Antigen News and Research

RSS

Stressgen granted U.S. patent providing coverage for the manufacture of HspE7

Stressgen Biotechnologies announced today that the U.S. Patent and Trademark Office granted US Patent Number 6,900,035, covering methods of manufacturing HspE7, the Company's lead product candidate for human papillomavirus (HPV)- related diseases and cancer.

13 Jul 2005

Blood testing links common foods and irritable bowel syndrome

Researchers using comparison trials determined that irritable bowel syndrome (IBS) patients have elevated food-specific IgG4 antibodies to common foods such as wheat, beef, pork, lamb, and soya bean. These findings are published in the July issue of The American Journal of Gastroenterology.

13 Jul 2005

PSA screening of asymptomatic men reduced risk of metastatic prostate cancer by 35 per cent

Early screening of prostate cancer in asymptomatic men may reduce their risk of death from metastatic prostate cancer by as much as 35 per cent, researchers from the University of Toronto have found.

11 Jul 2005

Accuracy of PSA screening for detecting prostate cancer

A new study indicates there is no specific PSA value that has both high sensitivity and high specificity for monitoring healthy men for prostate cancer, but rather there is a continuum of prostate cancer risk at all values of PSA, according to a study in the July 6 issue of JAMA: The Journal of the American Medical Association.

6 Jul 2005

Scientists solve structure of a critical innate immune system protein

Scientists at The Scripps Research Institute have solved the structure of a crucial human immune system molecule called TLR3, an acronym for Toll-like receptor three. In an upcoming issue of the journal Science, the protein is described as a large horseshoe-shaped coil composed of 23 leucine-rich repeats (LRRs).

27 Jun 2005

Immunomedics awarded U.S. and Australian patents

Immunomedics announced that it has received notices that the U.S. and Australian patent offices have allowed claims in respective patent applications covering methods for treating a wide range of autoimmune diseases using monoclonal antibodies that bind to the CD22 antigen present on B-lymphocytes.

16 Jun 2005

Vical receives $12 Million HIV vaccine order

Vical Incorporated announced today the receipt of approximately $12.1 million in production orders for multiple clinical lots of DNA vaccines against HIV for the Vaccine Research Center (VRC) at the National Institute of Allergy and Infectious Diseases, under a subcontract managed by SAIC-Frederick, Inc.

16 Jun 2005

Jumping genes help detemine uniqueness of individual brains

Scientists at the Salk Institute for Biological Studies may have found one explanation for the puzzling variety in brain organization and function: mobile elements, pieces of DNA that can jump from one place in the genome to another, randomly changing the genetic information in single brain cells.

15 Jun 2005

SARS vaccine produced from plants

According to new research, a vaccine has been produced in genetically engineered tomato and tobacco plants, which triggers anti-SARS antibodies in mice.

15 Jun 2005

Chemotherapy for brain tumors is boosted after vaccine targets resistance-related TRP-2 antigen

In the August issue of the journal Oncogene, researchers at Cedars-Sinai Medical Center's Maxine Dunitz Neurosurgical Institute describe a molecular mechanism that appears to make malignant brain tumors more vulnerable to chemotherapy after they have been treated with the dendritic cell vaccine.

13 Jun 2005

Diversity of HLA genotypes in humans is shaped to a significant degree by pathogens

The great physical diversity that evolution has forged in human beings is in evidence wherever we look, but the genes exhibiting the greatest diversity at the DNA level happen to function in a wholly invisible process: immunity. Genes encoding the Human Leukocyte Antigen (HLA) proteins are among the most diverse in the human genome, and scientists have proposed a number of hypotheses to explain why.

6 Jun 2005

Research shows how a virus uses the gene silencing machinery for its own infectious purposes

In the latest version of the hide-and-seek game between pathogens and the hosts they infect, researchers have found that a virus appears to cloak itself with a recently discovered gene silencing device to evade detection and destruction by immune cells.

3 Jun 2005

New vaccine against whooping cough is effective in teens and adults

The Journal of the American Medical Association (JAMA) has announced that a study to be published in the June 22/29 issue found that a new vaccine against whooping cough is effective in teens and adults, carriers of the contagious respiratory disease so dangerous to infants.

3 Jun 2005

Booster vaccine that includes protection against pertussis shows promise

A new combination vaccine not yet on the market appears to provide a booster for immunity against tetanus, diphtheria, and pertussis for adolescents and adults and was found to have a similar overall safety profile when compared to the current licensed tetanus-diphtheria vaccine, according to a new study in JAMA.

3 Jun 2005

Leprosy microbes lead scientists to immune discovery

With the unusual opportunity that human leprosy infections provide for study of human immune responses, scientists have discovered how the body's early warning system prompts a rapid immune response by two separate armies of defensive cells.

29 May 2005

Is winter flu worse because of exercise-induced 'window of susceptibility'?

When you exercise or work outside in winter, that dry feeling at the back of your throat indicates the cold air has irritated your throat. Racehorses share a similar experience: exercising in below-freezing air causes mild airway injury.

26 May 2005

What is Sick Building Syndrome?

Science-based identification of mold and other causes of Sick Building Syndrome may improve its management, say plant pathologists with The American Phytopathological Society (APS).

26 May 2005

Obesity appears to increase the risk of prostate cancer

The obesity study examined the association between body mass index - weight to height ratio - and prostate cancer in 787 men undergoing biopsy due to an elevated tumor marker in the blood or an abnormal physical exam at a Veterans Affairs hospital in California between 1998 and 2002.

23 May 2005

Infants with Krabbe disease saved by cord blood stem cells

Children with a fatal genetic disorder called Krabbe Disease can be saved and their brain development preserved if they receive stem cells from umbilical cord blood before symptoms of the disease develop, according to a study published in the current issue of the New England Journal of Medicine.

20 May 2005

New combination vaccine effective against plague

Plague, a bacterium that ravaged Europe in the Middle Ages and is today one of the most feared potential agents of bio-terrorism, may have met its match, according to Wake Forest University School of Medicine scientists.

18 May 2005