Clinical Trial News and Research

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Trial of cancer drug OxaliTex promises lower toxicity and more robust action

Preclinical trials indicate that a drug candidate called OxaliTex can stop the growth of cancer cells completely. OxaliTex appears to be more potent than many other common chemotherapy drugs, with less toxicity and less rapidly counteracted by mechanisms of drug resistance. The study was reported in the journal Proceedings of the National Academy of Sciences in March 2020.

16 Mar 2020

mRNA vaccine against novel coronavirus goes on a trial in Seattle

A clinical trial for a vaccine to protect against the novel coronavirus commenced this Monday in the U.S.. If successful, this could mean an end to the current global pandemic of COVID-19 infections, feel experts.

16 Mar 2020

New method could help facilitate transition of medical technology from lab to market

Advances in materials, microfabrication and medical imaging are accelerating the pace of innovation in implantable neuroprosthetics.

16 Mar 2020

Triple therapies effective and safe in malaria

A new study describing the outcome of a clinical trial of two malaria treatment protocols involving the use of triple therapies based on artemisinin reports their high efficacy and low adverse effects.

12 Mar 2020

UK lab looks for volunteers to be infected with coronavirus

Amid the coronavirus disease (COVID-19) pandemic, scientists are asking for healthy volunteers to help in the development of the vaccine. Volunteers will be infected with the two strains of the common coronavirus.

12 Mar 2020

Fight for Sight funded researcher develops gene therapy approach for glaucoma

A Fight for Sight funded researcher from the University of Bristol has used gene editing techniques to successfully demonstrate a gene therapy for glaucoma in the lab, in results published in Molecular Therapy in March.

11 Mar 2020

Newer antiretroviral drugs may be the safest, most effective HIV treatment during pregnancy

The antiretroviral drugs dolutegravir and emtricitabine/tenofovir alafenamide fumarate (DTG+FTC/TAF) may comprise the safest and most effective HIV treatment regimen currently available during pregnancy, researchers announced today.

11 Mar 2020

Genetic test could help doctors to identify patients with ultra high risk multiple myeloma

A new genetic test could help doctors pick out patients with the bone marrow cancer multiple myeloma who are at 'ultra high risk' of their cancer progressing aggressively early on.

10 Mar 2020

Music appears to decrease delirium in critically ill patients

It is common for critically ill patients on life support to develop delirium, a form of acute brain failure for which no effective treatment is known.

10 Mar 2020

Research reveals bias and stereotyping when recruiting patients for oncology clinical trials

New research reveals bias and stereotyping among clinical and research professionals who recruit patients to enroll in cancer clinical trials. The findings are published early online in CANCER, a peer-reviewed journal of the American Cancer Society.

10 Mar 2020

New approach to stimulate immune cells may provide better protection against Alzheimer's

Scientists at the German Center for Neurodegenerative Diseases, the Ludwig-Maximilians-Universitaet Munich and Denali Therapeutics (South San Francisco, CA, USA) have developed an approach to stimulate immune cells of the brain in such a way that they might possibly provide better protection against Alzheimer's disease.

10 Mar 2020

Clinical trial evaluates effectiveness of spinal cord stimulation in patients with overactive bladder

Keck Medicine of USC urologists are launching a clinical trial to evaluate the effectiveness of spinal cord stimulation in patients with an overactive bladder due to neurological conditions, such as a spinal cord injury or stroke, and idiopathic (unknown) causes.

10 Mar 2020

How effective is Gabapentin in alcohol use disorder?

A new study published in the journal JAMA Internal Medicine in March 2020 reports the striking efficacy of the drug gabapentin in helping people with alcohol use disorder (AUD) with their alcohol withdrawal symptoms.

9 Mar 2020

PrEP drug levels found to lower among pregnant African adolescent girls and young women

Among African adolescent girls and young women who took HIV pre-exposure prophylaxis (PrEP) daily, levels of the PrEP drug tenofovir were more than 30% lower in those who were pregnant than in those who had recently given birth.

9 Mar 2020

New model of glucose-responsive insulin could lead to better treatment for diabetes

One promising new strategy to treat diabetes is to give patients insulin that circulates in their bloodstream, staying dormant until activated by rising blood sugar levels.

9 Mar 2020

Investigational CAR-T therapy for Hodgkin lymphoma receives fast-track designation from FDA

Based on proof-of-concept results from clinical trials at University of North Carolina Lineberger Comprehensive Cancer Center and Baylor College of Medicine, an investigational cellular immunotherapy for Hodgkin lymphoma has received a Regenerative Medicine Advanced Therapy designation from the U.S. Food and Drug Administration.

9 Mar 2020

Study reveals bias and stereotyping when enrolling patients in cancer clinical trials

New research reveals bias and stereotyping among clinical and research professionals who recruit patients to enroll in cancer clinical trials.

9 Mar 2020

New 'Immuno-Engineering to Improve Immunotherapy' Center formed to advance cancer therapy

Harvard University's Wyss Institute of Biologically Inspired Engineering and its collaborating institutions, the Harvard John A. Paulson School of Engineering and Applied Sciences, Dana-Farber Cancer Institute, and Harvard's Department of Stem Cell and Regenerative Biology, announce the formation of a new NIH-funded Immuno-Engineering to Improve Immunotherapy Center.

7 Mar 2020

Aggressive features in papillary thyroid microcarcinoma raises the risk for distant metastasis

Although papillary thyroid carcinoma is the most common form of thyroid malignancy, it is considered to be an indolent disease that progresses slowly and has an excellent prognosis.

6 Mar 2020

The Pancreatic Cancer Collective awards additional funding of $16 million for new therapies

The Pancreatic Cancer Collective, the strategic partnership of Lustgarten Foundation and Stand Up To Cancer, has awarded additional funding of up to $16 million to four teams of top researchers as part of its "New Therapies Challenge Grants," the American Association for Cancer Research, Scientific Partner of SU2C, announced today.

5 Mar 2020

Clinical Trial News and Research

Trial of cancer drug OxaliTex promises lower toxicity and more robust action

mRNA vaccine against novel coronavirus goes on a trial in Seattle

New method could help facilitate transition of medical technology from lab to market

Triple therapies effective and safe in malaria

UK lab looks for volunteers to be infected with coronavirus

Fight for Sight funded researcher develops gene therapy approach for glaucoma

Newer antiretroviral drugs may be the safest, most effective HIV treatment during pregnancy

Genetic test could help doctors to identify patients with ultra high risk multiple myeloma

Music appears to decrease delirium in critically ill patients

Research reveals bias and stereotyping when recruiting patients for oncology clinical trials

New approach to stimulate immune cells may provide better protection against Alzheimer's

Clinical trial evaluates effectiveness of spinal cord stimulation in patients with overactive bladder

How effective is Gabapentin in alcohol use disorder?

PrEP drug levels found to lower among pregnant African adolescent girls and young women

New model of glucose-responsive insulin could lead to better treatment for diabetes

Investigational CAR-T therapy for Hodgkin lymphoma receives fast-track designation from FDA

Study reveals bias and stereotyping when enrolling patients in cancer clinical trials

New 'Immuno-Engineering to Improve Immunotherapy' Center formed to advance cancer therapy

Aggressive features in papillary thyroid microcarcinoma raises the risk for distant metastasis

The Pancreatic Cancer Collective awards additional funding of $16 million for new therapies

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