Clinical Trial News and Research

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Study provides new insight into neurofibromin-deficient ER+ breast cancer

An international team of researchers led by scientists at Baylor College of Medicine has new insights into the function of neurofibromin, a tumor suppressor produced by the NF1 gene.

5 Mar 2020

Researchers uncover novel neurotransmitter system in the brain

Neurotransmitters are chemicals that transmit signals between neurons or from neurons to other cells. They interact with specific receptors found in the brain of humans and animals, controlling a variety of biological processes, e.g. fear, anger, pleasure, memory, energy, appetite and sleep.

5 Mar 2020

Study provides new evidence about optimal way to treat BRCA carriers with breast cancer

Commonly known as the breast cancer genes, the BRCA gene family plays a role in repairing damaged DNA. Inherited mutations in the genes BRCA1 or BRCA2 raise the risk of developing breast, ovarian, prostate and other cancers.

5 Mar 2020

AI may help identify newborns at risk for aggressive posterior retinopathy of prematurity

An artificial intelligence device that has been fast-tracked for approval by the Food and Drug Administration may help identify newborns at risk for aggressive posterior retinopathy of prematurity.

4 Mar 2020

Blood pressure control achieved using workplace-based programs

In a new study out of China, a wellness program based at the workplace was seen to improve blood pressure control among the participants. The study titled, “Effect of a Workplace-Based Multi-Component Intervention on Hypertension Control A Randomized Clinical Trial,” in the latest issue of the journal JAMA Cardiology.

4 Mar 2020

Mayo research provides evidence supporting benefit of ablation for heart failure patients with AFib

Only 1 in 13 everyday patients could have participated in a pivotal international clinical trial looking at the use of catheter ablation to treat atrial fibrillation among people with heart failure.

4 Mar 2020

Antidepressant shows promise in helping men with recurrent prostate cancer

An antidepressant in use for decades, repurposed to fight prostate cancer, shows promise in helping patients whose disease has returned following surgery or radiation, a pilot study at USC shows.

4 Mar 2020

Clinical trial shows the effectiveness of electrical stimulation on women with constipation

Electrical stimulation benefited women with constipation in a recent clinical trial published in Alimentary Pharmacology & Therapeutics.

4 Mar 2020

Preclinical data of Ocugen's OCU400 genetic modifier published in Nature Gene Therapy

Ocugen, Inc., a clinical-stage company focused on discovering, developing and commercializing transformative therapies to treat rare and underserved ophthalmic diseases, announced today the publication in Nature Gene Therapy of preclinical data of nuclear hormone receptor gene NR2E3 as a genetic modifier and therapeutic agent to treat multiple retinal degenerative diseases.

3 Mar 2020

Evaluating the safety and effectiveness of investigational drug to manage pediatric myopia

SUNY College of Optometry will take part in a multi-center US clinical trial sponsored by Eyenovia, Inc. to evaluate the safety and effectiveness of an investigational drug, MicroPine, to help slow myopic progression in children 3 to 12 years old.

3 Mar 2020

Inhibiting specific protein could make radiation therapy for colon cancer more effective

Researchers at Washington University School of Medicine in St. Louis appear to have discovered a way to make radiation therapy for colorectal cancer more effective by inhibiting a protein found in cancer cells in the gut.

3 Mar 2020

Density of immune cells could accurately predict survival in patients with stage III colon cancer

The density of immune cells, called tumor infiltrating lymphocytes, when combined with analysis of tumor budding may serve as a method to more accurately predict survival in patients with stage III colon cancer.

3 Mar 2020

Targeted therapy may increase overall survival in patients with pancreatic cancer

Results from 46 patients given treatments that target specific molecular changes in tumor cells suggest that these therapies could help patients with pancreatic cancer whose tumors harbor those changes survive an extra year.

2 Mar 2020

Latest research on physics of the brain to be presented at 2020 APS March Meeting

Understanding the brain has been one of science's greatest challenges. Each discovery only seems to raise countless other questions about the inner workings of this incredibly complex organ.

28 Feb 2020

Study: Antioxidant supplements do not improve semen quality among men with infertility

Antioxidant supplements do not improve semen quality among men with infertility, according to a new study supported by the Eunice Kennedy Shriver National Institute of Child Health and Human Development, part of the National Institutes of Health.

28 Feb 2020

Readers and tweeters dive into debate over ‘Medicare for All’

Your criticism about former Vice President Joe Biden’s "Medicare for All" cost estimates is spot-on but leaves out important savings.

28 Feb 2020

New templates for improving assessment of senior cancer patients

While older adults, defined as those 65 and older, make up the largest percentage of cancer patients and survivors, this group is not adequately represented in clinical trials, research at the University of Cincinnati has shown.

28 Feb 2020

Researchers show how investigational antiviral drug stops coronavirus

A team of academic and industry researchers is reporting new findings about how exactly an investigational antiviral drug stops coronaviruses.

28 Feb 2020

Boosting immune cells to treat eczema

A new drug regimen is reported to have marked benefits in treating the troublesome and distressing skin condition called eczema. The study, published in February 2020 in the journal Science Translational Medicine, shows that boosting the levels of a type of immune cell called natural killer cells can be a more effective way to treat eczema in a mouse study.

27 Feb 2020

New clinical trial uses universal natural killer cell approach to treat acute myeloid leukemia

A new, phase I clinical trial offered The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute will treat patients with relapsed or refractory acute myeloid leukemia using a novel universal natural killer cell approach.

27 Feb 2020

Clinical Trial News and Research

Study provides new insight into neurofibromin-deficient ER+ breast cancer

Researchers uncover novel neurotransmitter system in the brain

Study provides new evidence about optimal way to treat BRCA carriers with breast cancer

AI may help identify newborns at risk for aggressive posterior retinopathy of prematurity

Blood pressure control achieved using workplace-based programs

Mayo research provides evidence supporting benefit of ablation for heart failure patients with AFib

Antidepressant shows promise in helping men with recurrent prostate cancer

Clinical trial shows the effectiveness of electrical stimulation on women with constipation

Preclinical data of Ocugen's OCU400 genetic modifier published in Nature Gene Therapy

Evaluating the safety and effectiveness of investigational drug to manage pediatric myopia

Inhibiting specific protein could make radiation therapy for colon cancer more effective

Density of immune cells could accurately predict survival in patients with stage III colon cancer

Targeted therapy may increase overall survival in patients with pancreatic cancer

Latest research on physics of the brain to be presented at 2020 APS March Meeting

Study: Antioxidant supplements do not improve semen quality among men with infertility

Readers and tweeters dive into debate over ‘Medicare for All’

New templates for improving assessment of senior cancer patients

Researchers show how investigational antiviral drug stops coronavirus

Boosting immune cells to treat eczema

New clinical trial uses universal natural killer cell approach to treat acute myeloid leukemia

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