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WPI researchers awarded $1.3 million NIH grant to study use of copper to battle bacterial invader

Copper is an essential micronutrient that all organisms need to maintain healthy metabolism. But unless it is bound to proteins, copper is also toxic to cells. With a $1.3 million award from the National Institutes of Health, researchers at Worcester Polytechnic Institute will conduct a systematic study of copper in the bacteria Pseudomonas aeruginosa (P. aeruginosa), a leading cause of hospital-associated infections that is increasingly resistant to antibiotics, with the hope of discovering new drug targets that might allow cells in the body to use copper to fight back against this bacterial invader.

25 Nov 2015

Scientists create detailed image of deadly toxin linked to bacterial pneumonia, meningitis, septicaemia

Scientists from the University of Leicester have for the first time created a detailed image of a toxin - called pneumolysin - associated with deadly infections such as bacterial pneumonia, meningitis and septicaemia.

25 Nov 2015

Green Cross' Biologics License Application for IVIG-SN submitted to FDA

Green Cross Corporation, a South Korean biopharmaceutical company, today announced that it has submitted its Biologics License Application for IVIG-SN (human normal immunoglobulin G for intravenous administration) to the United States Food and Drug Administration.

24 Nov 2015

Oxford University researchers unlock the secret behind bacterial sex

Migration between different communities of bacteria is the key to the type of gene transfer that can lead to the spread of traits such as antibiotic resistance, according to researchers at Oxford University.

23 Nov 2015

Prevalence of antimicrobial resistance in horses, other companion animals may impact human health

Bacterial resistance to antimicrobial agents is a significant problem for both human and veterinary medicine, but little research has been done on the prevalence or mechanisms of resistance in horses and other companion animals, and how such resistance might impact human health.

23 Nov 2015

U of T researchers discover mysterious fungus that defends against neighbouring bacteria

Researchers at the University of Toronto examined fungi in the mucus of patients with cystic fibrosis and discovered how one particularly cunning fungal species has evolved to defend itself against neighbouring bacteria.

21 Nov 2015

Innovative microbiome technology may help fight certain infections

Stony Brook University and Ortek Therapeutics, Inc. announced today that two patent applications were filed in the United States and internationally for nutrient based compositions utilizing an innovative microbiome technology that may help combat certain infections.

20 Nov 2015

Last resort antibiotics may no longer work

E.coli has become resistant to the last line of antibiotics we have left and untreatable bugs may already be circulating in Britain, warn scientists.

19 Nov 2015

New technique improves accuracy of CRISPR/Cas9 gene editing system

A new CRISPR/Cas9 technology developed by scientists at the University of Massachusetts Medical School is precise enough to surgically edit DNA at nearly any genomic location, while avoiding potentially harmful off-target changes typically seen in standard CRISPR gene editing techniques.

19 Nov 2015

Houston Methodist invention named one of 100 most innovative technologies by R&D Magazine

R&D Magazine named the handheld single-cell pipette (hSCP), a Houston Methodist Research Institute invention, as one the 100 most innovative technologies and services of the past year.

19 Nov 2015

Giving antibiotics early can reduce risk of severe lower respiratory tract illness in children

Respiratory infections are common in preschoolers, but while most children recover fairly easily from the typical coughs and congestion, a significant number develop illnesses severe enough to interfere with breathing and warrant trips to urgent care clinics or emergency rooms.

18 Nov 2015

RNA-based drugs provide many advantages over CRISPR/Cas9 gene editing system

In just the past few years, researchers have found a way to use a naturally occurring bacterial system known as CRISPR/Cas9 to inactivate or correct specific genes in any organism. CRISPR/Cas9 gene editing activity runs continuously, though, leading to risk of additional editing at unwanted sites. Now, researchers at University of California, San Diego School of Medicine, Ludwig Cancer Research and Isis Pharmaceuticals demonstrate a commercially feasible way to use RNA to turn the CRISPR-Cas9 system on and off as desired -- permanently editing a gene, but only temporarily activating CRISPR-Cas9.

17 Nov 2015

Birmingham researchers identify how Salmonella infections can lead to life-threatening thrombosis

Researchers from the University of Birmingham have, for the first time, identified how Salmonella infections that have spread to our blood and organs can lead to life-threatening thrombosis.

17 Nov 2015

Scientists show how absence of microbiota has remarkable effect against obesity

In the past few years, research on gut microbiota (that is, all microorganisms, mainly bacteria, inhabiting our gut) has started to unravel its tremendous role in our body, and how it symbiotically affects the functioning of our organs. In particular, microbiota has also an impact on the way calories are absorbed and how fat cells develop.

17 Nov 2015

Helmholtz Centre for Infection Research scientists identify promising antitumor agent

Support comes out of the ground: Scientists from the Helmholtz Centre for Infection Research in Germany have identified a terrestrial myxobacterium as a promising source for the bengamide class of natural products, which were originally thought to be secondary metabolites of marine sponges only.

17 Nov 2015

Pathophysiological biomarkers predict PAH prognosis

Researchers have identified three biomarkers that signify an increased risk of death or requirement for lung transplantation in patients with pulmonary arterial hypertension.

13 Nov 2015

Entirely new enzymatic process of DNA synthesis

Cleaver Scientific has supplied a UV Sterilization Cabinet to Touchlight Genetics (Hampton, UK) who had sought a sterile workspace for the preparation of their RNA and DNA samples and templates.

From Cleaver Scientific Ltd 12 Nov 2015

New research uncovers antibiotic prescription trends across England

New research by Antibiotic Research UK, the world’s first charity created to develop new antibiotics in the fight against superbugs, and high-performance analytic database company EXASOL has discovered that while the number of antibiotic prescriptions is coming down across England, GP practices in the most deprived parts of the country are prescribing 20% more and, worryingly, antibiotic prescriptions are on the increase in these deprived areas.

12 Nov 2015

Some gut microbes may hold the key to regulating good health, say Oregon scientists

University of Oregon scientists have found that strength in numbers doesn't hold true for microbes in the intestines. A minority population of the right type might hold the key to regulating good health.

12 Nov 2015

Intravenous PEG-asparaginase use recommended in paediatric ALL

Phase III trial results support the use of intravenously administered PEGylated Escherichia coli asparaginase as the preparation of choice in children and adolescents with acute lymphoblastic leukaemia.

11 Nov 2015

Bacterial News and Research

WPI researchers awarded $1.3 million NIH grant to study use of copper to battle bacterial invader

Scientists create detailed image of deadly toxin linked to bacterial pneumonia, meningitis, septicaemia

Green Cross' Biologics License Application for IVIG-SN submitted to FDA

Oxford University researchers unlock the secret behind bacterial sex

Prevalence of antimicrobial resistance in horses, other companion animals may impact human health

U of T researchers discover mysterious fungus that defends against neighbouring bacteria

Innovative microbiome technology may help fight certain infections

Last resort antibiotics may no longer work

New technique improves accuracy of CRISPR/Cas9 gene editing system

Houston Methodist invention named one of 100 most innovative technologies by R&D Magazine

Giving antibiotics early can reduce risk of severe lower respiratory tract illness in children

RNA-based drugs provide many advantages over CRISPR/Cas9 gene editing system

Birmingham researchers identify how Salmonella infections can lead to life-threatening thrombosis

Scientists show how absence of microbiota has remarkable effect against obesity

Helmholtz Centre for Infection Research scientists identify promising antitumor agent

Pathophysiological biomarkers predict PAH prognosis

Entirely new enzymatic process of DNA synthesis

New research uncovers antibiotic prescription trends across England

Some gut microbes may hold the key to regulating good health, say Oregon scientists

Intravenous PEG-asparaginase use recommended in paediatric ALL

Advancing Intracellular Delivery with LumiPore®

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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