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Urgent action needed to address disparities in women’s heart health

Investing in and improving research, awareness and equity in women's heart health are critical for the health and well-being of women, according to a new Presidential Advisory from the American Heart Association, published today in the Association's flagship journal Circulation.

9 May 2022

LJI researchers uncover new drug target for severe asthma, lung fibrosis

If you've ever struggled to breathe, you've had a moment of hypoxia - a lack of oxygen. Hypoxia can have long-term effects. In fact, doctors describe hypoxia as an "initial insult."

9 May 2022

Study identifies interleukin-6 as a potential target in refining cancer therapies

Immune checkpoint inhibitors have revolutionized the treatment of many cancers by using our body's immune system to kill cancer.

9 May 2022

Correlating symptoms with COVID-19 test positivity in children

Researchers analyzed the relationship between suspected symptoms of COVID-19 and test positivity in children.

9 May 2022

Diagnostic performance of monocyte distribution width and other leukocyte parameters for SARS-CoV-2 and influenza infection

Researchers used a novel diagnostic screen, monocyte distribution width for SARS-CoV-2 and influenza infection.

9 May 2022

Evidence of croup associated with SARS-CoV-2

A new study published in the Journal of Pediatric Infectious Diseases Society aimed to characterize the clinical features of SARS-CoV-2-associated croup among children presenting to the ED during the phase when Omicron variant transmission was high.

9 May 2022

Neuroscientists discover a new facet to caloric restriction that dramatically extends life span

A new study in mice led by neuroscientists at UT Southwestern's Peter O'Donnell Jr. Brain Institute shows that it's not just calories that count.

6 May 2022

Single-cell RNA sequencing reveals characteristics of myeloid immune cells in coronary plaque

Through single-cell RNA sequencing, a research group has successfully illuminated the characteristics of Myeloid immune cells in coronary plaque, which causes acute coronary syndrome (this term includes conditions such as unstable angina and acute myocardial infarction (heart attack)).

6 May 2022

Study reveals why some lungs are protected against COVID

COVID-19 vaccines have saved at least a million lives in the United States alone, but for many people, a lingering fear remains: if - or when - they get hit by the coronavirus, just how bad will it be? Will they breeze through with little more than a sore throat - or will it saddle them with long-term complications, perhaps even push them to the brink of death?

6 May 2022

Scientists explore immunopathology of COVID-19

Researchers explored the interactions between severe acute respiratory syndrome coronavirus 2 and the host in the development of COVID-19.

6 May 2022

miRNAs associated with varying clinical presentations of SARS-CoV-2

A recent article published in the journal iSCIENCE demonstrated different micro ribonucleic acids (miRNAs) linked with various presentations of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections.

5 May 2022

Reduced-calorie diet plus time-restricted eating promote longevity in mice

One recipe for longevity is simple, if not easy to follow: eat less. Studies in a variety of animals have shown that restricting calories can lead to a longer, healthier life.

5 May 2022

Acute hepatitis and adenovirus infection among pediatric patients in Alabama

A new study published by the Centers for Disease Control and Prevention (CDC) today, "Acute Hepatitis and Adenovirus Infection Among Children - Alabama, October 2021–February 2022" provides additional clinical and epidemiologic information from an ongoing investigation involving children in Alabama with hepatitis (inflammation of the liver) of unknown cause.

5 May 2022

Effects of diet on COVID-19 outcomes

A new study explores the effects of diet on COVID-19 outcomes.

5 May 2022

Discovery provides critical clues to why many immunotherapies trigger dangerous side effects

It's not often that a failed clinical trial leads to a scientific breakthrough. When patients in the UK started showing adverse side effects during a cancer immunotherapy trial, researchers at La Jolla Institute for Immunology (LJI) Center for Cancer Immunotherapy and University of Liverpool went back through the data and worked with patient samples to see what went wrong.

5 May 2022

Inflammation News and Research

Urgent action needed to address disparities in women’s heart health

LJI researchers uncover new drug target for severe asthma, lung fibrosis

Study identifies interleukin-6 as a potential target in refining cancer therapies

Correlating symptoms with COVID-19 test positivity in children

Diagnostic performance of monocyte distribution width and other leukocyte parameters for SARS-CoV-2 and influenza infection

Evidence of croup associated with SARS-CoV-2

Neuroscientists discover a new facet to caloric restriction that dramatically extends life span

Single-cell RNA sequencing reveals characteristics of myeloid immune cells in coronary plaque

Study reveals why some lungs are protected against COVID

Scientists explore immunopathology of COVID-19

miRNAs associated with varying clinical presentations of SARS-CoV-2

Reduced-calorie diet plus time-restricted eating promote longevity in mice

Acute hepatitis and adenovirus infection among pediatric patients in Alabama

Effects of diet on COVID-19 outcomes

Discovery provides critical clues to why many immunotherapies trigger dangerous side effects

Fecal microbiota transplant can reverse hallmarks of aging in mice

Scientists investigate the association between walking pace and leucocyte telomere length

Study assesses the efficacy and safety of lithium treatment in patients infected with severe SARS-CoV-2

Blood vessels use endothelial communication system to control cardiovascular activity, study shows

High-performing age-stratified machine-learning models for the prediction of the severity of COVID-19 progression

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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