Colorado at Denver have proposed a stopgap measure that they believe could help Covid-19 patients who are in acute respiratory distress.

24 Mar 2020

Clinical trial launched to investigate safety and efficacy of antiviral drug for COVID-19

Physician-scientists at four University of California Health medical centers -- UC San Diego Health, UC San Francisco, UC Irvine Health and UC Davis Health -- have begun recruiting participants for a Phase II clinical trial to investigate the safety and efficacy of treating adult patients with COVID-19 with remdesivir, an antiviral drug that has shown activity in animal models and human clinical trials of SARS-CoV, MERS-CoV, Ebola, Marburg and other viruses.

24 Mar 2020

Projects to develop COVID-19 vaccines receive U.K. gov’t funding

The U.K. government backs six projects aimed to fight the coronavirus outbreak, promising $23 million (£20 million) in funding. The projects, including two focused on vaccination trials, will help fast track the development of a vaccine to stop the spread of the coronavirus, leading to the death of more than 16,500 people across the globe.

24 Mar 2020

First patients enrolled in new clinical trial to evaluate potential COVID-19 treatments

Researchers from the University of Oxford have launched a new clinical trial to test the effects of potential drug treatments for patients admitted to hospital with COVID-19. The first patients have now been recruited.

23 Mar 2020

UNC researchers look to NGS for better understanding of COVID-19

It might be the future of diagnostic testing for common infections, and could prove to be a crucial tool for understanding and fighting novel viruses.

23 Mar 2020

Using 'young NK cells' could improve the effectiveness of immunotherapy for cancer patients

Immunotherapy that involves treating cancer with the body's own immune cells, or those of a matched donor, shows promise in clinical trials for some patients, but not all.

22 Mar 2020

As coronavirus spreads widely, millions of older Americans live in counties with no ICU beds

More than half the counties in America have no intensive care beds, posing a particular danger for more than 7 million people who are age 60 and up - older patients who face the highest risk of serious illness or death from the rapid spread of COVID-19, a Kaiser Health News data analysis shows.

20 Mar 2020

Lopinavir and ritonavir drug combo tested in severe COVID-19

Researchers from China and the United Kingdom have collaborated to conduct a clinical trial looking at the efficacy of a combination of two anti-HIV drugs lopinavir and ritonavir to combat severe cases of COVID-19. Their study titled, “A Trial of Lopinavir–Ritonavir in Adults Hospitalized with Severe COVID-19,” was published in the latest issue of the New England Journal of Medicine (NEJM).

19 Mar 2020

Milken Institute launches vaccine development and treatment tracker for COVID-19

The Milken Institute is launching a resource to help the public and policymakers track progress in the development of treatments and vaccines for COVID-19.

19 Mar 2020

Study helps predict which ovarian cancer patients will not benefit from immune-PARP combo

In patients with advanced ovarian cancer, a combination of drugs known as immune checkpoint inhibitors and PARP inhibitors can produce powerful remissions, clinical trials have shown, but up until now investigators haven't been able to predict which patients won't benefit from the treatment and should explore other options.

19 Mar 2020

Study paves way for identifying ovarian cancer patients who will not benefit from combination therapy

A study suggests it may be possible to identify those who will not benefit from drug combination for advanced ovarian cancer.

19 Mar 2020

Researchers identify new way to treat Danon disease using gene therapy

Danon disease is a very rare, life-threatening condition where the fundamental biological process of removing and recycling proteins does not work.

18 Mar 2020

C-Path and Lundbeck join hands to improve scientific community's insight in Alzheimer's

The Critical Path Institute and H. Lundbeck A/S are proud to announce that they will work together to significantly improve the scientific community's insight in Alzheimer's disease through Lundbeck's contribution of a unique set of clinical trial data from more than 2,500 AD patients to the Critical Path for Alzheimer's Disease consortium's integrated database for qualified researchers across the globe to access.

18 Mar 2020

Vaxxas' novel high-density microarray patch can deliver vaccines safely and effectively

Vaxxas, a clinical-stage biotechnology company commercializing a novel vaccination platform, today announced the publication in the journal PLoS Medicine of groundbreaking clinical research indicating the broad immunological and commercial potential of Vaxxas' novel high-density microarray patch.

17 Mar 2020

Clinical Trial News and Research

Highly focused radiation may slow disease progression in men with oligometastatic prostate cancer

Murdoch Children's Research Institute to roll-out clinical trial of BCG vaccine against COVID-19

Intense and targeted radiotherapy could slow progression of certain prostate cancers

Despite failures, chemotherapy still promising against fatal pediatric brain cancer

Highly purified fish oil therapy could prevent thousands of cardiovascular events

German scientists test TB vaccine against coronavirus

Researchers propose a stopgap measure to help Covid-19 patients in respiratory distress

Clinical trial launched to investigate safety and efficacy of antiviral drug for COVID-19

Projects to develop COVID-19 vaccines receive U.K. gov’t funding

First patients enrolled in new clinical trial to evaluate potential COVID-19 treatments

UNC researchers look to NGS for better understanding of COVID-19

Using 'young NK cells' could improve the effectiveness of immunotherapy for cancer patients

As coronavirus spreads widely, millions of older Americans live in counties with no ICU beds

Lopinavir and ritonavir drug combo tested in severe COVID-19

Milken Institute launches vaccine development and treatment tracker for COVID-19

Study helps predict which ovarian cancer patients will not benefit from immune-PARP combo

Study paves way for identifying ovarian cancer patients who will not benefit from combination therapy

Researchers identify new way to treat Danon disease using gene therapy

C-Path and Lundbeck join hands to improve scientific community's insight in Alzheimer's

Vaxxas' novel high-density microarray patch can deliver vaccines safely and effectively

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