Epidemiology News and Research

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Research brief provides clinical validation of LOXO-101 Phase 1 trial for treatment of TRK fusion cancer

The University of Colorado Cancer Center and Loxo Oncology, Inc., a biopharmaceutical company focused on the discovery, development and commercialization of targeted cancer therapies, today announced the publication of a research brief in the online edition of the journal Cancer Discovery, describing the first patient with a tropomyosin receptor kinase fusion cancer enrolled in the Phase 1 dose escalation trial of LOXO-101, the only selective TRK inhibitor in clinical development.

28 Jul 2015

Europe has increasing prevalence of fungal resistance, warns ESCMID

The European Society of Clinical Microbiology and Infectious Disease – an organization that explores the risks and best practices in infectious disease – is imploring global healthcare professionals and bodies to take a more active role in the growing problem of fungal resistance.

28 Jul 2015

Research brief describes enrollment of first patient with TRK fusion cancer in LOXO-101 Phase 1 trial

The University of Colorado Cancer Center and Loxo Oncology, Inc., a biopharmaceutical company focused on the discovery, development and commercialization of targeted cancer therapies, today announced the publication of a research brief in the online edition of the journal Cancer Discovery, describing the first patient with a tropomyosin receptor kinase (TRK) fusion cancer enrolled in the Phase 1 dose escalation trial of LOXO-101, the only selective TRK inhibitor in clinical development.

28 Jul 2015

New special issue addresses hottest areas of research in cancer and metabolism

The latest Special Issue in ecancermedicalscience collects four original articles from experts in cancer and metabolism, addressing the hottest areas of research in this rapidly developing field.

25 Jul 2015

Prostate cancer patients more likely to receive medical care matched to level of risk

After decades of overtreatment for low-risk prostate cancer and inadequate management of its more aggressive forms, patients are now more likely to receive medical care matched to level of risk, according to a study by researchers at UC San Francisco.

25 Jul 2015

Adults born very premature display socially withdrawn personality

New research indicates that adults born very premature are more likely to be socially withdrawn and display signs of autism.

24 Jul 2015

V-PPRN approved to receive $1.4 million to participate in second phase of PCORnet

The Vasculitis Patient-Powered Research Network, led by Peter A. Merkel, MD, MPH, Professor of Medicine and Epidemiology at the University of Pennsylvania and George Casey, MBA, Vice President of the Vasculitis Foundation, has been approved to receive a three-year $1.4 million award by the Patient-Centered Outcomes Research Institute as part of the second phase of the National Patient-Centered Clinical Research Network.

24 Jul 2015

Researchers question benefits of deworming intervention in school-age children

Deworming children may not improve school attendance and the evidence that informs international policy needs to be re-appraised following a major re-analysis by researchers at the London School of Hygiene & Tropical Medicine.

24 Jul 2015

UTHealth's Kayo Fujimoto awarded grant to study genetic and social aspects of HIV transmission

Kayo Fujimoto, Ph.D., assistant professor in the Center for Health Promotion and Prevention Research at The University of Texas Health Science Center at Houston School of Public Health, has been awarded a grant to study the genetic and social network aspects of human immunodeficiency virus (HIV) transmission.

24 Jul 2015

Experts draft prescription for making cancer drugs more affordable

A group of 118 of the nation's leading cancer experts have drafted a prescription for reducing the high cost of cancer drugs and voiced support for a patient-based grassroots movement demanding action on the issue. Their recommendations and support are outlined in a commentary, co-authored by the group, in the journal Mayo Clinic Proceedings.

23 Jul 2015

Late- and post-menopausal women have more fat around hearts compared to pre-menopausal counterparts

Late- and post-menopausal women have significantly greater volumes of fat around their hearts - a risk factor for heart disease - than their pre-menopausal counterparts, a University of Pittsburgh Graduate School of Public Health study has shown for the first time.

23 Jul 2015

Research suggests that only one in three older Americans have diabetes under control

Only one in three older Americans have their diabetes under control as measured by guidelines set by the American Diabetes Association, new Johns Hopkins Bloomberg School of Public Health research suggests.

22 Jul 2015

Study: Cash to stay in school did not reduce HIV risk among young women in South Africa

A Phase III, individually randomized trial has found conditional cash transfers for school attendance did not reduce the risk of HIV among high-school aged women in South Africa, investigators from the HIV Prevention Trials Network (HPTN) reported today at the 8th International AIDS Society (IAS) Conference on HIV Pathogenesis, Treatment and Prevention in Vancouver, Canada.

22 Jul 2015

Woman's weight during first pregnancy can negatively affect second baby

A woman's weight during her first pregnancy can affect how her second baby fares, Saint Louis University research finds.

21 Jul 2015

New UTMB study finds no association between testosterone therapy and blood clots in veins

A new study from The University of Texas Medical Branch at Galveston of more than 30,000 commercially insured men is the first large comparative analysis to show that there is no link between testosterone therapy and blood clots in veins. The study found that middle-aged and older men who receive testosterone therapy are not at increased risk of this illness.

21 Jul 2015

New issue of FMCH Journal examines evidence-based population health and patient care

Evidence-Based Approaches to Population Health and Family Practice is the theme of the new issue of Family Medicine and Community Health, an international peer reviewed medical journal with editorial offices in China and the U.S. The Summer 2015 issue includes six original research articles, two educational research articles and two systematic reviews addressing various topics in evidence based population health and patient care.

17 Jul 2015

Air pollution from wildfires may heighten risk of heart-related incidents

Air pollution from wildfires may increase risk of cardiac arrests, and other sudden acute heart problems, researchers have found.

17 Jul 2015

Einstein-Montefiore researchers to present multiple findings at Alzheimer's Association International Conference

Investigators at Montefiore Health System and Albert Einstein College of Medicine of Yeshiva University will present multiple findings at the Alzheimer's Association International Conference, taking place July 18-23 in Washington, D.C. Research topics include risk factors for developing amnestic mild cognitive impairment (aMCI)—a condition characterized by memory problems, and is most often a precursor of Alzheimer's dementia.

16 Jul 2015

Big data project: CWRU wins federal grant to develop platform for collection, analysis of clinical data

Case Western Reserve University is one of three institutions nationwide to win federal 'big data' grants focused on developing ways to ensure the integrity and comparability of the reams of information the U.S. health care system collects every day. If successful, the work could create enormous new opportunities to glean insights that help physicians cure or even prevent illness and disease.

16 Jul 2015

Depression, urinary incontinence magnify effects of vaginal symptoms in postmenopausal women

Special efforts should be made to identify and treat depression and urinary incontinence in postmenopausal women with vaginal symptoms, according to UC San Francisco researchers, as these two common conditions not only tend to co-exist with vaginal symptoms but also may complicate the impact of these symptoms on women's daily activities and quality of life.

16 Jul 2015

Epidemiology News and Research

Research brief provides clinical validation of LOXO-101 Phase 1 trial for treatment of TRK fusion cancer

Europe has increasing prevalence of fungal resistance, warns ESCMID

Research brief describes enrollment of first patient with TRK fusion cancer in LOXO-101 Phase 1 trial

New special issue addresses hottest areas of research in cancer and metabolism

Prostate cancer patients more likely to receive medical care matched to level of risk

Adults born very premature display socially withdrawn personality

V-PPRN approved to receive $1.4 million to participate in second phase of PCORnet

Researchers question benefits of deworming intervention in school-age children

UTHealth's Kayo Fujimoto awarded grant to study genetic and social aspects of HIV transmission

Experts draft prescription for making cancer drugs more affordable

Late- and post-menopausal women have more fat around hearts compared to pre-menopausal counterparts

Research suggests that only one in three older Americans have diabetes under control

Study: Cash to stay in school did not reduce HIV risk among young women in South Africa

Woman's weight during first pregnancy can negatively affect second baby

New UTMB study finds no association between testosterone therapy and blood clots in veins

New issue of FMCH Journal examines evidence-based population health and patient care

Air pollution from wildfires may heighten risk of heart-related incidents

Einstein-Montefiore researchers to present multiple findings at Alzheimer's Association International Conference

Big data project: CWRU wins federal grant to develop platform for collection, analysis of clinical data

Depression, urinary incontinence magnify effects of vaginal symptoms in postmenopausal women

Industry Focus: Infectious Diseases eBook

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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